Manuela Cominelli相关文献与解析，生知库

Enrique Blanco-Carmona ，Ashwin Narayanan ，Inmaculada Hernandez ，Juan C Nieto ，Marc Elosua-Bayes ，Xueyuan Sun ，Claudia Schmidt ，Necmettin Pamir ，Koray Özduman ，Christel Herold-Mende ，Francesca Pagani ，Manuela Cominelli ，Julian Taranda ，Wolfgang Wick ，Andreas von Deimling ，Pietro Luigi Poliani ，Michael Rehli ，Matthias Schlesner ，Holger Heyn ，Şevin Turcan

胶质细胞

细胞生物学

肿瘤

Coexisting cancer stem cells with heterogeneous gene amplifications, transcriptional profiles, and malignancy are isolated from single glioblastomas

从单个胶质母细胞瘤中分离出具有异质基因扩增、转录谱和恶性肿瘤的共存癌症干细胞

期刊:Cell Reports

影响因子:7.5

doi:10.1016/j.celrep.2023.112816

Francesca De Bacco, Francesca Orzan, Giovanni Crisafulli, Marta Prelli, Claudio Isella, Elena Casanova, Raffaella Albano, Gigliola Reato, Jessica Erriquez, Antonio D'Ambrosio, Mara Panero, Carmine Dall'Aglio, Laura Casorzo, Manuela Cominelli, Francesca Pagani, Antonio Melcarne, Pietro Zeppa, Roberto

Human iPSC-Derived 3D Hepatic Organoids in a Miniaturized Dynamic Culture System

微型动态培养系统中的人类 iPSC 衍生 3D 肝类器官

期刊:Biomedicines

影响因子:3.9

doi:10.3390/biomedicines11082114

Serena Calamaio, Marialaura Serzanti, Jennifer Boniotti, Annamaria Fra, Emirena Garrafa, Manuela Cominelli, Rosanna Verardi, Pietro Luigi Poliani, Silvia Dotti, Riccardo Villa, Giovanna Mazzoleni, Patrizia Dell'Era, Nathalie Steimberg

Targeting mTOR Pathway in PTEN Deleted Newly Isolated Chordoma Cell Line

靶向 PTEN 缺失的新分离脊索瘤细胞系中的 mTOR 通路

期刊:Journal of Personalized Medicine

影响因子:3

doi:10.3390/jpm13030425

Francesca Pagani, Magdalena Gryzik, Elena Somenza, Manuela Cominelli, Piera Balzarini, Alberto Schreiber, Davide Mattavelli, Piero Nicolai, Francesco Doglietto, Pietro Luigi Poliani

β-Galactosylceramidase Deficiency Causes Upregulation of Long Pentraxin-3 in the Central Nervous System of Krabbe Patients and Twitcher Mice

β-半乳糖苷神经酰胺酶缺乏导致克拉伯病患者和 Twitcher 小鼠中枢神经系统中长五聚蛋白-3 上调

期刊:International Journal of Molecular Sciences

影响因子:0.7

doi:10.3390/ijms23169436

Daniela Coltrini, Adwaid Manu Krishna Chandran, Mirella Belleri, Pietro L Poliani, Manuela Cominelli, Francesca Pagani, Miriam Capra, Stefano Calza, Simona Prioni, Laura Mauri, Alessandro Prinetti, Julia K Kofler, Maria L Escolar, Marco Presta

神经

发表日期：2022

文献求助收藏

mTORC1 promotes malignant large cell/anaplastic histology and is a targetable vulnerability in SHH-TP53 mutant medulloblastoma

mTORC1 促进恶性大细胞/间变性组织学，是 SHH-TP53 突变型髓母细胞瘤的一个可靶向弱点

期刊:JCI Insight

影响因子:6.3

doi:10.1172/jci.insight.153462

Valentina Conti, Manuela Cominelli, Valentina Pieri, Alberto L Gallotti, Ilaria Pagano, Matteo Zanella, Stefania Mazzoleni, Flavia Pivetta, Monica Patanè, Giulia M Scotti, Ignazio S Piras, Bianca Pollo, Andrea Falini, Alessio Zippo, Antonella Castellano, Roberta Maestro, Pietro L Poliani, Rossella G

EBF1 is expressed in pericytes and contributes to pericyte cell commitment

EBF1 在周细胞中表达，并有助于周细胞的分化

期刊:Histochemistry and Cell Biology

影响因子:2.1

doi:10.1007/s00418-021-02015-7

Francesca Pagani, Elisa Tratta, Patrizia Dell'Era, Manuela Cominelli, Pietro Luigi Poliani

Human and mouse single-nucleus transcriptomics reveal TREM2-dependent and TREM2-independent cellular responses in Alzheimer's disease

人类和小鼠单核转录组学揭示阿尔茨海默病中的 TREM2 依赖性和 TREM2 非依赖性细胞反应

期刊:Nature Medicine

影响因子:58.7

doi:10.1038/s41591-019-0695-9

Yingyue Zhou, Wilbur M Song, Prabhakar S Andhey, Amanda Swain, Tyler Levy, Kelly R Miller, Pietro L Poliani, Manuela Cominelli, Shikha Grover, Susan Gilfillan, Marina Cella, Tyler K Ulland, Konstantin Zaitsev, Akinori Miyashita, Takeshi Ikeuchi, Makoto Sainouchi, Akiyoshi Kakita, David A Bennett, Ju

The proneural gene ASCL1 governs the transcriptional subgroup affiliation in glioblastoma stem cells by directly repressing the mesenchymal gene NDRG1

前神经基因 ASCL1 通过直接抑制间充质基因 NDRG1 来控制胶质母细胞瘤干细胞中的转录亚组归属

期刊:Cell Death and Differentiation

影响因子:13.7

doi:10.1038/s41418-018-0248-7

Ashwin Narayanan, Filippo Gagliardi, Alberto L Gallotti, Stefania Mazzoleni, Manuela Cominelli, Luca Fagnocchi, Mauro Pala, Ignazio S Piras, Paola Zordan, Nicole Moretta, Elisa Tratta, Gianluca Brugnara, Luisa Altabella, Giuseppina Bozzuto, Petra Gorombei, Agnese Molinari, Rose-Ann Padua, Alessandro

Tuberous sclerosis complex-associated CNS abnormalities depend on hyperactivation of mTORC1 and Akt

结节性硬化症相关中枢神经系统异常依赖于 mTORC1 和 Akt 的过度激活

期刊:Journal of Clinical Investigation

影响因子:13.3

doi:10.1172/JCI96342

Paola Zordan, Manuela Cominelli, Federica Cascino, Elisa Tratta, Pietro L Poliani, Rossella Galli

Tumor heterogeneity and tumor-microglia interactions in primary and recurrent IDH1-mutant gliomas

原发性和复发性IDH1突变型胶质瘤的肿瘤异质性和肿瘤-小胶质细胞相互作用

Coexisting cancer stem cells with heterogeneous gene amplifications, transcriptional profiles, and malignancy are isolated from single glioblastomas

从单个胶质母细胞瘤中分离出具有异质基因扩增、转录谱和恶性肿瘤的共存癌症干细胞

Human iPSC-Derived 3D Hepatic Organoids in a Miniaturized Dynamic Culture System

微型动态培养系统中的人类 iPSC 衍生 3D 肝类器官

Targeting mTOR Pathway in PTEN Deleted Newly Isolated Chordoma Cell Line

靶向 PTEN 缺失的新分离脊索瘤细胞系中的 mTOR 通路

β-Galactosylceramidase Deficiency Causes Upregulation of Long Pentraxin-3 in the Central Nervous System of Krabbe Patients and Twitcher Mice

β-半乳糖苷神经酰胺酶缺乏导致克拉伯病患者和 Twitcher 小鼠中枢神经系统中长五聚蛋白-3 上调

mTORC1 promotes malignant large cell/anaplastic histology and is a targetable vulnerability in SHH-TP53 mutant medulloblastoma

mTORC1 促进恶性大细胞/间变性组织学，是 SHH-TP53 突变型髓母细胞瘤的一个可靶向弱点

EBF1 is expressed in pericytes and contributes to pericyte cell commitment

EBF1 在周细胞中表达，并有助于周细胞的分化

Human and mouse single-nucleus transcriptomics reveal TREM2-dependent and TREM2-independent cellular responses in Alzheimer's disease

人类和小鼠单核转录组学揭示阿尔茨海默病中的 TREM2 依赖性和 TREM2 非依赖性细胞反应

The proneural gene ASCL1 governs the transcriptional subgroup affiliation in glioblastoma stem cells by directly repressing the mesenchymal gene NDRG1

前神经基因 ASCL1 通过直接抑制间充质基因 NDRG1 来控制胶质母细胞瘤干细胞中的转录亚组归属

Tuberous sclerosis complex-associated CNS abnormalities depend on hyperactivation of mTORC1 and Akt

结节性硬化症相关中枢神经系统异常依赖于 mTORC1 和 Akt 的过度激活