Manuela Nieto-Rostro相关文献与解析，生知库

LRP1 influences trafficking of N-type calcium channels via interaction with the auxiliary α2δ-1 subunit

LRP1 通过与辅助 α2δ-1 亚基相互作用影响 N 型钙通道的运输

期刊:Scientific Reports

影响因子:3.8

doi:10.1038/srep43802

Ivan Kadurin, Simon W Rothwell, Beatrice Lana, Manuela Nieto-Rostro, Annette C Dolphin

信号转导

发表日期：2017

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A CaV2.1 N-terminal fragment relieves the dominant-negative inhibition by an Episodic ataxia 2 mutant

CaV2.1 N 端片段可缓解发作性共济失调 2 突变体的显性负抑制

期刊:Neurobiology of Disease

影响因子:5.1

doi:10.1016/j.nbd.2016.05.020

Shehrazade Dahimene, Karen M Page, Manuela Nieto-Rostro, Wendy S Pratt, Marianna D'Arco, Annette C Dolphin

信号转导

发表日期：2016

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Thrombospondin-4 reduces binding affinity of [(3)H]-gabapentin to calcium-channel α2δ-1-subunit but does not interact with α2δ-1 on the cell-surface when co-expressed

血小板反应蛋白-4 降低了 [(3)H]-加巴喷丁与钙通道 α2δ-1 亚基的结合亲和力，但在共表达时不会与细胞表面的 α2δ-1 相互作用

期刊:Scientific Reports

影响因子:3.8

doi:10.1038/srep24531

Beatrice Lana, Karen M Page, Ivan Kadurin, Shuxian Ho, Manuela Nieto-Rostro, Annette C Dolphin

Effect of knockout of α2δ-1 on action potentials in mouse sensory neurons

α2δ-1 敲除对小鼠感觉神经元动作电位的影响

期刊:Philosophical Transactions of the Royal Society of London Series B-Containing Papers of a Biological Character

影响因子:

doi:10.1098/rstb.2015.0430

Wojciech Margas, Laurent Ferron, Manuela Nieto-Rostro, Arnold Schwartz, Annette C Dolphin

Fragile X mental retardation protein controls synaptic vesicle exocytosis by modulating N-type calcium channel density

脆性X智力低下蛋白通过调节N型钙通道密度来控制突触囊泡外排

期刊:Nature Communications

影响因子:14.7

doi:10.1038/ncomms4628

Laurent Ferron, Manuela Nieto-Rostro, John S Cassidy, Annette C Dolphin

囊泡

发表日期：2014

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The increased trafficking of the calcium channel subunit alpha2delta-1 to presynaptic terminals in neuropathic pain is inhibited by the alpha2delta ligand pregabalin

在神经性疼痛中，钙通道亚基 alpha2delta-1 向突触前末梢的运输增加，受到 alpha2delta 配体普瑞巴林的抑制

期刊:Journal of Neuroscience

影响因子:4.4

doi:10.1523/JNEUROSCI.0356-09.2009

Claudia S Bauer, Manuela Nieto-Rostro, Wahida Rahman, Alexandra Tran-Van-Minh, Laurent Ferron, Leon Douglas, Ivan Kadurin, Yorain Sri Ranjan, Laura Fernandez-Alacid, Neil S Millar, Anthony H Dickenson, Rafael Lujan, Annette C Dolphin

神经

发表日期：2009

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The ducky(2J) mutation in Cacna2d2 results in reduced spontaneous Purkinje cell activity and altered gene expression

Cacna2d2 中的 ducky(2J) 突变导致自发性浦肯野细胞活动减少和基因表达改变

期刊:Journal of Neuroscience

影响因子:4.4

doi:10.1523/JNEUROSCI.3080-06.2006

Roberta Donato, Karen M Page, Dietlind Koch, Manuela Nieto-Rostro, Isabelle Foucault, Anthony Davies, Tonia Wilkinson, Michele Rees, Frances A Edwards, Annette C Dolphin

Interaction via a key tryptophan in the I-II linker of N-type calcium channels is required for beta1 but not for palmitoylated beta2, implicating an additional binding site in the regulation of channel voltage-dependent properties

β1 需要通过 N 型钙通道 I-II 连接体中的关键色氨酸进行相互作用，而棕榈酰化 β2 则不需要，这表明在通道电压依赖性特性的调节中存在额外的结合位点

期刊:Journal of Neuroscience

影响因子:4.4

doi:10.1523/JNEUROSCI.1137-05.2005

Jérôme Leroy, Mark W Richards, Adrian J Butcher, Manuela Nieto-Rostro, Wendy S Pratt, Anthony Davies, Annette C Dolphin

发表日期：2005

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Nerve injury increases native Ca V 2.2 trafficking in dorsal root ganglion mechanoreceptors

神经损伤增加背根神经节机械感受器中天然 Ca V 2.2 的运输

LRP1 influences trafficking of N-type calcium channels via interaction with the auxiliary α2δ-1 subunit

LRP1 通过与辅助 α2δ-1 亚基相互作用影响 N 型钙通道的运输

A CaV2.1 N-terminal fragment relieves the dominant-negative inhibition by an Episodic ataxia 2 mutant

CaV2.1 N 端片段可缓解发作性共济失调 2 突变体的显性负抑制

Thrombospondin-4 reduces binding affinity of [(3)H]-gabapentin to calcium-channel α2δ-1-subunit but does not interact with α2δ-1 on the cell-surface when co-expressed

血小板反应蛋白-4 降低了 [(3)H]-加巴喷丁与钙通道 α2δ-1 亚基的结合亲和力，但在共表达时不会与细胞表面的 α2δ-1 相互作用

Effect of knockout of α2δ-1 on action potentials in mouse sensory neurons

α2δ-1 敲除对小鼠感觉神经元动作电位的影响

Fragile X mental retardation protein controls synaptic vesicle exocytosis by modulating N-type calcium channel density

脆性X智力低下蛋白通过调节N型钙通道密度来控制突触囊泡外排

The increased trafficking of the calcium channel subunit alpha2delta-1 to presynaptic terminals in neuropathic pain is inhibited by the alpha2delta ligand pregabalin

在神经性疼痛中，钙通道亚基 alpha2delta-1 向突触前末梢的运输增加，受到 alpha2delta 配体普瑞巴林的抑制

The ducky(2J) mutation in Cacna2d2 results in reduced spontaneous Purkinje cell activity and altered gene expression

Cacna2d2 中的 ducky(2J) 突变导致自发性浦肯野细胞活动减少和基因表达改变

Interaction via a key tryptophan in the I-II linker of N-type calcium channels is required for beta1 but not for palmitoylated beta2, implicating an additional binding site in the regulation of channel voltage-dependent properties

β1 需要通过 N 型钙通道 I-II 连接体中的关键色氨酸进行相互作用，而棕榈酰化 β2 则不需要，这表明在通道电压依赖性特性的调节中存在额外的结合位点