日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

A phase III, randomised, double-blind, multi-dose, placebo- and naproxen-controlled study to evaluate the efficacy and safety of fasinumab in patients with pain due to osteoarthritis of the knee or hip

一项III期、随机、双盲、多剂量、安慰剂和萘普生对照研究，旨在评估法西单抗治疗膝关节或髋关节骨关节炎疼痛患者的疗效和安全性。

期刊:RMD Open
影响因子:4.7
doi:10.1136/rmdopen-2025-006436
DiMartino, Stephen J; Cicirello, Helen; Magyar, Andrew; Eng, Simon; Ho, Tina; Manvelian, Garen; Patel, Yamini; Pervin, Kauser; Trinh, Ngan; Fetell, Michael; Braunstein, Ned; Geba, Gregory P; Dakin, Paula
关节炎
发表日期：2026
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Identification of alkaline phosphatase as a putative biomarker of anti-NGF treatment-associated arthropathies: Machine learning-assisted analyses of clinical trial data

碱性磷酸酶作为抗NGF治疗相关关节病潜在生物标志物的鉴定：基于机器学习的临床试验数据分析

期刊:Osteoarthritis and Cartilage Open
影响因子:2.8
doi:10.1016/j.ocarto.2025.100735
Wipperman, Matthew F; Ehmann, Peter J; McIntyre, Debra A G; Wang, Chen Guang; Gao, Haitao; Banerjee, Poulabi; Ogawa, Kei; Ushirogawa, Yoshiteru; Chio, Erica; Li, Dateng; Hectors, Stefanie; Wei, Henry G; Hamilton, Jennifer D; Hamon, Sara C; Ota, Kristie T; Eng, Simon; Manvelian, Garen; Ho, Tina; Musser, Bret J; DiMartino, Stephen J; Patel, Yamini; Geba, Gregory P
NGF
发表日期：2026
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Evidence for cPLA2 activation in Alzheimer's disease synaptic pathology

阿尔茨海默病突触病理中cPLA2激活的证据

期刊:Acta Neuropathologica Communications
影响因子:
doi:10.1186/s40478-025-02214-6
Ma, Qiu-Lan; Ebright, Brandon; Li, Boyang; Li, Jing; Galvan, Jasmin; Sanchez, Ashley; Renteln, Michael; Dikeman, Dante; Wang, Shaowei; Kerman, Bilal E; Wang, Xinhui; Manvelian, Marina; Yu, Xiaohui; Seidler, Paul; Gutierrez-Grebenkova, Berenice; Hjelm, Brooke E; Hawes, Debra; Hiniker, Anne E; Hurth, Kyle M; Bennett, David A; Louie, Stan G; Chui, Helena C; Limon, Agenor; Arvanitakis, Zoe; Yassine, Hussein N
cPLA2
阿尔茨海默症
神经科学
发表日期：2026
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Effect of PCSK9 Inhibition With Alirocumab in Patients With Probable Familial Hypercholesterolemia or Type III Hyperlipoproteinemia: Results From the ODYSSEY OUTCOMES Trial

使用阿利西尤单抗抑制PCSK9对可能患有家族性高胆固醇血症或III型高脂蛋白血症患者的影响：ODYSSEY OUTCOMES试验的结果

期刊:Journal of the American Heart Association
影响因子:5.3
doi:10.1161/JAHA.124.041190
Geba, Gregory P; Mohammadi, Kusha A; Damask, Amy; Paulding, Charles; Lotta, Luca A; Hindy, George; Pordy, Robert; Manvelian, Garen; Shapiro, Michael D; Bittner, Vera A; Bhatt, Deepak L; Szarek, Michael; Schwartz, Gregory G; Steg, Ph Gabriel; Fazio, Sergio
CSK
PCSK9
代谢
发表日期：2025
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Efficacy and safety of fasinumab in an NSAID-controlled study in patients with pain due to osteoarthritis of the knee or hip

在非甾体抗炎药对照研究中，法西单抗治疗膝关节或髋关节骨关节炎疼痛患者的疗效和安全性

期刊:BMC Musculoskeletal Disorders
影响因子:2.4
doi:10.1186/s12891-025-08402-8
DiMartino, Stephen J; Gao, Haitao; Eng, Simon; Valenzuela, Guillermo; Fuerst, Thomas; Emeremni, Chetachi; Ho, Tina; Hassan, Hazem E; Turner, Kenneth C; Davis, John D; Zaim, Souhil; Chao, Jesse; Patel, Yamini; Brener, Lillian; Trinh, Ngan; Manvelian, Garen; Fetell, Michael; Braunstein, Ned; Geba, Gregory P; Dakin, Paula
关节炎
发表日期：2025
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The Effects of Fasinumab on Peripheral Nerve Function and Ganglion Anatomy: Results From a Randomized, Double-Blind, Placebo-Controlled Study in Patients With Pain Due to Osteoarthritis of the Knee or Hip, and a Series of Nonclinical Studies

法西单抗对周围神经功能和神经节解剖结构的影响：一项针对膝关节或髋关节骨关节炎疼痛患者的随机、双盲、安慰剂对照研究及一系列非临床研究的结果

期刊:Current Therapeutic Research-Clinical and Experimental
影响因子:1.5
doi:10.1016/j.curtheres.2025.100813
Eng, Simon; Fetell, Michael; Gao, Haitao; Mei, Jingning; Trejos, Jesus; Cortes-Burgos, Luz; Ho, Tina; Manvelian, Garen; Patel, Yamini; Trinh, Ngan; Turner, Kenneth C; Hassan, Hazem E; DiMartino, Stephen; Krueger, Pamela; Geba, Gregory P; Braunstein, Ned; Macdonald, Lynn E; Soltys, Randy; Croll, Susan D; Dakin, Paula
关节炎
发表日期：2025
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Alirocumab in Pediatric Patients With Heterozygous Familial Hypercholesterolemia: A Randomized Clinical Trial

阿利西尤单抗治疗杂合子家族性高胆固醇血症患儿：一项随机临床试验

期刊:Jama Pediatrics
影响因子:18
doi:10.1001/jamapediatrics.2023.6477
Santos, Raul D; Wiegman, Albert; Caprio, Sonia; Cariou, Bertrand; Averna, Maurizio; Poulouin, Yann; Scemama, Michel; Manvelian, Garen; Garon, Genevieve; Daniels, Stephen
代谢
发表日期：2024
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Safety of the PCSK9 inhibitor alirocumab: insights from 47 296 patient-years of observation

PCSK9抑制剂阿利西尤单抗的安全性：来自47296患者年观察的启示

期刊:European Heart Journal-Cardiovascular Pharmacotherapy
影响因子:6.1
doi:10.1093/ehjcvp/pvae025
Goodman, Shaun G; Steg, Philippe Gabriel; Szarek, Michael; Bhatt, Deepak L; Bittner, Vera A; Diaz, Rafael; Harrington, Robert A; Jukema, J Wouter; White, Harvey D; Zeiher, Andreas M; Manvelian, Garen; Pordy, Robert; Poulouin, Yann; Stipek, Wanda; Garon, Genevieve; Schwartz, Gregory G
CSK
PCSK9
发表日期：2024
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Alirocumab and chest pain after acute coronary syndrome: An analysis of ODYSSEY OUTCOMES

阿利西尤单抗治疗急性冠脉综合征后胸痛：ODYSSEY OUTCOMES 研究分析

期刊:American Journal of Preventive Cardiology
影响因子:5.9
doi:10.1016/j.ajpc.2024.100900
Geba, Gregory P; Chen, Ruifeng; Talapatra, Kasturi; Brackin, Taylor; Mohammadi, Kusha A; Pordy, Robert; Manvelian, Garen; Maron, David J; Schwartz, Gregory G; Szarek, Michael; Steg, Ph Gabriel; Fazio, Sergio
发表日期：2024
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Inner engineering is associated with perceived improvements in relationship quality, interpersonal connections, and interpersonal compassion

内在工程与人际关系质量、人际联结和人际同理心的提升密切相关。

期刊:Frontiers in Psychology
影响因子:2.9
doi:10.3389/fpsyg.2024.1454293
Jafari, Nashaw; Manvelian, Atina; Mohamed, Enas; Rayapuraju, Akila; Orui, Hibiki; Alkuhaimi, Sultan; Reed, Preeti Upadhyay; Subramaniam, Balachundhar
发表日期：2024
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