日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

FGD3 mediates lytic cell death, enhancing efficacy and immunogenicity of chemotherapy agents in breast cancer.

FGD3 介导细胞溶解性死亡,增强化疗药物在乳腺癌中的疗效和免疫原性。

Zhu Junyao, Dai Xinyi, Ghosh Santanu, Wei Elaine, Mao Chengjian, Jiang Qianjin, Spaulding Abigail J, Mulligan Michael P, Romero Roger, Han Yoo Jane, Boudreau Matthew W, Olopade Olufunmilayo, Hergenrother Paul J, Shapiro David J

A necrosis inducer promotes an immunogenic response and destroys ovarian cancers in mouse xenografts and patient ascites organoids.

坏死诱导剂可促进免疫反应,并破坏小鼠异种移植和患者腹水类器官中的卵巢癌

Duraki Darjan, Jabeen Musarrat, Mao Chengjian, Wang Lawrence, Ghosh Santanu, Dai Xinyi, Zhu Junyao, Boudreau Matthew W, Nelson Erik R, Hergenrother Paul J, Cheng Georgina, Shapiro David J

A small-molecule activator of the unfolded protein response eradicates human breast tumors in mice

一种小分子未折叠蛋白反应激活剂可根除小鼠体内的人类乳腺肿瘤。

Boudreau, Matthew W; Duraki, Darjan; Wang, Lawrence; Mao, Chengjian; Kim, Ji Eun; Henn, Madeline A; Tang, Bingtao; Fanning, Sean W; Kiefer, Jeffrey; Tarasow, Theodore M; Bruckheimer, Elizabeth M; Moreno, Ramon; Mousses, Spyro; Greene, Geoffrey L; Roy, Edward J; Park, Ben Ho; Fan, Timothy M; Nelson, Erik R; Hergenrother, Paul J; Shapiro, David J

Silencing lncRNA HOTAIR declines synovial inflammation and synoviocyte proliferation and promotes synoviocyte apoptosis in osteoarthritis rats by inhibiting Wnt/β-catenin signaling pathway

沉默 lncRNA HOTAIR 通过抑制 Wnt/β-catenin 信号通路减轻骨关节炎大鼠滑膜炎症和滑膜细胞增殖并促进滑膜细胞凋亡

Tian Mao, Chengjian He, Huafeng Wu, Bo Yang, Xin Li

Protein kinase C-α is upregulated by IMP1 in melanoma and is linked to poor survival.

在黑色素瘤中,蛋白激酶 C-α 受 IMP1 上调,且与生存率低有关

Mahapatra Lily, Andruska Neal, Mao Chengjian, Gruber Stephen B, Johnson Timothy M, Fullen Douglass R, Raskin Leon, Shapiro David J

High-throughput fluorescence anisotropy screen for inhibitors of the oncogenic mRNA binding protein, IMP-1.

利用高通量荧光各向异性筛选致癌 mRNA 结合蛋白 IMP-1 的抑制剂

Mahapatra Lily, Mao Chengjian, Andruska Neal, Zhang Chen, Shapiro David J

Small molecule inhibitors as probes for estrogen and androgen receptor action

小分子抑制剂作为雌激素和雄激素受体作用的探针

Shapiro, David J; Mao, Chengjian; Cherian, Milu T

A noncompetitive small molecule inhibitor of estrogen-regulated gene expression and breast cancer cell growth that enhances proteasome-dependent degradation of estrogen receptor {alpha}

一种非竞争性小分子抑制剂,可抑制雌激素调节基因表达和乳腺癌细胞生长,并增强蛋白酶体依赖性雌激素受体α的降解。

Kretzer, Nicole M; Cherian, Milu T; Mao, Chengjian; Aninye, Irene O; Reynolds, Philip D; Schiff, Rachel; Hergenrother, Paul J; Nordeen, Steven K; Wilson, Elizabeth M; Shapiro, David J

A new small molecule inhibitor of estrogen receptor alpha binding to estrogen response elements blocks estrogen-dependent growth of cancer cells

一种新型小分子抑制剂可抑制雌激素受体α与雌激素反应元件的结合,从而阻断癌细胞的雌激素依赖性生长。

Mao, Chengjian; Patterson, Nicole M; Cherian, Milu T; Aninye, Irene O; Zhang, Chen; Montoya, Jamie Bonéy; Cheng, Jingwei; Putt, Karson S; Hergenrother, Paul J; Wilson, Elizabeth M; Nardulli, Ann M; Nordeen, Steven K; Shapiro, David J

Structure and sequence of the human fast skeletal troponin T (TNNT3) gene: insight into the evolution of the gene and the origin of the developmentally regulated isoforms

人类快速骨骼肌肌钙蛋白T(TNNT3)基因的结构和序列:深入了解该基因的进化以及发育调控亚型的起源

Stefancsik, Raymund; Randall, Jeffrey D; Mao, Chengjian; Sarkar, Satyapriya