日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

The paradox-breaking panRAF plus SRC family kinase inhibitor, CCT3833, is effective in mutant KRAS-driven cancers

CCT3833是一种打破悖论的泛RAF和SRC家族激酶抑制剂,对KRAS突变驱动的癌症有效。

Saturno, G; Lopes, F; Niculescu-Duvaz, I; Niculescu-Duvaz, D; Zambon, A; Davies, L; Johnson, L; Preece, N; Lee, R; Viros, A; Holovanchuk, D; Pedersen, M; McLeary, R; Lorigan, P; Dhomen, N; Fisher, C; Banerji, U; Dean, E; Krebs, M G; Gore, M; Larkin, J; Marais, R; Springer, C

Symptomatic hepatothorax presenting 25 years after penetrating thoracoabdominal injury

穿透性胸腹部损伤25年后出现症状性肝胸。

Variawa, S; Marais, R; Buitendag, Jjp; Edge, J; Steyn, E

Prediction and monitoring of relapse in stage III melanoma using circulating tumor DNA

利用循环肿瘤DNA预测和监测III期黑色素瘤的复发

Tan, L; Sandhu, S; Lee, R J; Li, J; Callahan, J; Ftouni, S; Dhomen, N; Middlehurst, P; Wallace, A; Raleigh, J; Hatzimihalis, A; Henderson, M A; Shackleton, M; Haydon, A; Mar, V; Gyorki, D E; Oudit, D; Dawson, M A; Hicks, R J; Lorigan, P; McArthur, G A; Marais, R; Wong, S Q; Dawson, S-J

Circulating tumor DNA predicts survival in patients with resected high-risk stage II/III melanoma

循环肿瘤DNA可预测接受切除术的高危II/III期黑色素瘤患者的生存期

Lee, R J; Gremel, G; Marshall, A; Myers, K A; Fisher, N; Dunn, J A; Dhomen, N; Corrie, P G; Middleton, M R; Lorigan, P; Marais, R

Plasma total cell-free DNA (cfDNA) is a surrogate biomarker for tumour burden and a prognostic biomarker for survival in metastatic melanoma patients

血浆总游离DNA(cfDNA)是肿瘤负荷的替代生物标志物,也是转移性黑色素瘤患者生存的预后生物标志物。

Valpione, S; Gremel, G; Mundra, P; Middlehurst, P; Galvani, E; Girotti, M R; Lee, R J; Garner, G; Dhomen, N; Lorigan, P C; Marais, R

A personalised medicine approach for ponatinib-resistant chronic myeloid leukaemia

针对帕纳替尼耐药性慢性粒细胞白血病的个体化治疗方案

Korfi, K; Mandal, A; Furney, S J; Wiseman, D; Somervaille, T C P; Marais, R

S338 phosphorylation of Raf-1 is independent of phosphatidylinositol 3-kinase and Pak3.

Raf-1 的 S338 磷酸化与磷脂酰肌醇 3-激酶和 Pak3 无关

Chiloeches A, Mason C S, Marais R

Serine and tyrosine phosphorylations cooperate in Raf-1, but not B-Raf activation

丝氨酸和酪氨酸磷酸化在Raf-1激活中协同作用,但不在B-Raf激活中协同作用。

Mason, C S; Springer, C J; Cooper, R G; Superti-Furga, G; Marshall, C J; Marais, R