日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Rescue of neuropsychiatric phenotypes in a mouse model of 16p11.2 duplication syndrome by genetic correction of an epilepsy network hub

通过对癫痫网络中心进行基因校正来挽救 16p11.2 重复综合征小鼠模型中的神经精神表型

Marc P Forrest, Marc Dos Santos, Nicolas H Piguel, Yi-Zhi Wang, Nicole A Hawkins, Vikram A Bagchi, Leonardo E Dionisio, Sehyoun Yoon, Dina Simkin, Maria Dolores Martin-de-Saavedra, Ruoqi Gao, Katherine E Horan, Alfred L George Jr, Mark S LeDoux, Jennifer A Kearney, Jeffrey N Savas, Peter Penzes

Multiple genes in a single GWAS risk locus synergistically mediate aberrant synaptic development and function in human neurons

单个 GWAS 风险位点中的多个基因协同介导人类神经元中异常的突触发育和功能

Siwei Zhang, Hanwen Zhang, Marc P Forrest, Yifan Zhou, Xiaotong Sun, Vikram A Bagchi, Alena Kozlova, Marc Dos Santos, Nicolas H Piguel, Leonardo E Dionisio, Alan R Sanders, Zhiping P Pang, Xin He, Peter Penzes, Jubao Duan

An IGFBP2-derived peptide promotes neuroplasticity and rescues deficits in a mouse model of Phelan-McDermid syndrome

IGFBP2 衍生肽可促进神经可塑性并挽救 Phelan-McDermid 综合征小鼠模型中的缺陷

Jeffrey S Burgdorf #, Sehyoun Yoon #, Marc Dos Santos, Catherine R Lammert, Joseph R Moskal, Peter Penzes

Early developmental deletion of forebrain Ank2 causes seizure-related phenotypes by reshaping the synaptic proteome

前脑 Ank2 的早期发育缺失通过重塑突触蛋白质组导致癫痫相关表型

Sehyoun Yoon, Marc Dos Santos, Marc P Forrest, Christopher P Pratt, Natalia Khalatyan, Peter J Mohler, Jeffrey N Savas, Peter Penzes

Intercellular signaling by ectodomain shedding at the synapse

突触处胞外域脱落介导的细胞间信号传导

Martín-de-Saavedra, M Dolores; Santos, Marc Dos; Penzes, Peter

Shed CNTNAP2 ectodomain is detectable in CSF and regulates Ca2+ homeostasis and network synchrony via PMCA2/ATP2B2

脱落的 CNTNAP2 胞外结构域可在 CSF 中检测到,并通过 PMCA2/ATP2B2 调节 Ca2+ 稳态和网络同步

M Dolores Martín-de-Saavedra, Marc Dos Santos, Lorenza Culotta, Olga Varea, Benjamin P Spielman, Euan Parnell, Marc P Forrest, Ruoqi Gao, Sehyoun Yoon, Emmarose McCoig, Hiba A Jalloul, Kristoffer Myczek, Natalia Khalatyan, Elizabeth A Hall, Liam S Turk, Antonio Sanz-Clemente, Davide Comoletti, Stefa

A developmental delay linked missense mutation in Kalirin-7 disrupts protein function and neuronal morphology

与发育迟缓相关的 Kalirin-7 错义突变会破坏蛋白质功能和神经元形态

Euan Parnell, Roos A Voorn, M Dolores Martin-de-Saavedra, Daniel D Loizzo, Marc Dos Santos, Peter Penzes

Exploiting Interdata Relationships in Prostate Cancer Proteomes: Clinical Significance of HO-1, HSPB1, DDB1 and 14-3-3ζ/δ Interaction

利用前列腺癌蛋白质组中的数据间关系:HO-1、HSPB1、DDB1 和 14-3-3ζ/δ 相互作用的临床意义

Santos, Marc Dos; Forrest, Marc P; Bomba-Warczak, Ewa; Parnell, Euan; Edassery, Seby L; Yang, Kun; Hayes, Lindsay N; Coughlin, Jennifer M; Eckman, Blair L; Lammert, Catherine; Martin-de-Saavedra, M Dolores; Barbolina, Maria; Sawa, Akira; Savas, Jeffrey N; Penzes, Peter; Lage-Vickers, Sofia; Sanchis, Pablo; Bizzotto, Juan; Toro, Ayelen; Valacco, Maria P; Cotignola, Javier; Vazquez, Elba; Gueron, Geraldine

Putaminal diffusion tensor imaging measures predict disease severity across human prion diseases

壳核弥散张量成像测量值可预测人类朊病毒疾病的严重程度

Hyare, Harpreet; De Vita, Enrico; Porter, Marie-Claire; Simpson, Ivor; Ridgway, Gerard; Lowe, Jessica; Thompson, Andrew; Carswell, Chris; Ourselin, Sebastien; Modat, Marc; Dos Santos Canas, Liane; Caine, Diana; Fox, Zoe; Rudge, Peter; Collinge, John; Mead, Simon; Thornton, John S