日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Synthetic lethality of TNK2 inhibition in PTPN11-mutant leukemia

TNK2 抑制对 PTPN11 突变白血病的综合致死率

Chelsea Jenkins, Samuel B Luty, Julia E Maxson, Christopher A Eide, Melissa L Abel, Corinne Togiai, Eneida R Nemecek, Daniel Bottomly, Shannon K McWeeney, Beth Wilmot, Marc Loriaux, Bill H Chang, Jeffrey W Tyner

YM155 potently kills acute lymphoblastic leukemia cells through activation of the DNA damage pathway

YM155 通过激活 DNA 损伤通路有效杀死急性淋巴细胞白血病细胞

Bill H Chang, Kara Johnson, Dorian LaTocha, Joelle S J Rowley, Jade Bryant, Russell Burke, Rebecca L Smith, Marc Loriaux, Markus Müschen, Charles Mullighan, Brian J Druker, Jeffrey W Tyner

Imatinib and Dasatinib Inhibit Hemangiosarcoma and Implicate PDGFR-β and Src in Tumor Growth

伊马替尼和达沙替尼可抑制血管肉瘤,并暗示 PDGFR-β 和 Src 与肿瘤生长有关

Erin B Dickerson, Kevin Marley, Wade Edris, Jeffrey W Tyner, Vidya Schalk, Valerie Macdonald, Marc Loriaux, Brian J Druker, Stuart C Helfand

Effects of plerixafor in combination with BCR-ABL kinase inhibition in a murine model of CML

普乐沙福联合 BCR-ABL 激酶抑制剂对小鼠 CML 模型的影响

Anupriya Agarwal, Angela G Fleischman, Curtis L Petersen, Ryan MacKenzie, Samuel Luty, Marc Loriaux, Brian J Druker, Randall L Woltjer, Michael W Deininger

A BCR-ABL mutant lacking direct binding sites for the GRB2, CBL and CRKL adapter proteins fails to induce leukemia in mice

缺乏 GRB2、CBL 和 CRKL 衔接蛋白直接结合位点的 BCR-ABL 突变体无法在小鼠中诱发白血病

Kara J Johnson, Ian J Griswold, Thomas O'Hare, Amie S Corbin, Marc Loriaux, Michael W Deininger, Brian J Druker

Absence of SKP2 expression attenuates BCR-ABL-induced myeloproliferative disease

SKP2表达缺失可减弱BCR-ABL诱导的骨髓增生性疾病

Anupriya Agarwal ,Thomas G P Bumm, Amie S Corbin, Thomas O'Hare, Marc Loriaux, Jonathan VanDyke, Stephanie G Willis, Jutta Deininger, Keiichi I Nakayama, Brian J Druker, Michael W Deininger