日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

SUMOylation inhibitor TAK-981 (subasumstat) synergizes with 5-azacytidine in preclinical models of acute myeloid leukemia

SUMOylation 抑制剂 TAK-981(subasumstat)与 5-氮杂胞苷在急性髓系白血病临床前模型中发挥协同作用

Ludovic Gabellier, Marion De Toledo, Mehuli Chakraborty, Dana Akl, Rawan Hallal, Mays Aqrouq, Giovanni Buonocore, Clara Recasens-Zorzo, Guillaume Cartron, Abigaïl Delort, Marc Piechaczyk, Denis Tempé, Guillaume Bossis

Multiple Fra-1-bound enhancers showing different molecular and functional features can cooperate to repress gene transcription

多个具有不同分子和功能特征的Fra-1结合增强子可以协同抑制基因转录

Fabienne Bejjani # ,Emilie Evanno # ,Samantha Mahfoud # ,Claire Tolza # ,Kazem Zibara ,Marc Piechaczyk # ,Isabelle Jariel-Encontre #

New roles for AP-1/JUNB in cell cycle control and tumorigenic cell invasion via regulation of cyclin E1 and TGF-β2

AP-1/JUNB通过调节细胞周期蛋白E1和TGF-β2在细胞周期控制和致瘤细胞侵袭中的新作用

Beatriz Pérez-Benavente #, Alihamze Fathinajafabadi #, Lorena de la Fuente, Carolina Gandía, Arantxa Martínez-Férriz, José Miguel Pardo-Sánchez, Lara Milián, Ana Conesa, Octavio A Romero, Julián Carretero, Rune Matthiesen, Isabelle Jariel-Encontre #, Marc Piechaczyk #, Rosa Farràs

Fra-1 regulates its target genes via binding to remote enhancers without exerting major control on chromatin architecture in triple negative breast cancers

Fra-1通过与远端增强子结合来调控其靶基因,但并不对三阴性乳腺癌的染色质结构发挥主要控制作用。

Fabienne Bejjani ,Claire Tolza ,Mathias Boulanger ,Damien Downes ,Raphaël Romero ,Muhammad Ahmad Maqbool ,Amal Zine El Aabidine ,Jean-Christophe Andrau ,Sophie Lebre ,Laurent Brehelin ,Hughes Parrinello ,Marine Rohmer ,Tony Kaoma ,Laurent Vallar ,Jim R Hughes ,Kazem Zibara ,Charles-Henri Lecellier ,Marc Piechaczyk ,Isabelle Jariel-Encontre

Ubiquitin and SUMO conjugation as biomarkers of acute myeloid leukemias response to chemotherapies

泛素和 SUMO 结合作为急性髓系白血病对化疗反应的生物标志物

Pierre Gâtel, Frédérique Brockly, Christelle Reynes, Manuela Pastore, Yosr Hicheri, Guillaume Cartron, Marc Piechaczyk, Guillaume Bossis

Neutrophils are essential for induction of vaccine-like effects by antiviral monoclonal antibody immunotherapies

中性粒细胞对于抗病毒单克隆抗体免疫疗法诱导疫苗样效应至关重要

Mar Naranjo-Gomez, Jennifer Lambour, Marc Piechaczyk, Mireia Pelegrin

c-Fos Protects Neurons Through a Noncanonical Mechanism Involving HDAC3 Interaction: Identification of a 21-Amino Acid Fragment with Neuroprotective Activity

c-Fos 通过涉及 HDAC3 相互作用的非典型机制保护神经元:鉴定具有神经保护活性的 21 个氨基酸片段

Varun Rawat, Warren Goux, Marc Piechaczyk, Santosh R D Mello

Transcriptional complexity and roles of Fra-1/AP-1 at the uPA/Plau locus in aggressive breast cancer

uPA/Plau 基因座中 Fra-1/AP-1 在侵袭性乳腺癌中的转录复杂性及其作用

Gabriel Moquet-Torcy, Claire Tolza, Marc Piechaczyk, Isabelle Jariel-Encontre

Chromatin loop organization of the junb locus in mouse dendritic cells

小鼠树突状细胞中 junb 基因座的染色质环组织

Tamara Salem, Tiphanie Gomard, Franck Court, Gabriel Moquet-Torcy, Frédérique Brockly, Thierry Forné, Marc Piechaczyk

Long-lasting protective antiviral immunity induced by passive immunotherapies requires both neutralizing and effector functions of the administered monoclonal antibody

被动免疫疗法诱导的持久性保护性抗病毒免疫需要所施用的单克隆抗体同时具备中和功能和效应功能。

Nasser, Roudaina; Pelegrin, Mireia; Michaud, Henri-Alexandre; Plays, Marc; Piechaczyk, Marc; Gros, Laurent