日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Loss of RET Promotes Mesenchymal Identity in Neuroblastoma Cells

RET 的缺失促进神经母细胞瘤细胞的间充质身份

Joachim T Siaw, Jonatan L Gabre, Ezgi Uçkun, Marc Vigny, Wancun Zhang, Jimmy Van den Eynden, Bengt Hallberg, Ruth H Palmer, Jikui Guan

Tumor Antigen and Receptor Densities Regulate Efficacy of a Chimeric Antigen Receptor Targeting Anaplastic Lymphoma Kinase

肿瘤抗原和受体密度调节针对间变性淋巴瘤激酶的嵌合抗原受体的功效

Alec J Walker, Robbie G Majzner, Ling Zhang, Kelsey Wanhainen, Adrienne H Long, Sang M Nguyen, Paola Lopomo, Marc Vigny, Terry J Fry, Rimas J Orentas, Crystal L Mackall

Characterization of rearrangements involving the ALK gene reveals a novel truncated form associated with tumor aggressiveness in neuroblastoma

ALK 基因重排的表征揭示了一种与神经母细胞瘤肿瘤侵袭性相关的新型截短形式

Alex Cazes, Caroline Louis-Brennetot, Pierre Mazot, Florent Dingli, Bérangère Lombard, Valentina Boeva, Romain Daveau, Julie Cappo, Valérie Combaret, Gudrun Schleiermacher, Stéphanie Jouannet, Sandrine Ferrand, Gaëlle Pierron, Emmanuel Barillot, Damarys Loew, Marc Vigny, Olivier Delattre, Isabelle J

Internalization and down-regulation of the ALK receptor in neuroblastoma cell lines upon monoclonal antibodies treatment

单克隆抗体治疗后神经母细胞瘤细胞系中 ALK 受体的内化和下调

Pierre Mazot, Alex Cazes, Florent Dingli, Joffrey Degoutin, Théano Irinopoulou, Marie-Claude Boutterin, Bérangère Lombard, Damarys Loew, Bengt Hallberg, Ruth Helen Palmer, Olivier Delattre, Isabelle Janoueix-Lerosey, Marc Vigny

The neuroblastoma ALK(I1250T) mutation is a kinase-dead RTK in vitro and in vivo

神经母细胞瘤 ALK(I1250T) 突变在体外和体内均是一种激酶失活 RTK

Christina Schönherr, Kristina Ruuth, Therese Eriksson, Yasuo Yamazaki, Christian Ottmann, Valerie Combaret, Marc Vigny, Sattu Kamaraj, Ruth H Palmer, Bengt Hallberg

Anaplastic lymphoma kinase is a dependence receptor whose proapoptotic functions are activated by caspase cleavage

间变性淋巴瘤激酶是一种依赖性受体,其促凋亡功能由 caspase 裂解激活

Jaouhar Mourali, Alan Bénard, Filipe Calheiros Lourenço, Céline Monnet, Catherine Greenland, Christel Moog-Lutz, Claire Racaud-Sultan, Daniel Gonzalez-Dunia, Marc Vigny, Patrick Mehlen, Georges Delsol, Michèle Allouche