Pre-clinical animal models are poor predictors of human toxicities in phase 1 oncology clinical trials
临床前动物模型对预测I期肿瘤临床试验中的人体毒性效果不佳。
期刊:British Journal of Cancer
影响因子:6.8
doi:10.1038/s41416-020-01033-x
Atkins, Johnique T; George, Goldy C; Hess, Kenneth; Marcelo-Lewis, Kathrina L; Yuan, Ying; Borthakur, Gautam; Khozin, Sean; LoRusso, Patricia; Hong, David S