Marchant Jonathan S相关文献与解析，生知库 | 链接生命科学的每一步

日期影响因子

Novel 1H-1,2,3-Triazole Derivatives of Praziquantel with TRPM(PZQ) Modulatory Activity and Antiparasitic Effects on Larvae, Juvenile, and Adult Worms of Schistosoma mansoni

新型吡喹酮1H-1,2,3-三唑衍生物及其对曼氏血吸虫幼虫、幼虫和成虫的TRPM(PZQ)调节活性和抗寄生虫作用

期刊:ACS Infectious Diseases

影响因子:3.8

doi:10.1021/acsinfecdis.5c00914

Junior, Floriano Paes Silva; Dantas, Rafael Ferreira; Park, Sang-Kyu; Whiteland, Helen; Oliveira, Camilla Thomaz da Silva; Rezende-Neto, João M; Reis, Jordano Ferreira; Forde-Thomas, Josephine; Gomes, Luciano Pinho; Valente, Walter C G; Schirato, Giuliana Viegas; Noronha, Frederico Ricardo de Castro Jr; Hoffmann, Karl F; Marchant, Jonathan S; Ferreira, Sabrina Baptista

发表日期：2026

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TRPtracker: a community database for monitoring praziquantel sensitivity at TRPM(PZQ) variants

TRPtracker：一个用于监测TRPM(PZQ)变异株吡喹酮敏感性的社区数据库

期刊:International Journal for Parasitology-Drugs and Drug Resistance

影响因子:3.4

doi:10.1016/j.ijpddr.2026.100639

Rohr, Claudia M; Park, Sang-Kyu; Aguiar-Martins, Kelsilandia; Anderson, Timothy J C; Berger, Duncan J; Berriman, Matthew; Buddenborg, Sarah K; Bustinduy, Amaya L; Chevalier, Frédéric D; Cotton, James A; Crellen, Thomas; Doyle, Stephen R; Emery, Aidan M; Kincaid Smith, Julien; Kinung'hi, Safari; Lamberton, Poppy H L; Le Clec'h, Winka; Ndombi, Eric; Pennance, Tom; Rowel, Candia; Summers, Shannan S; Tushabe, John Vianney; Walker, Martin; Webster, Bonnie L; Webster, Joanne P; Wilson, Shona; Marchant, Jonathan S

发表日期：2026

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Meclonazepam sensitivity of parasitic flatworms correlates with TRPM(MCLZ) sensitivity to meclonazepam

寄生扁形动物对美氯硝西泮的敏感性与TRPM(MCLZ)对美氯硝西泮的敏感性相关

期刊:International Journal for Parasitology-Drugs and Drug Resistance

影响因子:3.4

doi:10.1016/j.ijpddr.2026.100634

Rohr, Claudia M; McCusker, Paul; Kaethner, Marc; Armstrong, Rebecca; Robb, Emily; Park, Sang-Kyu; Sprague, Daniel J; Maule, Aaron G; Zamanian, Mostafa; Lundström-Stadelmann, Britta; Chan, John D; Marchant, Jonathan S

发表日期：2026

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Clonazepam activates the transient receptor potential melastatin 8 (TRPM8) ion channel

氯硝西泮激活瞬时受体电位melastatin 8 (TRPM8)离子通道

doi:10.64898/2026.01.19.700423

Elkin, Logan; Chulkov, Evgeny G; Enders, Jonathan; Menzel, Anthony D; Park, Sang-Kyu; Stucky, Cheryl L; Marchant, Jonathan S

发表日期：2026

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Liquid liquid phase separation of the intrinsically disordered protein JPT2 compartmentalizes components of NAADP-evoked Ca(2+) signaling

固有无序蛋白JPT2的液液相分离将NAADP诱发的Ca(2+)信号传导的成分分隔开来

doi:10.64898/2026.01.10.698830

Kumar, Sushil; Gunaratne, Gihan S; Cornish, Jasmine; Silvey, Kirsten M; Mu, Qianru; Guan, Zhong; Heller, Gabriella T; Slama, James T; Patel, Sandip; Marchant, Jonathan S

发表日期：2026

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Target-Based Design of Praziquantel Analogs at Cestode TRPM(PZQ)

基于靶点的吡喹酮类似物设计（针对绦虫 TRPM(PZQ)）

期刊:ACS Infectious Diseases

影响因子:3.8

doi:10.1021/acsinfecdis.5c00449

Sprague, Daniel J; Park, Sang-Kyu; Kaethner, Marc; Rohr, Claudia M; Ghobrial, Mina R; Barth, D Connor; Maillard, David; Spangenberg, Thomas; Lundström-Stadelmann, Britta; Marchant, Jonathan S

发表日期：2025

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TRPtracker: a community database for monitoring praziquantel sensitivity at TRPM(PZQ) variants

TRPtracker：一个用于监测TRPM(PZQ)变异株吡喹酮敏感性的社区数据库

doi:10.1101/2025.08.27.671753

Rohr, Claudia M; Park, Sang-Kyu; Aguiar-Martins, Kelsilandia; Anderson, Timothy J C; Berger, Duncan J; Berriman, Matthew; Buddenborg, Sarah K; Bustinduy, Amaya L; Chevalier, Frédéric D; Cotton, James A; Crellen, Thomas; Doyle, Stephen R; Emery, Aidan M; Smith, Julien Kincaid; Kinung'hi, Safari; Lamberton, Poppy H L; Le Clec'h, Winka; Ndombi, Eric; Pennance, Tom; Rowel, Candia; Summers, Shannan S; Tushabe, John Vianney; Walker, Martin; Webster, Bonnie L; Webster, Joanne P; Wilson, Shona; Marchant, Jonathan S

发表日期：2025

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Target-based discovery of a broad-spectrum flukicide.

基于靶点的广谱杀吸虫剂的发现

期刊:Nature Structural & Molecular Biology

影响因子:10.1

doi:10.1038/s41594-024-01298-3

Sprague Daniel J, Park Sang-Kyu, Gramberg Svenja, Bauer Lisa, Rohr Claudia M, Chulkov Evgeny G, Smith Emery, Scampavia Louis, Spicer Timothy P, Haeberlein Simone, Marchant Jonathan S

发表日期：2024

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The anthelmintic meclonazepam activates a schistosome transient receptor potential channel

驱虫药美氯硝西泮可激活血吸虫瞬时受体电位通道。

期刊:Journal of Biological Chemistry

影响因子:3.9

doi:10.1016/j.jbc.2023.105528

Park, Sang-Kyu; Sprague, Daniel J; Rohr, Claudia M; Chulkov, Evgeny G; Petrow, Ian; Kumar, Sushil; Marchant, Jonathan S

发表日期：2024

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Diazirine-AIOC-NAADP, a Clickable-Photoactive NAADP Analog for Sea Urchin NAADP Binding Proteins.

二氮杂环丙烯-AIOC-NAADP，一种可点击的光敏NAADP类似物，用于海胆NAADP结合蛋白

期刊:ACS Chemical Biology

影响因子:3.8

doi:10.1021/acschembio.4c00425

Zhang Yuqing, Guan Zhong, Gadient Jennifer N, Kumar Sushil, Gunaratne Gihan, Walseth Timothy F, Marchant Jonathan S, Wall Katherine A, Slama James T

免疫/内分泌

发表日期：2024

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