日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

The combined use of scRNA-seq and network propagation highlights key features of pan-cancer Tumor-Infiltrating T cells

单细胞RNA测序与网络传播的联合应用突显了泛癌肿瘤浸润T细胞的关键特征。

Mangelinck, Adèle; Molitor, Elodie; Marchiq, Ibtissam; Alaoui, Lamine; Bouaziz, Matthieu; Andrade-Pereira, Renan; Darville, Hélène; Becht, Etienne; Lefebvre, Céline

UCART19, a first-in-class allogeneic anti-CD19 chimeric antigen receptor T-cell therapy for adults with relapsed or refractory B-cell acute lymphoblastic leukaemia (CALM): a phase 1, dose-escalation trial

UCART19 是一种首创的同种异体抗 CD19 嵌合抗原受体 T 细胞疗法,用于治疗复发或难治性 B 细胞急性淋巴细胞白血病 (CALM) 成人患者:一项 1 期剂量递增试验

Benjamin, Reuben; Jain, Nitin; Maus, Marcela V; Boissel, Nicolas; Graham, Charlotte; Jozwik, Agnieszka; Yallop, Deborah; Konopleva, Marina; Frigault, Matthew J; Teshima, Takanori; Kato, Koji; Boucaud, Floriane; Balandraud, Svetlana; Gianella-Borradori, Athos; Binlich, Florence; Marchiq, Ibtissam; Dupouy, Sandra; Almena-Carrasco, Maria; Pannaux, Matthieu; Fouliard, Sylvain; Brissot, Eolia; Mohty, Mohamad

Time to evolve: predicting engineered T cell-associated toxicity with next-generation models

变革的时代:利用新一代模型预测工程化T细胞相关毒性

Donnadieu, Emmanuel; Luu, Maik; Alb, Miriam; Anliker, Brigitte; Arcangeli, Silvia; Bonini, Chiara; De Angelis, Biagio; Choudhary, Rashmi; Espie, David; Galy, Anne; Holland, Cam; Ivics, Zoltán; Kantari-Mimoun, Chahrazade; Kersten, Marie Jose; Köhl, Ulrike; Kuhn, Chantal; Laugel, Bruno; Locatelli, Franco; Marchiq, Ibtissam; Markman, Janet; Moresco, Marta Angiola; Morris, Emma; Negre, Helene; Quintarelli, Concetta; Rade, Michael; Reiche, Kristin; Renner, Matthias; Ruggiero, Eliana; Sanges, Carmen; Stauss, Hans; Themeli, Maria; Van den Brulle, Jan; Hudecek, Michael; Casucci, Monica

Time 2EVOLVE: predicting efficacy of engineered T-cells - how far is the bench from the bedside?

Time 2EVOLVE:预测工程化 T 细胞的疗效——实验室研究距离临床应用还有多远?

Guedan, Sonia; Luu, Maik; Ammar, Delphine; Barbao, Paula; Bonini, Chiara; Bousso, Philippe; Buchholz, Christian J; Casucci, Monica; De Angelis, Biagio; Donnadieu, Emmanuel; Espie, David; Greco, Beatrice; Groen, Richard; Huppa, Johannes B; Kantari-Mimoun, Chahrazade; Laugel, Bruno; Mantock, Mary; Markman, Janet L; Morris, Emma; Quintarelli, Concetta; Rade, Michael; Reiche, Kristin; Rodriguez-Garcia, Alba; Rodriguez-Madoz, Juan Roberto; Ruggiero, Eliana; Themeli, Maria; Hudecek, Michael; Marchiq, Ibtissam

Mechanistic Modeling of the Interplay Between Host Immune System, IL-7 and UCART19 Allogeneic CAR-T Cells in Adult B-cell Acute Lymphoblastic Leukemia

成人B细胞急性淋巴细胞白血病中宿主免疫系统、IL-7和UCART19同种异体CAR-T细胞相互作用的机制模型

Derippe, Thibaud; Fouliard, Sylvain; Marchiq, Ibtissam; Dupouy, Sandra; Almena-Carrasco, Maria; Geronimi, Julia; Declèves, Xavier; Chenel, Marylore; Mager, Donald E

Clinical Pharmacology and Determinants of Response to UCART19, an Allogeneic Anti-CD19 CAR-T Cell Product, in Adult B-cell Acute Lymphoblastic Leukemia

成人 B 细胞急性淋巴细胞白血病对同种异体抗 CD19 CAR-T 细胞产品 UCART19 的临床药理学和反应决定因素

Sandra Dupouy, Ibtissam Marchiq, Thibaud Derippe, Maria Almena-Carrasco, Agnieszka Jozwik, Sylvain Fouliard, Yasmina Adimy, Julia Geronimi, Charlotte Graham, Nitin Jain, Marcela V Maus, Mohamad Mohty, Nicolas Boissel, Takanori Teshima, Koji Kato, Reuben Benjamin, Svetlana Balandraud

Genome-edited, donor-derived allogeneic anti-CD19 chimeric antigen receptor T cells in paediatric and adult B-cell acute lymphoblastic leukaemia: results of two phase 1 studies

基因编辑的供体来源异基因抗CD19嵌合抗原受体T细胞治疗儿童和成人B细胞急性淋巴细胞白血病:两项I期研究的结果

Benjamin, Reuben; Graham, Charlotte; Yallop, Deborah; Jozwik, Agnieszka; Mirci-Danicar, Oana C; Lucchini, Giovanna; Pinner, Danielle; Jain, Nitin; Kantarjian, Hagop; Boissel, Nicolas; Maus, Marcela V; Frigault, Matthew J; Baruchel, André; Mohty, Mohamad; Gianella-Borradori, Athos; Binlich, Florence; Balandraud, Svetlana; Vitry, Fabien; Thomas, Elisabeth; Philippe, Anne; Fouliard, Sylvain; Dupouy, Sandra; Marchiq, Ibtissam; Almena-Carrasco, Maria; Ferry, Nicolas; Arnould, Sylvain; Konto, Cyril; Veys, Paul; Qasim, Waseem

Optimized Protocol for the In Situ Derivatization of Glutathione with N-Ethylmaleimide in Cultured Cells and the Simultaneous Determination of Glutathione/Glutathione Disulfide Ratio by HPLC-UV-QTOF-MS

谷胱甘肽与 N-乙基马来酰亚胺在培养细胞中的原位衍生化优化方案及通过 HPLC-UV-QTOF-MS 同时测定谷胱甘肽/谷胱甘肽二硫键比率

Xueni Sun, Raffaela S Berger, Paul Heinrich, Ibtissam Marchiq, Jacques Pouyssegur, Kathrin Renner, Peter J Oefner, Katja Dettmer

Metabolic Plasiticy in Cancers-Distinct Role of Glycolytic Enzymes GPI, LDHs or Membrane Transporters MCTs

癌症中的代谢可塑性——糖酵解酶GPI、LDH或膜转运蛋白MCT的独特作用

Ždralević, Maša; Marchiq, Ibtissam; de Padua, Monique M Cunha; Parks, Scott K; Pouysségur, Jacques

Knock out of the BASIGIN/CD147 chaperone of lactate/H+ symporters disproves its pro-tumour action via extracellular matrix metalloproteases (MMPs) induction

敲除乳酸/H+ 同向转运体的 BASIGIN/CD147 伴侣分子,可反驳其通过细胞外基质金属蛋白酶 (MMP) 诱导发挥的促肿瘤作用

Ibtissam Marchiq, Jean Albrengues, Sara Granja, Cédric Gaggioli, Jacques Pouysségur, Marie-Pierre Simon