日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Env-antibody coevolution identifies B cell priming as the principal bottleneck to HIV V2 apex broadly neutralizing antibody development.

Env抗体共同进化表明B细胞启动是HIV V2顶端广泛中和抗体发展的主要瓶颈。

Habib Rumi, Roark Ryan S, Li Hui, Connell Andrew Jesse, Hogarty Michael P, Wagh Kshitij, Wang Shuyi, Marchitto Lorie, Skelly Ashwin N, Carey John W, Sowers Kirsten J, Ayyanathan Kasirajan, Plante Samantha J, Bibollet-Ruche Frederic, Park Younghoon, Agostino Colby J, Singh Ajay, Martella Christian L, Lewis Emily, Rando Juliette M, Chohan Neha, Lora Jinery, Ding Wenge, Campion Mary S, Zhao Chengyan, Liu Weimin, Li Yingying, Li Xuduo, Liang Bo, Chowdhury Rohan Roy, Amereh Khaled, Van Itallie Elizabeth, Sheng Zizhang, Ghosh Amrit R, Bar Katharine J, Williams Wilton B, Wiehe Kevin, Saunders Kevin O, Edwards Robert J, Cain Derek W, Lewis Mark G, Batista Facundo D, Burton Dennis R, Andrabi Raiees, Kulp Daniel W, Haynes Barton F, Korber Bette, Shapiro Lawrence, Kwong Peter D, Hahn Beatrice H, Shaw George M

Shared Maturation Pathways of HIV-1 Envelope-reactive V3-glycan bnAb Lineages in Human and Rhesus Macaque

人类和恒河猴中 HIV-1 包膜反应性 V3 聚糖广谱中和抗体谱系的共同成熟途径

Clark, Matthew; Li, Hui; Martin, Mitchell; Evangelous, Tyler D; Gobeil, Sophie M-C; Berry, Madison; Wagh, Kshitij; Giorgi, Elena E; Hogarty, Michael P; Zhao, Chengyan; Wang, Shuyi; Marchitto, Lorie; Ding, Wenge; Park, Younghoon; Rando, Juliette; Carey, John; Connell, Andrew J; Skelly, Ashwin N; Chen, Yue; Rohr, Seth; Jiang, Chuancang; Venkatayogi, Sravani; Mansouri, Katayoun; Edwards, Robert J; Lindenberger, Jared; Hora, Bhavna; Doria-Rose, Nicole; Mascola, John; van Gils, Marit J; Sanders, Rogier W; Korber, Bette; Hahn, Beatrice; Saunders, Kevin O; Acharya, Priyamvada; Wiehe, Kevin; Haynes, Barton F; Shaw, George M; Williams, Wilton B

The asymmetric opening of HIV-1 Env by a potent CD4 mimetic enables anti-coreceptor binding site antibodies to mediate ADCC

强效CD4模拟物对HIV-1 Env的不对称打开作用,使得抗辅助受体结合位点抗体能够介导抗体依赖性细胞毒性作用(ADCC)。

Richard, Jonathan; Grunst, Michael W; Niu, Ling; Díaz-Salinas, Marco A; Zhu, Li; Tolbert, William D; Marchitto, Lorie; Zhou, Fei; Bourassa, Catherine; Kim, Hongil; Boodapati, Sri Lakshmi Tejaswi; Yang, Derek; Chiu, Ta Jung; Chen, Hung-Ching; Benlarbi, Mehdi; Beaudoin-Bussières, Guillaume; Gottumukkala, Suneetha; Li, Wenwei; Dionne, Katrina; Bélanger, Étienne; Chatterjee, Debashree; Medjahed, Halima; Hendrickson, Wayne A; Sodroski, Joseph; Lang, Zabrina C; Morton, Abraham J; Huang, Rick K; Matthies, Doreen; Smith, Amos B 3rd; Kumar, Priti; Mothes, Walther; Munro, James B; Pazgier, Marzena; Finzi, Andrés

Env-antibody coevolution identifies B cell priming as the principal bottleneck to HIV-1 V2 apex broadly neutralizing antibody development

Env抗体协同进化研究表明,B细胞启动是HIV-1 V2顶端广谱中和抗体产生的主要瓶颈。

Habib, Rumi; Roark, Ryan S; Li, Hui; Connell, Andrew Jesse; Hogarty, Michael P; Wagh, Kshitij; Wang, Shuyi; Marchitto, Lorie; Skelly, Ashwin N; Carey, John W; Sowers, Kirsten J; Ayyanathan, Kasirajan; Plante, Samantha J; Bibollet-Ruche, Frederic; Park, Younghoon; Agostino, Colby J; Singh, Ajay; Martella, Christian L; Lewis, Emily; Rando, Juliette M; Chohan, Neha; Lora, Jinery; Ding, Wenge; Campion, Mary S; Zhao, Chengyan; Liu, Weimin; Li, Yingying; Li, Xuduo; Liang, Bo; Chowdhury, Rohan Roy; Amereh, Khaled; Van Itallie, Elizabeth; Sheng, Zizhang; Ghosh, Amrit R; Bar, Katharine J; Williams, Wilton B; Wiehe, Kevin; Saunders, Kevin O; Edwards, Robert J; Cain, Derek W; Lewis, Mark; Batista, Facundo D; Burton, Dennis R; Andrabi, Raiees; Kulp, Daniel W; Haynes, Barton F; Korber, Bette; Shapiro, Lawrence; Kwong, Peter D; Hahn, Beatrice H; Shaw, George M

Consistent Induction of Broadly Neutralizing HIV Antibodies by a Novel Two-Step Mechanism Informs Immunogen Design

通过一种新型两步机制持续诱导广谱中和HIV抗体,为免疫原设计提供指导

Skelly, Ashwin N; Gristick, Harry B; Li, Hui; Gavor, Edem; Connell, Andrew J; Kreider, Edward F; Marchitto, Lorie; Hogarty, Michael P; Newby, Maddy L; Allen, Joel D; Liu, Weimin; West, Anthony P Jr; Ayyanathan, Kasirajan; Campion, Mary S; Winters, Kaitlyn; Gordon, Colette G; Osbaldeston, Rebecca A; Akeley, Macy J; Li, Yingying; Singh, Ajay; Cruickshank, Kendra; Park, Younghoon; Zhao, Chengyan; Li, Xuduo; Amereh, Khaled; Itallie, Elizabeth Van; Carey, John W; Albertus, Amie; DeLaitsch, Andrew T; Keeffe, Jennifer R; Lituchy, Melinda G; Walsh, Agnes A; Morris, Daniel J; Habib, Rumi; Bibollet-Ruche, Frederic; Mishra, Nitesh; Avillion, Gabriel; Koranda, Nicholas S; Plante, Samantha J; Martella, Christian L; Lora, Jinery; Wang, Eric J D; Lewis, Mark G; Martin, Malcolm A; Nussenzweig, Michel C; Seaman, Michael S; Irvine, Darrell J; Wiehe, Kevin J; Haynes, Barton F; Wagh, Kshitij; Korber, Bette T; Andrabi, Raiees; Crispin, Max; Weissman, Drew; Bjorkman, Pamela J; Hahn, Beatrice H; Shaw, George M

Impact of Prolonged SARS-CoV-2 Dosing Interval in Hemodialysis Patients

延长SARS-CoV-2给药间隔对血液透析患者的影响

Lamarche, Caroline; Tennankore, Karthik; Marchitto, Lorie; Beabien-Souligny, William; Goupil, Rémi; Nadeau-Fredette, Annie-Claire; Gunaratnam, Lakshman; Mac-Way, Fabrice; Benlarbi, Mehdi; Chatterjee, Debashree; Tom, Alexander; Medjahed, Halima; Kaufmann, Daniel E; Finzi, Andrés; Suri, Rita S

Humoral Responses Elicited by SARS-CoV-2 mRNA Vaccine in People Living with HIV

HIV感染者接种SARS-CoV-2 mRNA疫苗后产生的体液免疫反应

Marchitto, Lorie; Chatterjee, Debashree; Ding, Shilei; Gendron-Lepage, Gabrielle; Tauzin, Alexandra; Boutin, Marianne; Benlarbi, Mehdi; Medjahed, Halima; Sylla, Mohamed; Lanctôt, Hélène; Durand, Madeleine; Finzi, Andrés; Tremblay, Cécile

Temsavir Treatment of HIV-1-Infected Cells Decreases Envelope Glycoprotein Recognition by Broadly Neutralizing Antibodies

替姆沙韦治疗HIV-1感染细胞可降低广谱中和抗体对包膜糖蛋白的识别

Boutin, Marianne; Vézina, Dani; Ding, Shilei; Prévost, Jérémie; Laumaea, Annemarie; Marchitto, Lorie; Anand, Sai Priya; Medjahed, Halima; Gendron-Lepage, Gabrielle; Bourassa, Catherine; Goyette, Guillaume; Clark, Andrew; Richard, Jonathan; Finzi, Andrés

Covid-19 vaccine immunogenicity in people living with HIV-1

新冠病毒疫苗在 HIV-1 感染者中的免疫原性

Nault, Lauriane; Marchitto, Lorie; Goyette, Guillaume; Tremblay-Sher, Daniel; Fortin, Claude; Martel-Laferrière, Valérie; Trottier, Benoît; Richard, Jonathan; Durand, Madeleine; Kaufmann, Daniel; Finzi, Andrés; Tremblay, Cécile

Temporal associations of B and T cell immunity with robust vaccine responsiveness in a 16-week interval BNT162b2 regimen.

在 16 周间隔的 BNT162b2 方案中,B 细胞和 T 细胞免疫与强大的疫苗反应性存在时间关联

Nayrac Manon, Dubé Mathieu, Sannier Gérémy, Nicolas Alexandre, Marchitto Lorie, Tastet Olivier, Tauzin Alexandra, Brassard Nathalie, Beaudoin-Bussières Guillaume, Vézina Dani, Gong Shang Yu, Benlarbi Mehdi, Gasser Romain, Laumaea Annemarie, Bourassa Catherine, Gendron-Lepage Gabrielle, Medjahed Halima, Goyette Guillaume, Ortega-Delgado Gloria-Gabrielle, Laporte Mélanie, Niessl Julia, Gokool Laurie, Morrisseau Chantal, Arlotto Pascale, Richard Jonathan, Tremblay Cécile, Martel-Laferrière Valérie, Finzi Andrés, Kaufmann Daniel E