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日期影响因子

Delayed recanalization reduced neuronal apoptosis and neurological deficits by enhancing liver-derived trefoil factor 3-mediated neuroprotection via LINGO2/EGFR/Src signaling pathway after middle cerebral artery occlusion in rats

大鼠大脑中动脉闭塞后延迟再通可通过增强肝源性三叶因子 3 通过 LINGO2/EGFR/Src 信号通路介导的神经保护作用来减少神经元凋亡和神经功能缺损

期刊:Experimental Neurology

影响因子:4.6

doi:10.1016/j.expneurol.2023.114607

Dujuan Li, Lifei Lian, Lei Huang, Marcin Gamdzyk, Yi Huang, Desislava Doycheva, Gaigai Li, Shufeng Yu, Yong Guo, Ruiqing Kang, Hong Tang, Jiping Tang, Lingfei Kong, John H Zhang

发表日期：2024

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Three Days Delayed Recanalization Improved Neurological Function in pMCAO Rats by Increasing M2 Microglia-Possible Involvement of the IL-4R/STAT6/PPARγ Pathway

延迟三天再通可通过增加 M2 小胶质细胞改善 pMCAO 大鼠的神经功能 - 可能涉及 IL-4R/STAT6/PPARγ 通路

期刊:Translational Stroke Research

影响因子:3.8

doi:10.1007/s12975-022-01032-5

Ruiqing Kang #, Marcin Gamdzyk #, Yujie Luo, Hong Tang, Lei Huang, Cameron Lenahan, Desislava Doycheva, Dujuan Li, Jiping Tang, Sheng Tan, John H Zhang

发表日期：2023

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BMS-470539 Attenuates Oxidative Stress and Neuronal Apoptosis via MC1R/cAMP/PKA/Nurr1 Signaling Pathway in a Neonatal Hypoxic-Ischemic Rat Model

BMS-470539 通过 MC1R/cAMP/PKA/Nurr1 信号通路减轻新生缺氧缺血大鼠模型中的氧化应激和神经元凋亡

期刊:Oxidative Medicine and Cellular Longevity

doi:10.1155/2022/4054938

Shufeng Yu, Desislava Met Doycheva, Marcin Gamdzyk, Yuanyuan Gao, Yong Guo, Zackary D Travis, Jiping Tang, Wen-Xiong Chen, John H Zhang

细胞生物学

GPCR/Calcium/cAMP

发表日期：2022

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Activation of MC1R with BMS-470539 attenuates neuroinflammation via cAMP/PKA/Nurr1 pathway after neonatal hypoxic-ischemic brain injury in rats

使用 BMS-470539 激活 MC1R 可减轻大鼠新生儿缺氧缺血性脑损伤后通过 cAMP/PKA/Nurr1 通路引起的神经炎症

期刊:Journal of Neuroinflammation

影响因子:9.3

doi:10.1186/s12974-021-02078-2

Shufeng Yu, Desislava Met Doycheva, Marcin Gamdzyk, Yijun Yang, Cameron Lenahan, Gaigai Li, Dujuan Li, Lifei Lian, Jiping Tang, Jun Lu, John H Zhang

GPCR/Calcium/cAMP

Immunology/Inflammation

发表日期：2021

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Inhibition of mast cell tryptase attenuates neuroinflammation via PAR-2/p38/NFκB pathway following asphyxial cardiac arrest in rats

抑制肥大细胞类胰蛋白酶可通过 PAR-2/p38/NFκB 通路减轻大鼠窒息心脏骤停后的神经炎症

期刊:Journal of Neuroinflammation

影响因子:9.3

doi:10.1186/s12974-020-01808-2

Umut Ocak, Pinar Eser Ocak, Lei Huang, Weilin Xu, Yuchun Zuo, Peng Li, Marcin Gamdzyk, Gang Zuo, Jun Mo, Guangyu Zhang, John H Zhang4

Immunology/Inflammation

发表日期：2020

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Inhibition of EZH2 (Enhancer of Zeste Homolog 2) Attenuates Neuroinflammation via H3k27me3/SOCS3/TRAF6/NF-κB (Trimethylation of Histone 3 Lysine 27/Suppressor of Cytokine Signaling 3/Tumor Necrosis Factor Receptor Family 6/Nuclear Factor-κB) in a Rat Model of Subarachnoid Hemorrhage

抑制 EZH2（Zeste 同源物 2 的增强子）可通过 H3k27me3/SOCS3/TRAF6/NF-κB（组蛋白 3 赖氨酸 27 的三甲基化/细胞因子信号传导抑制因子 3/肿瘤坏死因子受体家族 6/核因子-κB）减轻蛛网膜下腔出血大鼠模型中的神经炎症

影响因子:7.8

doi:10.1161/STROKEAHA.120.029951

Yujie Luo #, Yuanjian Fang #, Ruiqing Kang, Cameron Lenahan, Marcin Gamdzyk, Zeyu Zhang, Takeshi Okada, Jiping Tang, Sheng Chen, John H Zhang

Immunology/Inflammation

发表日期：2020

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Pituitary Adenylate Cyclase-Activating Polypeptide Attenuates Brain Edema by Protecting Blood-Brain Barrier and Glymphatic System After Subarachnoid Hemorrhage in Rats

垂体腺苷酸环化酶激活多肽通过保护大鼠蛛网膜下腔出血后的血脑屏障和淋巴系统减轻脑水肿

期刊:Neurotherapeutics

影响因子:5.6

doi:10.1007/s13311-020-00925-3

Yuanjian Fang #, Hui Shi #, Reng Ren, Lei Huang, Takeshi Okada, Cameron Lenahan, Marcin Gamdzyk, Zachary D Travis, Qin Lu, Lihui Tang, Yi Huang, Keren Zhou, Jiping Tang, Jianmin Zhang, John H Zhang

发表日期：2020

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cGAS/STING Pathway Activation Contributes to Delayed Neurodegeneration in Neonatal Hypoxia-Ischemia Rat Model: Possible Involvement of LINE-1

cGAS/STING 通路激活导致新生缺氧缺血大鼠模型中的神经退行性延迟：LINE-1 可能参与其中

期刊:Molecular Neurobiology

影响因子:4.6

doi:10.1007/s12035-020-01904-7

Marcin Gamdzyk, Desislava Met Doycheva, Camila Araujo, Umut Ocak, Yujie Luo, Jiping Tang, John H Zhang

发表日期：2020

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Overexpression of Mfsd2a attenuates blood brain barrier dysfunction via Cav-1/Keap-1/Nrf-2/HO-1 pathway in a rat model of surgical brain injury

在大鼠手术性脑损伤模型中，Mfsd2a 的过度表达可通过 Cav-1/Keap-1/Nrf-2/HO-1 通路减轻血脑屏障功能障碍

期刊:Experimental Neurology

影响因子:4.6

doi:10.1016/j.expneurol.2020.113203

Pinar Eser Ocak, Umut Ocak, Prativa Sherchan, Marcin Gamdzyk, Jiping Tang, John H Zhang

发表日期：2020

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Ghrelin attenuates oxidative stress and neuronal apoptosis via GHSR-1α/AMPK/Sirt1/PGC-1α/UCP2 pathway in a rat model of neonatal HIE

生长素释放肽通过 GHSR-1α/AMPK/Sirt1/PGC-1α/UCP2 通路减轻新生儿 HIE 大鼠模型中的氧化应激和神经元凋亡

期刊:Free Radical Biology and Medicine

影响因子:7.1

doi:10.1016/j.freeradbiomed.2019.07.001

Juan Huang, Wei Liu, Desislava Met Doycheva, Marcin Gamdzyk, Weitian Lu, Jiping Tang, John H Zhang

细胞生物学

发表日期：2019

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