日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Ghrelin Receptor Deletion or Pharmacological Inhibition Improves Muscle Function in Aging Male Mice.

生长素释放肽受体缺失或药物抑制可改善老年雄性小鼠的肌肉功能。

Kerr Haiming L, Krumm Kora, Myree Nornubari, Rybachok Artur, Dacek Elizabeth, Irwin Brynn, Jiang Siyi, Caeiro Lucas, Anderson Barbara, Li Theresa, Chen Amanda, Burnside Ross, Li Jessica, Sydor Morgan, Marcinek David J, Merrihew Gennifer E, MacDonald James W, Bammler Theo K, MacCoss Michael J, Garcia Jose M

On the Feasibility of Clinical Studies with Cross-Linking Mass Spectrometry

交联质谱法临床研究的可行性

Park, Sung-Gun; Ostrom, Ethan L; Liu, Sophia; Marcinek, David J; Bruce, James E

Striatal dopamine and skeletal muscle energy metabolism in older adults

老年人的纹状体多巴胺和骨骼肌能量代谢

Rosano, Caterina; Bohnen, Nico I; Lopresti, Brian; Chahine, Lana M; Barnes, Haley N; Studenski, Stephanie L; Glynn, Nancy W; Newman, Anne B; Marcinek, David J; Hepple, Russell T; Coen, Paul M

Inducible and reversible SOD2 knockdown in mouse skeletal muscle drives impaired pyruvate oxidation and reduced metabolic flexibility.

小鼠骨骼肌中可诱导和可逆的 SOD2 敲低导致丙酮酸氧化受损和代谢灵活性降低

Ostrom Ethan L, Stuppard Rudy, Mattson-Hughes Aurora, Marcinek David J

Contemporary insights into elamipretide's mitochondrial mechanism of action and therapeutic effects

对依拉米普瑞肽线粒体作用机制和治疗效果的最新认识

Sabbah, Hani N; Alder, Nathan N; Sparagna, Genevieve C; Bruce, James E; Stauffer, Brian L; Chao, Luke H; Pitceathly, Robert D S; Maack, Christoph; Marcinek, David J

A Pilot Trial of Nicotinamide Riboside and Coenzyme Q10 on Inflammation and Oxidative Stress in CKD

烟酰胺核苷和辅酶Q10对慢性肾脏病炎症和氧化应激的初步研究

Ahmadi, Armin; Valencia, Ana P; Begue, Gwénaëlle; Norman, Jennifer E; Fan, Sili; Durbin-Johnson, Blythe P; Jenner, Bradley N; Campbell, Matthew D; Reyes, Gustavo; Kapahi, Pankaj; Himmelfarb, Jonathan; de Boer, Ian H; Marcinek, David J; Kestenbaum, Bryan R; Gamboa, Jorge L; Roshanravan, Baback

The Mitochondria-Targeted Peptide Therapeutic Elamipretide Improves Cardiac and Skeletal Muscle Function During Aging Without Detectable Changes in Tissue Epigenetic or Transcriptomic Age

靶向线粒体的肽类治疗药物Elamipretide可在不引起组织表观遗传或转录组年龄可检测变化的情况下,改善衰老过程中的心肌和骨骼肌功能。

Mitchell, Wayne; Pharaoh, Gavin; Tyshkovskiy, Alexander; Campbell, Matthew; Marcinek, David J; Gladyshev, Vadim N

Reduced oxidative capacity of skeletal muscle mitochondria IS a fundamental consequence of adult ageing

骨骼肌线粒体氧化能力下降是成年衰老的一个根本后果。

Marcinek, David J; Ferrucci, Luigi

Age-related changes of skeletal muscle metabolic response to contraction are also sex-dependent

骨骼肌对收缩的代谢反应随年龄的变化也存在性别差异。

Campbell, Matthew D; Djukovic, Danijel; Raftery, Daniel; Marcinek, David J

Mitochondrial Dysfunction Drives Age-Related Degeneration of the Thoracic Aorta

线粒体功能障碍驱动胸主动脉的年龄相关性退行性变

Dhanekula, Arjune S; Harrison, Benjamin R; Pharaoh, Gavin; Mattson-Hughes, Aurora; Tarantini, Stefano; Stuppard, Rudolph; DeRoo, Scott C; Burke, Christopher R; Hwang, Billiana; Pal, Jay D; Mulligan, Michael S; Marcinek, David J