Loss of the endocytic tumor suppressor HD-PTP phenocopies LKB1 and promotes RAS-driven oncogenesis
内吞肿瘤抑制因子HD-PTP的缺失会模拟LKB1的表型,并促进RAS驱动的肿瘤发生。
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doi:10.1101/2023.01.26.525772
Seong, Chang-Soo; Huang, Chunzi; Boese, Austin C; Hou, Yuning; Koo, Junghui; Mouw, Janna K; Rupji, Manali; Joseph, Greg; Johnston, H Richard; Claussen, Henry; Switchenko, Jeffrey M; Behera, Madhusmita; Churchman, Michelle; Kolesar, Jill M; Arnold, Susanne M; Kerrigan, Katie; Akerley, Wallace; Colman, Howard; Johns, Margaret A; Arciero, Cletus; Zhou, Wei; Marcus, Adam I; Ramalingam, Suresh S; Fu, Haian; Gilbert-Ross, Melissa