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Human responses to the DNA prime/chimpanzee adenovirus (ChAd63) boost vaccine identify CSP, AMA1 and TRAP MHC Class I-restricted epitopes

人体对DNA启动/黑猩猩腺病毒（ChAd63）加强疫苗的反应可识别CSP、AMA1和TRAP MHC I类限制性表位

doi:10.1371/journal.pone.0318098

Ganeshan, Harini; Huang, Jun; Belmonte, Maria; Belmonte, Arnel; Inoue, Sandra; Velasco, Rachel; Maiolatesi, Santina; Limbach, Keith; Patterson, Noelle; Sklar, Marvin J; Soisson, Lorraine; Epstein, Judith E; Edgel, Kimberly A; Peters, Bjoern; Hollingdale, Michael R; Villasante, Eileen; Duplessis, Christopher A; Sedegah, Martha

A randomized clinical trial of the impact of melatonin on influenza vaccine: Outcomes from the melatonin and vaccine response immunity and chronobiology study (MAVRICS)

褪黑素对流感疫苗影响的随机临床试验：褪黑素与疫苗反应免疫和时间生物学研究 (MAVRICS) 的结果

期刊:Human Vaccines & Immunotherapeutics

影响因子:3.5

doi:10.1080/21645515.2024.2419742

Lee, Rachel U; Watson, Nora L; Glickman, Gena L; White, Lindsey; Isidean, Sandra D; Porter, Chad K; Hollis-Perry, Monique; Walther, Samuel R; Maiolatesi, Santina; Sedegah, Martha; Ganeshan, Harini; Huang, Jun; Boulifard, David A; Ewing, Daniel; Sundaram, Appavu K; Harrison, Elizabeth M; DeTizio, Katherine; Belmonte, Maria; Belmonte, Arnel; Inoue, Sandra; Easterling, Alexandra; Cooper, Elizabeth S; Danko, Janine

Plasma microrna expression profile for reduced ejection fraction in dilated cardiomyopathy

扩张型心肌病射血分数降低的血浆微小RNA表达谱

期刊:Scientific Reports

影响因子:3.9

doi:10.1038/s41598-021-87086-1

Calderon-Dominguez, Maria; Belmonte, Thalía; Quezada-Feijoo, Maribel; Ramos, Mónica; Calderon-Dominguez, Juan; Campuzano, Oscar; Mangas, Alipio; Toro, Rocio

Comparison of the impact of allelic polymorphisms in PfAMA1 on the induction of T Cell responses in high and low malaria endemic communities in Ghana

比较 PfAMA1 等位基因多态性对加纳高疟疾流行区和低疟疾流行区诱导 T 细胞反应的影响

期刊:Malaria Journal

影响因子:2.4

doi:10.1186/s12936-021-03900-1

Ebenezer A Ofori, John K A Tetteh, Augustina Frimpong, Harini Ganeshan, Maria Belmonte, Bjoern Peters, Eileen Villasante, Martha Sedegah, Michael F Ofori, Kwadwo A Kusi

Identification of Plasmodium falciparum circumsporozoite protein-specific CD8+ T cell epitopes in a malaria exposed population

在疟疾暴露人群中鉴定恶性疟原虫环子孢子蛋白特异性 CD8+ T 细胞表位

期刊:PLoS One

影响因子:2.9

doi:10.1371/journal.pone.0228177

Kwadwo A Kusi, Felix E Aggor, Linda E Amoah, Dorothy Anum, Yvonne Nartey, Daniel Amoako-Sakyi, Dorcas Obiri-Yeboah, Michael Hollingdale, Harini Ganeshan, Maria Belmonte, Bjoern Peters, Yohan Kim, John Tetteh, Eric Kyei-Baafour, Daniel Dodoo, Eileen Villasante, Martha Sedegah

DNA prime/Adenovirus boost malaria vaccine encoding P. falciparum CSP and AMA1 induces sterile protection associated with cell-mediated immunity

编码恶性疟原虫 CSP 和 AMA1 的 DNA 引发/腺病毒加强疟疾疫苗可诱导与细胞介导免疫相关的无菌保护

期刊:PLoS One

影响因子:2.9

doi:10.1371/journal.pone.0055571

Ilin Chuang, Martha Sedegah, Susan Cicatelli, Michele Spring, Mark Polhemus, Cindy Tamminga, Noelle Patterson, Melanie Guerrero, Jason W Bennett, Shannon McGrath, Harini Ganeshan, Maria Belmonte, Fouzia Farooq, Esteban Abot, Jo Glenna Banania, Jun Huang, Rhonda Newcomer, Lisa Rein, Dianne Litilit, N

Identification of minimal human MHC-restricted CD8+ T-cell epitopes within the Plasmodium falciparum circumsporozoite protein (CSP)

鉴定恶性疟原虫环子孢子蛋白 (CSP) 内的最小人类 MHC 限制性 CD8+ T 细胞表位

期刊:Malaria Journal

影响因子:2.4

doi:10.1186/1475-2875-12-185

Martha Sedegah, Yohan Kim, Harini Ganeshan, Jun Huang, Maria Belmonte, Esteban Abot, Jo Glenna Banania, Fouzia Farooq, Shannon McGrath, Bjoern Peters, Alessandro Sette, Lorraine Soisson, Carter Diggs, Denise L Doolan, Cindy Tamminga, Eileen Villasante, Michael R Hollingdale, Thomas L Richie

Ex vivo tetramer staining and cell surface phenotyping for early activation markers CD38 and HLA-DR to enumerate and characterize malaria antigen-specific CD8+ T-cells induced in human volunteers immunized with a Plasmodium falciparum adenovirus-vectored malaria vaccine expressing AMA1

对早期活化标记物 CD38 和 HLA-DR 进行体外四聚体染色和细胞表面表型分析，以计数和表征在用表达 AMA1 的恶性疟原虫腺病毒载体疟疾疫苗免疫的人类志愿者中诱导的疟疾抗原特异性 CD8+ T 细胞

期刊:Malaria Journal

影响因子:2.4

doi:10.1186/1475-2875-12-376

Robert Schwenk, Glenna Banania, Judy Epstein, Yohan Kim, Bjoern Peters, Maria Belmonte, Harini Ganeshan, Jun Huang, Sharina Reyes, Anette Stryhn, Christian F Ockenhouse, Soren Buus, Thomas L Richie, Martha Sedegah

Adenovirus 5-vectored P. falciparum vaccine expressing CSP and AMA1. Part A: safety and immunogenicity in seronegative adults

表达 CSP 和 AMA1 的腺病毒 5 载体恶性疟原虫疫苗。A 部分：血清阴性成人的安全性和免疫原性

期刊:PLoS One

影响因子:2.9

doi:10.1371/journal.pone.0024586

Martha Sedegah, Cindy Tamminga, Shannon McGrath, Brent House, Harini Ganeshan, Jennylynn Lejano, Esteban Abot, Glenna J Banania, Renato Sayo, Fouzia Farooq, Maria Belmonte, Nalini Manohar, Nancy O Richie, Chloe Wood, Carole A Long, David Regis, Francis T Williams, Meng Shi, Ilin Chuang, Michele Spri

免疫

发表日期：2011

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Highly dynamic mechanical transitions in embryonic cell populations during Drosophila gastrulation.

果蝇原肠胚形成过程中胚胎细胞群的高度动态力学转变

Human responses to the DNA prime/chimpanzee adenovirus (ChAd63) boost vaccine identify CSP, AMA1 and TRAP MHC Class I-restricted epitopes

人体对DNA启动/黑猩猩腺病毒（ChAd63）加强疫苗的反应可识别CSP、AMA1和TRAP MHC I类限制性表位

A randomized clinical trial of the impact of melatonin on influenza vaccine: Outcomes from the melatonin and vaccine response immunity and chronobiology study (MAVRICS)

褪黑素对流感疫苗影响的随机临床试验：褪黑素与疫苗反应免疫和时间生物学研究 (MAVRICS) 的结果

Plasma microrna expression profile for reduced ejection fraction in dilated cardiomyopathy

扩张型心肌病射血分数降低的血浆微小RNA表达谱

Comparison of the impact of allelic polymorphisms in PfAMA1 on the induction of T Cell responses in high and low malaria endemic communities in Ghana

比较 PfAMA1 等位基因多态性对加纳高疟疾流行区和低疟疾流行区诱导 T 细胞反应的影响

Identification of Plasmodium falciparum circumsporozoite protein-specific CD8+ T cell epitopes in a malaria exposed population

在疟疾暴露人群中鉴定恶性疟原虫环子孢子蛋白特异性 CD8+ T 细胞表位

DNA prime/Adenovirus boost malaria vaccine encoding P. falciparum CSP and AMA1 induces sterile protection associated with cell-mediated immunity

编码恶性疟原虫 CSP 和 AMA1 的 DNA 引发/腺病毒加强疟疾疫苗可诱导与细胞介导免疫相关的无菌保护

Identification of minimal human MHC-restricted CD8+ T-cell epitopes within the Plasmodium falciparum circumsporozoite protein (CSP)

鉴定恶性疟原虫环子孢子蛋白 (CSP) 内的最小人类 MHC 限制性 CD8+ T 细胞表位

Ex vivo tetramer staining and cell surface phenotyping for early activation markers CD38 and HLA-DR to enumerate and characterize malaria antigen-specific CD8+ T-cells induced in human volunteers immunized with a Plasmodium falciparum adenovirus-vectored malaria vaccine expressing AMA1

对早期活化标记物 CD38 和 HLA-DR 进行体外四聚体染色和细胞表面表型分析，以计数和表征在用表达 AMA1 的恶性疟原虫腺病毒载体疟疾疫苗免疫的人类志愿者中诱导的疟疾抗原特异性 CD8+ T 细胞

Adenovirus 5-vectored P. falciparum vaccine expressing CSP and AMA1. Part A: safety and immunogenicity in seronegative adults

表达 CSP 和 AMA1 的腺病毒 5 载体恶性疟原虫疫苗。A 部分：血清阴性成人的安全性和免疫原性