日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Adipose tissue from oesophageal adenocarcinoma patients is differentially affected by chemotherapy and chemoradiotherapy regimens altering immune cell phenotype and cancer cell metabolism

食管腺癌患者的脂肪组织受化疗和放化疗方案的影响程度不同,这些方案会改变免疫细胞表型和癌细胞代谢。

Fiona O'Connell ,Eimear Mylod ,Noel E Donlon ,Maria Davern ,Christine Butler ,Niamh O'Connor ,Meghana S Menon ,Claire L Donohoe ,Narayanasamy Ravi ,Derek G Doherty ,Margaret R Dunne ,John V Reynolds ,Helen M Roche ,Jacintha O'Sullivan

Real-time ex vivo monitoring of NK cell migration toward obesity-associated oesophageal adenocarcinoma following modulation of CX3CR1

实时体外监测 CX3CR1 调节后 NK 细胞向肥胖相关食管腺癌的迁移

Eimear Mylod, Fiona O'Connell, Noel E Donlon, Maria Davern, Caroline Marion, Christine Butler, John V Reynolds, Joanne Lysaght, Melissa J Conroy

Acidosis significantly alters immune checkpoint expression profiles of T cells from oesophageal adenocarcinoma patients

酸中毒显著改变食管腺癌患者 T 细胞的免疫检查点表达谱

Maria Davern #, Noel E Donlon #, Fiona O'Connell, Caoimhe Gaughan, Cillian O'Donovan, Mohammed Habash, Andrew D Sheppard, Michael MacLean, Margaret R Dunne, Jenny Moore, Hugo Temperley, Melissa J Conroy, Christine Butler, Anshul Bhardwaj, Narayanasamy Ravi, Claire L Donohoe, John V Reynolds, Joanne

FLOT and CROSS chemotherapy regimens alter the frequency of CD27+ and CD69+ T cells in oesophagogastric adenocarcinomas: implications for combination with immunotherapy

FLOT 和 CROSS 化疗方案改变食管胃腺癌中 CD27+ 和 CD69+ T 细胞的频率:与免疫疗法联合治疗的意义

Maria Davern, Noel E Donlon, Andrew S Sheppard, Klaudia D Majcher, Fiona O' Connell, Aisling B Heeran, Malika Grant, Robert A Farrell, Conall Hayes, Dara Bracken-Clarke, Melissa J Conroy, Emma Foley, Dermot O' Toole, Anshul Bhardwaj, Narayanasamy Ravi, John V Reynolds, Stephen G Maher, Jacintha O' S

Cooperation between chemotherapy and immune checkpoint blockade to enhance anti-tumour T cell immunity in oesophageal adenocarcinoma

化疗与免疫检查点阻断协同增强食管腺癌抗肿瘤 T 细胞免疫

Maria Davern, Noel E Donlon, Fiona O' Connell, Andrew D Sheppard, Conall Hayes, Ross King, Hugo Temperley, Christine Butler, Anshul Bhardwaj, Jenny Moore, Dara Bracken-Clarke, Claire Donohoe, Narayanasamy Ravi, John V Reynolds, Stephen G Maher, Melissa J Conroy, Joanne Lysaght

PD-1 and TIGIT blockade differentially affect tumour cell survival under hypoxia and glucose deprived conditions in oesophageal adenocarcinoma; implications for overcoming resistance to PD-1 blockade in hypoxic tumours

PD-1 和 TIGIT 阻断对食管腺癌在缺氧和缺糖条件下肿瘤细胞存活率有不同的影响;对克服缺氧肿瘤对 PD-1 阻断的耐药性具有重要意义

Maria Davern, Marie-Claire Fitzgerald, Croí E Buckley, Aisling B Heeran, Noel E Donlon, Jason McGrath, Fiona O' Connell, Malvika R Deshpande, Conall Hayes, Jamie MacDonald, Andrew D Sheppard, John V Reynolds, Stephen G Maher, Niamh Lynam-Lennon, Brona Murphy, Joanne Lysaght

PD-1 blockade enhances chemotherapy toxicity in oesophageal adenocarcinoma

PD-1 阻断增强食管腺癌化疗毒性

Maria Davern, Rebecca M O' Brien #, Jason McGrath #, Noel E Donlon #, Ashanty M Melo, Croí E Buckley, Andrew D Sheppard, John V Reynolds, Niamh Lynam-Lennon, Stephen G Maher, Joanne Lysaght