NF2 Loss Promotes Oncogenic RAS-Induced Thyroid Cancers via YAP-Dependent Transactivation of RAS Proteins and Sensitizes Them to MEK Inhibition
NF2 缺失通过 YAP 依赖的 RAS 蛋白转录激活促进致癌 RAS 诱发的甲状腺癌，并使其对 MEK 抑制敏感
期刊:Cancer Discovery
影响因子:29.7
doi:10.1158/2159-8290.CD-15-0330
Maria E R Garcia-Rendueles, Julio C Ricarte-Filho, Brian R Untch, Iňigo Landa, Jeffrey A Knauf, Francesca Voza, Vicki E Smith, Ian Ganly, Barry S Taylor, Yogindra Persaud, Gisele Oler, Yuqiang Fang, Suresh C Jhanwar, Agnes Viale, Adriana Heguy, Kety H Huberman, Filippo Giancotti, Ronald Ghossein, Ja
