Maria G Demos相关文献与解析，生知库 | 链接生命科学的每一步

日期影响因子

The HCK/BTK inhibitor KIN-8194 is active in MYD88-driven lymphomas and overcomes mutated BTKCys481 ibrutinib resistance

HCK/BTK 抑制剂 KIN-8194 对 MYD88 驱动的淋巴瘤有效，并可克服突变的 BTKCys481 依鲁替尼耐药性

影响因子:21

doi:10.1182/blood.2021011405

Guang Yang, Jinhua Wang, Li Tan, Manit Munshi, Xia Liu, Amanda Kofides, Jiaji G Chen, Nicholas Tsakmaklis, Maria G Demos, Maria Luisa Guerrera, Lian Xu, Zachary R Hunter, Jinwei Che, Christopher J Patterson, Kirsten Meid, Jorge J Castillo, Nikhil C Munshi, Kenneth C Anderson, Michael Cameron, Sara J

发表日期：2021

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SYK is activated by mutated MYD88 and drives pro-survival signaling in MYD88 driven B-cell lymphomas

SYK 由突变的 MYD88 激活，并在 MYD88 驱动的 B 细胞淋巴瘤中驱动促生存信号传导

期刊:Blood Cancer Journal

影响因子:12.9

doi:10.1038/s41408-020-0277-6

Manit Munshi, Xia Liu, Jiaji G Chen, Lian Xu, Nickolas Tsakmaklis, Maria G Demos, Amanda Kofides, Maria Luisa Guerrera, Cristina Jimenez, Gloria G Chan, Zachary R Hunter, M Lia Palomba, Kimon V Argyropoulos, Kirsten Meid, Andrew Keezer, Joshua Gustine, Toni Dubeau, Jorge J Castillo, Christopher J Pa

发表日期：2020

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Expression of the prosurvival kinase HCK requires PAX5 and mutated MYD88 signaling in MYD88-driven B-cell lymphomas

在 MYD88 驱动的 B 细胞淋巴瘤中，促生存激酶 HCK 的表达需要 PAX5 和突变的 MYD88 信号传导

期刊:Blood Advances

影响因子:7.4

doi:10.1182/bloodadvances.2019000947

Xia Liu, Jiaji G Chen, Manit Munshi, Zachary R Hunter, Lian Xu, Amanda Kofides, Nickolas Tsakmaklis, Maria G Demos, Maria Luisa Guerrera, Gloria G Chan, Cristina Jimenez, Christopher J Patterson, Kirsten Meid, Andrew Keezer, Jorge J Castillo, Steven P Treon, Guang Yang

发表日期：2020

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BTKCys481Ser drives ibrutinib resistance via ERK1/2 and protects BTKwild-type MYD88-mutated cells by a paracrine mechanism

BTKCys481Ser 通过 ERK1/2 驱动伊布替尼耐药性，并通过旁分泌机制保护 BTKwild 型 MYD88 突变细胞

影响因子:21

doi:10.1182/blood-2017-10-811752

Jiaji G Chen, Xia Liu, Manit Munshi, Lian Xu, Nicholas Tsakmaklis, Maria G Demos, Amanda Kofides, Maria Luisa Guerrera, Gloria G Chan, Christopher J Patterson, Kirsten Meid, Joshua Gustine, Toni Dubeau, Patricia Severns, Jorge J Castillo, Zachary R Hunter, Jinhua Wang, Sara J Buhrlage, Nathanael S G

发表日期：2018

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