日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Activation of the mTORC1/PGC-1 axis promotes mitochondrial biogenesis and induces cellular senescence in the lung epithelium

mTORC1/PGC-1 轴的激活促进线粒体的生物合成并诱导肺上皮细胞衰老

Ross Summer, Hoora Shaghaghi, DeLeila Schriner, Willy Roque, Dominic Sales, Karina Cuevas-Mora, Vilas Desai, Alok Bhushan, Maria I Ramirez, Freddy Romero

NKX2-1-AS1 negatively regulates CD274/PD-L1, cell-cell interaction genes, and limits human lung carcinoma cell migration

NKX2-1-AS1 负向调控 CD274/PD-L1、细胞间相互作用基因并限制人类肺癌细胞迁移

Hasmeena Kathuria, Guetchyn Millien, Liam McNally, Adam C Gower, Jean-Bosco Tagne, Yuxia Cao, Maria I Ramirez

PKA and CDK5 can phosphorylate specific serines on the intracellular domain of podoplanin (PDPN) to inhibit cell motility

PKA 和 CDK5 可以磷酸化细胞内结构域 (PDPN) 上的特定丝氨酸,从而抑制细胞运动

Harini Krishnan, Edward P Retzbach, Maria I Ramirez, Tong Liu, Hong Li, W Todd Miller, Gary S Goldberg

Grainyhead-like 2 (GRHL2) distribution reveals novel pathophysiological differences between human idiopathic pulmonary fibrosis and mouse models of pulmonary fibrosis

Grainyhead-like 2 (GRHL2) 分布揭示了人类特发性肺纤维化与小鼠肺纤维化模型之间的新病理生理差异

Saaket Varma, Poornima Mahavadi, Satish Sasikumar, Leah Cushing, Tessa Hyland, Ann E Rosser, Daniela Riccardi, Jining Lu, Tanya V Kalin, Vladimir V Kalinichenko, Andreas Guenther, Maria I Ramirez, Annie Pardo, Moisés Selman, David Warburton

Serines in the intracellular tail of podoplanin (PDPN) regulate cell motility

细胞内平足蛋白尾部(PDPN)的丝氨酸调节细胞运动

Harini Krishnan, Jhon A Ochoa-Alvarez, Yongquan Shen, Evan Nevel, Meenakshi Lakshminarayanan, Mary C Williams, Maria I Ramirez, W Todd Miller, Gary S Goldberg

The transcription factors Grainyhead-like 2 and NK2-homeobox 1 form a regulatory loop that coordinates lung epithelial cell morphogenesis and differentiation

转录因子 Grainyhead-like 2 和 NK2-homeobox 1 形成调节环,协调肺上皮细胞的形态发生和分化

Saaket Varma, Yuxia Cao, Jean-Bosco Tagne, Meenakshi Lakshminarayanan, Jun Li, Thomas B Friedman, Robert J Morell, David Warburton, Darrell N Kotton, Maria I Ramirez

Type I alveolar epithelial cells mount innate immune responses during pneumococcal pneumonia

型肺泡上皮细胞在肺炎球菌性肺炎期间产生先天免疫反应

Kazuko Yamamoto, Joseph D Ferrari, Yuxia Cao, Maria I Ramirez, Matthew R Jones, Lee J Quinton, Joseph P Mizgerd

Genome-wide analyses of Nkx2-1 binding to transcriptional target genes uncover novel regulatory patterns conserved in lung development and tumors

Nkx2-1 与转录靶基因结合的全基因组分析揭示了肺发育和肿瘤中保守的新型调控模式

Jean-Bosco Tagne, Sumeet Gupta, Adam C Gower, Steven S Shen, Saaket Varma, Meenakshi Lakshminarayanan, Yuxia Cao, Avrum Spira, Thomas L Volkert, Maria I Ramirez

Epigenetic mechanisms modulate thyroid transcription factor 1-mediated transcription of the surfactant protein B gene

表观遗传机制调节甲状腺转录因子 1 介导的表面活性蛋白 B 基因转录

Yuxia Cao, Tiffany Vo, Guetchyn Millien, Jean-Bosco Tagne, Darrell Kotton, Robert J Mason, Mary C Williams, Maria I Ramirez

Increased PEA3/E1AF and decreased Net/Elk-3, both ETS proteins, characterize human NSCLC progression and regulate caveolin-1 transcription in Calu-1 and NCI-H23 NSCLC cell lines

两种 ETS 蛋白 PEA3/E1AF 增加和 Net/Elk-3 减少是人类 NSCLC 进展的特征,并调节 Calu-1 和 NCI-H23 NSCLC 细胞系中的 caveolin-1 转录

Karin A Sloan, Hector A Marquez, Jun Li, Yuxia Cao, Anne Hinds, Carl J O'Hara, Satinder Kathuria, Maria I Ramirez, Mary C Williams, Hasmeena Kathuria