日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

HIV-1 Reverse Transcriptase Expression in HPV16-Infected Epidermoid Carcinoma Cells Alters E6 Expression and Cellular Metabolism, and Induces a Hybrid Epithelial/Mesenchymal Cell Phenotype

HPV16 感染的表皮样癌细胞中的 HIV-1 逆转录酶表达改变了 E6 表达和细胞代谢,并诱导了混合上皮/间充质细胞表型

Alla Zhitkevich, Ekaterina Bayurova, Darya Avdoshina, Natalia Zakirova, Galina Frolova, Sona Chowdhury, Alexander Ivanov, Ilya Gordeychuk, Joel M Palefsky, Maria Isaguliants

HIV-1 Protease as DNA Immunogen against Drug Resistance in HIV-1 Infection: DNA Immunization with Drug Resistant HIV-1 Protease Protects Mice from Challenge with Protease-Expressing Cells

HIV-1 蛋白酶作为 DNA 免疫原对抗 HIV-1 感染中的耐药性:用耐药 HIV-1 蛋白酶进行 DNA 免疫可保护小鼠免受蛋白酶表达细胞的攻击

Stefan Petkov, Athina Kilpeläinen, Ekaterina Bayurova, Anastasia Latanova, Dzeina Mezale, Ilse Fridrihsone, Elizaveta Starodubova, Juris Jansons, Alesja Dudorova, Ilya Gordeychuk, Britta Wahren, Maria Isaguliants

Reciprocal Inhibition of Immunogenic Performance in Mice of Two Potent DNA Immunogens Targeting HCV-Related Liver Cancer

两种针对 HCV 相关肝癌的强效 DNA 免疫原在小鼠体内相互抑制免疫原性

Juris Jansons, Dace Skrastina, Alisa Kurlanda, Stefan Petkov, Darya Avdoshina, Yulia Kuzmenko, Olga Krotova, Olga Trofimova, Ilya Gordeychuk, Irina Sominskaya, Maria Isaguliants

Alphavirus-Driven Interferon Gamma (IFNg) Expression Inhibits Tumor Growth in Orthotopic 4T1 Breast Cancer Model

α病毒驱动的干扰素γ(IFNg)表达抑制原位4T1乳腺癌模型中的肿瘤生长

Olga Trofimova, Ksenija Korotkaja, Dace Skrastina, Juris Jansons, Karina Spunde, Maria Isaguliants, Anna Zajakina

Replenishment of Hepatitis B Virus cccDNA Pool Is Restricted by Baseline Expression of Host Restriction Factors In Vitro

乙肝病毒 cccDNA 库的补充受到体外宿主限制因子基线表达的限制

Sergey Brezgin, Anastasiia Kostyusheva, Ekaterina Bayurova, Ilya Gordeychuk, Maria Isaguliants, Irina Goptar, Anastasiia Nikiforova, Valery Smirnov, Elena Volchkova, Dieter Glebe, Dmitry Kostyushev, Vladimir Chulanov

ATM and ATR Expression Potentiates HBV Replication and Contributes to Reactivation of HBV Infection upon DNA Damage

ATM 和 ATR 表达增强 HBV 复制并导致 DNA 损伤后 HBV 感染重新激活

Anastasiya Kostyusheva, Sergey Brezgin, Ekaterina Bayurova, Ilya Gordeychuk, Maria Isaguliants, Irina Goptar, Felix Urusov, Anastasiya Nikiforova, Elena Volchkova, Dmitry Kostyushev, Vladimir Chulanov

DNA immunization site determines the level of gene expression and the magnitude, but not the type of the induced immune response

DNA 免疫位点决定基因表达的水平和大小,但不决定诱导的免疫反应的类型

Stefan Petkov, Elizaveta Starodubova, Anastasia Latanova, Athina Kilpeläinen, Oleg Latyshev, Simons Svirskis, Britta Wahren, Francesca Chiodi, Ilya Gordeychuk, Maria Isaguliants

Fusion to Flaviviral Leader Peptide Targets HIV-1 Reverse Transcriptase for Secretion and Reduces Its Enzymatic Activity and Ability to Induce Oxidative Stress but Has No Major Effects on Its Immunogenic Performance in DNA-Immunized Mice

与黄病毒前导肽融合可靶向 HIV-1 逆转录酶进行分泌,并降低其酶活性和诱导氧化应激的能力,但对其在 DNA 免疫小鼠中的免疫原性性能没有重大影响

Anastasia Latanova, Stefan Petkov, Yulia Kuzmenko, Athina Kilpeläinen, Alexander Ivanov, Olga Smirnova, Olga Krotova, Sergey Korolev, Jorma Hinkula, Vadim Karpov, Maria Isaguliants, Elizaveta Starodubova

Comparative Immunogenicity in Rabbits of the Polypeptides Encoded by the 5' Terminus of Hepatitis C Virus RNA

丙型肝炎病毒RNA5'末端多肽在家兔体内的比较免疫原性

Irina Sominskaya, Juris Jansons, Anastasija Dovbenko, Natalia Petrakova, Ilva Lieknina, Marija Mihailova, Oleg Latyshev, Olesja Eliseeva, Irina Stahovska, Inara Akopjana, Ivars Petrovskis, Maria Isaguliants

Oxidative stress induced by HIV-1 reverse transcriptase modulates the enzyme's performance in gene immunization

HIV-1 逆转录酶诱导的氧化应激调节该酶在基因免疫中的表现

Maria Isaguliants, Olga Smirnova, Alexander V Ivanov, Athina Kilpelainen, Yulia Kuzmenko, Stefan Petkov, Anastasia Latanova, Olga Krotova, Gunnel Engström, Vadim Karpov, Sergey Kochetkov, Britta Wahren, Elizaveta Starodubova