日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Synthesis, biological, and biophysical studies of DAG-indololactones designed as selective activators of RasGRP

作为 RasGRP 选择性激活剂的 DAG-吲哚内酯的合成、生物学和生物物理研究

Lia C Garcia, Lucia Gandolfi Donadío, Ella Mann, Sofiya Kolusheva, Noemi Kedei, Nancy E Lewin, Colin S Hill, Jessica S Kelsey, Jing Yang, Timothy E Esch, Marina Santos, Megan L Peach, James A Kelley, Peter M Blumberg, Raz Jelinek, Victor E Marquez, Maria J Comin

Preclinical development of novel Rac1-GEF signaling inhibitors using a rational design approach in highly aggressive breast cancer cell lines

采用合理设计方法在高度侵袭性乳腺癌细胞系中进行新型 Rac1-GEF 信号抑制剂的临床前开发

Georgina A Cardama, Maria J Comin, Leandro Hornos, Nazareno Gonzalez, Lucas Defelipe, Adrian G Turjanski, Daniel F Alonso, Daniel E Gomez, Pablo Lorenzano Menna