Improved Protocol for Reproducible Human Cortical Organoids Reveals Early Alterations in Metabolism with MAPT Mutations
改进的可重复人类皮层类器官培养方案揭示了MAPT突变引起的早期代谢改变
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doi:10.1101/2023.07.11.548571
Bertucci, Taylor; Bowles, Kathryn R; Lotz, Steven; Qi, Le; Stevens, Katherine; Goderie, Susan K; Borden, Susan; Oja, Laura Maria; Lane, Keith; Lotz, Ryan; Lotz, Hailey; Chowdhury, Rebecca; Joy, Shona; Arduini, Brigitte L; Butler, David C; Miller, Michael; Baron, Heide; Sandhof, Carl Alexander; Silva, M Catarina; Haggarty, Stephen J; Karch, Celeste M; Geschwind, Daniel H; Goate, Alison M; Temple, Sally