Inhibition of IRAK4 by microbial trimethylamine blunts metabolic inflammation and ameliorates glycemic control.
微生物三甲胺对 IRAK4 的抑制作用可减轻代谢炎症并改善血糖控制。
期刊:Nature Metabolism
影响因子:20.8
doi:10.1038/s42255-025-01413-8
Chilloux Julien, Brial Francois, Everard Amandine, Smyth David, Andrikopoulos Petros, Zhang Liyong, Plovier Hubert, Myridakis Antonis, Hoyles Lesley, Moreno-Navarrete José Maria, Luque Jèssica Latorre, Casagrande Viviana, Menghini Rossella, Ahmetaj-Shala Blerina, Blancher Christine, Martinez-Gili Laura, Gencer Selin, Fearnside Jane F, Barton Richard H, Neves Ana Luisa, Rothwell Alice R, Gérard Christelle, Calderari Sophie, Williamson Mark J, Fuchs Julian E, Govada Lata, Boulangé Claire L, Patel Saroor, Scott James, Thursz Mark, Chayen Naomi, Glen Robert C, Gooderham Nigel J, Nicholson Jeremy K, Federici Massimo, Fernández-Real José Manuel, Gauguier Dominique, Liu Peter P, Cani Patrice D, Dumas Marc-Emmanuel
微生物学
IRAK4
Immunology/Inflammation
炎症
