日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Activation of PPARγ redirects fibro-adipogenic progenitors to replace ectopic bone with fat in models of fibrodysplasia ossificans progressiva and trauma-induced heterotopic ossification

在进行性骨化性纤维发育不良和创伤诱导的异位骨化模型中,PPARγ的激活可引导纤维脂肪生成祖细胞将异位骨替换为脂肪。

Koirala, Pratik; Chen, Ziyu; Hanumantharao, Samerender Nagam; Siegel, Ashley E; Liu, Chang; Williams, Zachary; Sekhon, Harshaan; Maridas, David; Mishina, Yuji; Rosen, Vicki; Agarwal, Shailesh

A closed-loop cell therapy engineered to autonomously secrete Activin A inhibitor protects from fibrodysplasia ossificans progressiva.

一种经过基因工程改造,能够自主分泌 Activin A 抑制剂的闭环细胞疗法可以预防进行性骨化性纤维发育不良。

Koirala Pratik, Chen Ziyu, Wu Mengfan, Maridas David, Siegel Ashley, Liu Chang, Hanumantharao Samerender, Mishina Yuji, Rosen Vicki, Agarwal Shailesh

Acute regulation of murine adipose tissue lipolysis and insulin resistance by the TGFβ superfamily protein GDF3.

TGFβ超家族蛋白GDF3对小鼠脂肪组织脂肪分解和胰岛素抵抗的急性调节

Kotikalapudi Nagasuryaprasad, Ramachandran Deepti, Vieira Daniel, Rubio William B, Gipson Gregory R, Troncone Luca, Vestal Kylie, Maridas David E, Rosen Vicki, Yu Paul B, Thompson Thomas B, Banks Alexander S

Complex Regulatory Interactions at GDF5 Shape Joint Morphology and Osteoarthritis Disease Risk

GDF5 的复杂调控相互作用影响关节形态和骨关节炎疾病风险

Clarissa R Coveney ,David Maridas ,Hao Chen ,Pushpanathan Muthuirulan ,Zun Liu ,Evelyn Jagoda ,Siddharth Yarlagadda ,Mohammadreza Movahhedi ,Benedikt Proffen ,Babak Dashtdar ,Mahdi Aghaalikhani ,Daniel Richard ,Vicki Rosen ,Ata M Kiapour ,Terence D Capellini

High-Grade Round Cell Neoplasm Presenting as an Anterior Mediastinal Mass With Features of Desmoplastic Round Cell Tumour

表现为前纵隔肿块的高级别圆形细胞肿瘤,具有促纤维增生性圆形细胞肿瘤的特征

Thomas, Maridas T

Targeting the Alk4 pathway protects against age-related bone loss

靶向ALK4通路可预防与年龄相关的骨质流失。

Maridas, David E; Chim, Shek M; Burton, Kathryn M; Doren, Emily Van; Gamer, Laura; Kirshen, Kyle; Keles, Eren; Avalos, Karla; Kethani, Radhika S; Rosen, Vicki

PPARγ agonist treatment reduces fibroadipose tissue in secondary lymphedema by exhausting fibroadipogenic PDGFRα+ mesenchymal cells

PPARγ 激动剂治疗通过消耗纤维脂肪生成的 PDGFRα+ 间充质细胞来减少继发性淋巴水肿中的纤维脂肪组织

Ziyu Chen, Soheila Ali Akbari Ghavimi, Mengfan Wu, John McNamara, Olga Barreiro, David Maridas, Radomir Kratchmarov, Ashley Siegel, Sarah Djeddi, Maria Gutierrez-Arcelus, Patrick J Brennan, Timothy P Padera, Ulrich von Andrian, Babak Mehrara, Arin K Greene, C Ronald Kahn, Dennis P Orgill, Indranil S

A periosteum-derived cell line to study the role of BMP/TGFβ signaling in periosteal cell behavior and function

骨膜衍生细胞系,用于研究 BMP/TGFβ 信号在骨膜细胞行为和功能中的作用

Emily R Moore, David E Maridas, Laura Gamer, Gavin Chen, Kathryn Burton, Vicki Rosen

Sfrp4 is required to maintain Ctsk-lineage periosteal stem cell niche function

Sfrp4 是维持 Ctsk 谱系骨膜干细胞生态位功能所必需的

Ruiying Chen, Han Dong, Dhairya Raval, David Maridas, Sudipta Baroi, Kun Chen, Dorothy Hu, Shawn R Berry, Roland Baron, Matthew B Greenblatt, Francesca Gori

Loss of Vlk in Prx1+ Cells Delays the Initial Steps of Endochondral Bone Formation and Fracture Repair in the Limb

Prx1+ 细胞中 Vlk 的缺失会延迟肢体内软骨骨形成和骨折修复的初始步骤

David E Maridas, Laura Gamer, Emily R Moore, Annemiek M Doedens, Yunqing Yu, Andreia Ionescu, Leila Revollo, Malcolm Whitman, Vicki Rosen