日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

The MEK inhibitor selumetinib complements CTLA-4 blockade by reprogramming the tumor immune microenvironment

MEK 抑制剂 Selumetinib 通过重新编程肿瘤免疫微环境来补充 CTLA-4 阻断

Edmund Poon, Stefanie Mullins, Amanda Watkins, Geoffrey S Williams, Jens-Oliver Koopmann, Gianfranco Di Genova, Marie Cumberbatch, Margaret Veldman-Jones, Shaun E Grosskurth, Vasu Sah, Alwin Schuller, Corrine Reimer, Simon J Dovedi, Paul D Smith, Ross Stewart, Robert W Wilkinson

Identification of a subset of human non-small cell lung cancer patients with high PI3Kβ and low PTEN expression, more prevalent in squamous cell carcinoma

鉴定出一组具有高 PI3Kβ 和低 PTEN 表达的人类非小细胞肺癌患者,在鳞状细胞癌中更为普遍

Marie Cumberbatch, Ximing Tang, Garry Beran, Sonia Eckersley, Xin Wang, Rebecca P A Ellston, Simon Dearden, Sabina Cosulich, Paul D Smith, Carmen Behrens, Edward S Kim, Xinying Su, Shuqiong Fan, Neil Gray, David P Blowers, Ignacio I Wistuba, Chris Womack

AZD3514: a small molecule that modulates androgen receptor signaling and function in vitro and in vivo

AZD3514:一种小分子,可在体外和体内调节雄激素受体信号传导和功能。

Sarah A Loddick,Sarah J Ross, Andrew G Thomason, David M Robinson, Graeme E Walker, Tom P J Dunkley, Sandra R Brave, Nicola Broadbent, Natalie C Stratton, Dawn Trueman, Elizabeth Mouchet, Fadhel S Shaheen, Vivien N Jacobs, Marie Cumberbatch, Joanne Wilson, Rhys D O Jones, Robert H Bradbury, Alfred Rabow, Luke Gaughan, Chris Womack, Simon T Barry, Craig N Robson, Susan E Critchlow, Stephen R Wedge, A Nigel Brooks

IL-18 is a key proximal mediator of contact hypersensitivity and allergen-induced Langerhans cell migration in murine epidermis

IL-18 是小鼠表皮接触性超敏反应和过敏原诱导的朗格汉斯细胞迁移的关键近端介质

Christos Antonopoulos, Marie Cumberbatch, John B Mee, Rebecca J Dearman, Xiao-Qing Wei, Foo Y Liew, Ian Kimber, Richard W Groves