Stearoyl-CoA desaturase inhibition normalizes brain lipid saturation, α-synuclein homeostasis, and motor function in mutant Gba1-Parkinson mice
硬脂酰辅酶A去饱和酶抑制剂可使突变型Gba1帕金森小鼠的脑脂质饱和度、α-突触核蛋白稳态和运动功能恢复正常。
期刊:JCI Insight
影响因子:6.3
doi:10.1172/jci.insight.188413
Silke Nuber ,Harrison Hsiang ,Esra'a Keewan ,Tim E Moors ,Sydney J Reitz ,Anupama Tiwari ,Gary Ph Ho ,Elena Su ,Wolf Hahn ,Marie-Alexandre Adom ,Riddhima Pathak ,Matthew Blizzard ,Sangjune Kim ,Han Seok Ko ,Xiaoqun Zhang ,Per Svenningsson ,Dennis J Selkoe ,Saranna Fanning
