日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

A stapled lipopeptide platform for preventing and treating highly pathogenic viruses of pandemic potential

用于预防和治疗可能引起大流行的高致病性病毒的钉合脂肽平台

Gregory H Bird, J J Patten, William Zavadoski, Nicole Barucci, Marina Godes, Benjamin M Moyer, Callum D Owen, Paul DaSilva-Jardine, Donna S Neuberg, Richard A Bowen, Robert A Davey, Loren D Walensky

Dissecting the neuroprotective interaction between the BH4 domain of BCL-w and the IP3 receptor

解析BCL-w的BH4结构域与IP3受体之间的神经保护性相互作用

Sophia X Tang ,Christina M Camara ,Joy A Franco ,Maria F Pazyra-Murphy ,Yihang Li ,Marina Godes ,Benjamin M Moyer ,Gregory H Bird ,Rosalind A Segal ,Loren D Walensky

Targeting MCL-1 triggers DNA damage and an anti-proliferative response independent from apoptosis induction

靶向MCL-1可引发DNA损伤和抗增殖反应,且该反应独立于细胞凋亡诱导。

Utsarga Adhikary ,Joao A Paulo ,Marina Godes ,Shrabasti Roychoudhury ,Michelle S Prew ,Yael Ben-Nun ,Ellen W Yu ,Amit Budhraja ,Joseph T Opferman ,Dipanjan Chowdhury ,Steven P Gygi ,Loren D Walensky

Direct inhibition of oncogenic KRAS by hydrocarbon-stapled SOS1 helices

碳氢化合物固定的 SOS1 螺旋直接抑制致癌基因 KRAS

Elizaveta S Leshchiner, Andrey Parkhitko, Gregory H Bird, James Luccarelli, Joseph A Bellairs, Silvia Escudero, Kwadwo Opoku-Nsiah, Marina Godes, Norbert Perrimon, Loren D Walensky

A stapled BIM peptide overcomes apoptotic resistance in hematologic cancers

钉合 BIM 肽可克服血液癌症中的凋亡抗性

James L LaBelle, Samuel G Katz, Gregory H Bird, Evripidis Gavathiotis, Michelle L Stewart, Chelsea Lawrence, Jill K Fisher, Marina Godes, Kenneth Pitter, Andrew L Kung, Loren D Walensky