日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Early elevated IFNα is a key mediator of HIV pathogenesis

早期升高的 IFNα 是 HIV 发病机制的关键介质

Hélène Le Buanec, Valérie Schiavon, Marine Merandet, Alexandre How-Kit, David Bergerat, Céline Fombellida-Lopez, Armand Bensussan, Jean-David Bouaziz, Arsène Burny, Gilles Darcis, Hongshuo Song, Mohammad M Sajadi, Shyamasundaran Kottilil, Robert C Gallo, Daniel Zagury1

IFNα induces CCR5 in CD4+ T-cells, causing its anti- HIV inefficiency and its subsequent pathogenic elevation, partially controlled by anti-HIV therapy

IFNα 诱导 CD4+ T 细胞中的 CCR5,导致其抗 HIV 效率低下以及随后的致病性升高,部分受抗 HIV 疗法控制

Hélène Le Buanec, Valérie Schiavon, Marine Merandet, Alexandre How-Kit, Hongshuo Song, David Bergerat, Céline Fombellida-Lopez, Armand Bensussan, Jean-David Bouaziz, Arsène Burny, Gilles Darcis, Mohammad M Sajadi, Shyamasundaran Kottilil, Daniel Zagury, Robert C Gallo