Mario Merlini相关文献与解析，生知库 | 链接生命科学的每一步

Left ventriculo-arterial coupling in a contemporary cohort of patients with wild-type transthyretin cardiac amyloidosis treated with tafamidis

在接受他法米地治疗的当代野生型转甲状腺素蛋白心脏淀粉样变性患者队列中，左心室-动脉耦合情况

Sanna, Giuseppe Damiano; Di Simone, Valeria Anna; Milani, Paolo; Fogliani, Alessandro; Mussinelli, Roberta; Guida, Gianluigi; Attanasio, Andrea; Obici, Laura; Basset, Marco; Nanci, Martina; Foli, Andrea; Casu, Gavino; De Luca, Leonardo; Nuvolone, Mario; Merlini, Giampaolo; Perlini, Stefano; Palladini, Giovanni

免疫/内分泌

发表日期：2026

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Daratumumab-based regimens versus CyBorD in newly diagnosed patients with AL amyloidosis and IIIb cardiac stage: A matched case-control study

达雷妥尤单抗联合方案与环磷酰胺、双膦酸盐和地塞米松联合方案治疗新诊断的AL淀粉样变性伴IIIb期心脏疾病患者的比较：一项匹配病例对照研究

期刊:Hemasphere

影响因子:14.6

doi:10.1002/hem3.70112

Bellofiore, Claudia; Basset, Marco; Sanna, Giuseppe Damiano; Foli, Andrea; Mussinelli, Roberta; Nanci, Martina; Fogliani, Alessandro; Ciardo, Martina; Nuvolone, Mario; Merlini, Giampaolo; Palladini, Giovanni; Milani, Paolo

心脏病

发表日期：2025

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CNS-associated macrophages contribute to intracerebral aneurysm pathophysiology

中枢神经系统相关巨噬细胞促进脑动脉瘤病理生理学

期刊:Acta Neuropathologica Communications

影响因子:6.2

doi:10.1186/s40478-024-01756-5

Martina Glavan, Ana Jelic, Damien Levard, Juhana Frösen, Sara Keränen, Bart A A Franx, Ana-Rita Bras, Estelle R Louet, Ádám Dénes, Mario Merlini, Denis Vivien, Marina Rubio

Microglial Gi-dependent dynamics regulate brain network hyperexcitability

小胶质细胞 Gi 依赖性动力学调节大脑网络过度兴奋

期刊:Nature Neuroscience

影响因子:21.2

doi:10.1038/s41593-020-00756-7

Mario Merlini #, Victoria A Rafalski #, Keran Ma, Keun-Young Kim, Eric A Bushong, Pamela E Rios Coronado, Zhaoqi Yan, Andrew S Mendiola, Elif G Sozmen, Jae Kyu Ryu, Matthias G Haberl, Matthew Madany, Daniel Naranjo Sampson, Mark A Petersen, Sophia Bardehle, Reshmi Tognatta, Terry Dean Jr, Rosa Meza

TNF-α antagonism rescues the effect of ageing on stroke: Perspectives for targeting inflamm-ageing

TNF-α 拮抗剂可挽救衰老对中风的影响：针对炎症衰老的前景

期刊:European Journal of Clinical Investigation

影响因子:4.4

doi:10.1111/eci.13600

Luca Liberale, Nicole R Bonetti, Yustina M Puspitasari, Ana Vukolic, Alexander Akhmedov, Candela Diaz-Cañestro, Stephan Keller, Fabrizio Montecucco, Mario Merlini, Aurora Semerano, Giacomo Giacalone, Marco Bacigaluppi, Maria Sessa, Frank Ruschitzka, Thomas F Lüscher, Peter Libby, Jürg H Beer, Giovan

In vivo two-photon microscopy protocol for imaging microglial responses and spine elimination at sites of fibrinogen deposition in mouse brain

用于成像小鼠脑纤维蛋白原沉积部位的小胶质细胞反应和脊柱消除的体内双光子显微镜协议

期刊:STAR Protocols

影响因子:1.3

doi:10.1016/j.xpro.2021.100638

Reshmi Tognatta, Mario Merlini, Zhaoqi Yan, Renaud Schuck, Dimitrios Davalos, Katerina Akassoglou

Transcriptional profiling and therapeutic targeting of oxidative stress in neuroinflammation

神经炎症中氧化应激的转录分析和治疗靶向

期刊:Nature Immunology

影响因子:27.7

doi:10.1038/s41590-020-0654-0

Andrew S Mendiola #, Jae Kyu Ryu #, Sophia Bardehle, Anke Meyer-Franke, Kenny Kean-Hooi Ang, Chris Wilson, Kim M Baeten, Kristina Hanspers, Mario Merlini, Sean Thomas, Mark A Petersen, Alexander Williams, Reuben Thomas, Victoria A Rafalski, Rosa Meza-Acevedo, Reshmi Tognatta, Zhaoqi Yan, Samuel J Pf

免疫

神经

神经炎症

Immunology/Inflammation

FA10

发表日期：2020

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Fibrinogen Induces Microglia-Mediated Spine Elimination and Cognitive Impairment in an Alzheimer's Disease Model

纤维蛋白原在阿尔茨海默病模型中诱导小胶质细胞介导的脊柱消除和认知障碍

期刊:Neuron

影响因子:14.7

doi:10.1016/j.neuron.2019.01.014

Mario Merlini, Victoria A Rafalski, Pamela E Rios Coronado, T Michael Gill, Maya Ellisman, Gayathri Muthukumar, Keshav S Subramanian, Jae Kyu Ryu, Catriona A Syme, Dimitrios Davalos, William W Seeley, Lennart Mucke, Robert B Nelson, Katerina Akassoglou

Deleterious role of endothelial lectin-like oxidized low-density lipoprotein receptor-1 in ischaemia/reperfusion cerebral injury

内皮凝集素样氧化低密度脂蛋白受体-1在缺血/再灌注脑损伤中的有害作用

期刊:Journal of Cerebral Blood Flow and Metabolism

影响因子:4.9

doi:10.1177/0271678X18793266

Alexander Akhmedov, Nicole R Bonetti, Martin F Reiner, Remo D Spescha, Heidi Amstalden, Mario Merlini, Daniel S Gaul, Candela Diaz-Cañestro, Sylvie Briand-Schumacher, Rebecca S Spescha, Aurora Semerano, Giacomo Giacalone, Gianluigi Savarese, Fabrizio Montecucco, Luka Kulic, Roger M Nitsch, Christian

信号转导

发表日期：2019

文献求助收藏

Reply: Refining Free Light Chain Ratio in Systemic Amyloidosis

回复：优化系统性淀粉样变性中的游离轻链比例

Left ventriculo-arterial coupling in a contemporary cohort of patients with wild-type transthyretin cardiac amyloidosis treated with tafamidis

在接受他法米地治疗的当代野生型转甲状腺素蛋白心脏淀粉样变性患者队列中，左心室-动脉耦合情况

Daratumumab-based regimens versus CyBorD in newly diagnosed patients with AL amyloidosis and IIIb cardiac stage: A matched case-control study

达雷妥尤单抗联合方案与环磷酰胺、双膦酸盐和地塞米松联合方案治疗新诊断的AL淀粉样变性伴IIIb期心脏疾病患者的比较：一项匹配病例对照研究

CNS-associated macrophages contribute to intracerebral aneurysm pathophysiology

中枢神经系统相关巨噬细胞促进脑动脉瘤病理生理学

Microglial Gi-dependent dynamics regulate brain network hyperexcitability

小胶质细胞 Gi 依赖性动力学调节大脑网络过度兴奋

TNF-α antagonism rescues the effect of ageing on stroke: Perspectives for targeting inflamm-ageing

TNF-α 拮抗剂可挽救衰老对中风的影响：针对炎症衰老的前景

In vivo two-photon microscopy protocol for imaging microglial responses and spine elimination at sites of fibrinogen deposition in mouse brain

用于成像小鼠脑纤维蛋白原沉积部位的小胶质细胞反应和脊柱消除的体内双光子显微镜协议

Transcriptional profiling and therapeutic targeting of oxidative stress in neuroinflammation

神经炎症中氧化应激的转录分析和治疗靶向

Fibrinogen Induces Microglia-Mediated Spine Elimination and Cognitive Impairment in an Alzheimer's Disease Model

纤维蛋白原在阿尔茨海默病模型中诱导小胶质细胞介导的脊柱消除和认知障碍

Deleterious role of endothelial lectin-like oxidized low-density lipoprotein receptor-1 in ischaemia/reperfusion cerebral injury

内皮凝集素样氧化低密度脂蛋白受体-1在缺血/再灌注脑损伤中的有害作用