Mark Brian L相关文献与解析，生知库 | 链接生命科学的每一步

Generation of mice with combined Hexa Gly269Ser KI or KO and Neu3 KO alleles to create new models of GM2 gangliosidoses

构建同时携带 Hexa Gly269Ser KI 或 KO 和 Neu3 KO 等位基因的小鼠模型，以建立新的 GM2 神经节苷脂沉积症模型。

doi:10.1242/bio.062045

Barker, Emily N; Ashiri, Mehrafarin; Saville, Jennifer T; Hemming, Richard; Furletti, Nikolas; Dhume, Shreya H; Yu, Shirley; Anjos, Elaine; Wu, Xiaoli; Fresnoza, Agnes; Merz, David C; Jackson, Mike; Del Bigio, Marc R; Siddiqui, Tabrez J; Fuller, Maria; Mark, Brian L; Triggs-Raine, Barbara

发表日期：2025

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Biochemical Insights into Imipenem Collateral Susceptibility Driven by ampC Mutations Conferring Ceftolozane/Tazobactam Resistance in Pseudomonas aeruginosa

铜绿假单胞菌中由ampC突变驱动的亚胺培南协同敏感性的生化研究揭示了其对头孢洛扎/他唑巴坦的耐药性

期刊:Antimicrobial Agents and Chemotherapy

影响因子:4.5

doi:10.1128/aac.01409-22

Cabot, Gabriel; Kim, Kihun; Mark, Brian L; Oliver, Antonio; Khajehpour, Mazdak

发表日期：2023

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Adding Insult to Injury: Mechanistic Basis for How AmpC Mutations Allow Pseudomonas aeruginosa To Accelerate Cephalosporin Hydrolysis and Evade Avibactam

雪上加霜：AmpC 突变如何使铜绿假单胞菌加速头孢菌素水解并逃避阿维巴坦的机制基础

期刊:Antimicrobial Agents and Chemotherapy

影响因子:4.5

doi:10.1128/AAC.00894-20

Slater, Cole L; Winogrodzki, Judith; Fraile-Ribot, Pablo A; Oliver, Antonio; Khajehpour, Mazdak; Mark, Brian L

发表日期：2020

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Independent inhibition of the polymerase and deubiquitinase activities of the Crimean-Congo Hemorrhagic Fever Virus full-length L-protein

独立抑制克里米亚-刚果出血热病毒全长L蛋白的聚合酶和去泛素化酶活性

期刊:PLoS Neglected Tropical Diseases

影响因子:3.4

doi:10.1371/journal.pntd.0008283

Tchesnokov, Egor P; Bailey-Elkin, Ben A; Mark, Brian L; Götte, Matthias

Molecular Basis for the Potent Inhibition of the Emerging Carbapenemase VCC-1 by Avibactam

阿维巴坦强效抑制新兴碳青霉烯酶VCC-1的分子机制

期刊:Antimicrobial Agents and Chemotherapy

影响因子:4.5

doi:10.1128/AAC.02112-18

Mangat, Chand S; Vadlamani, Grishma; Holicek, Viktor; Chu, Mitchell; Larmour, Veronica L C; Vocadlo, David J; Mulvey, Michael R; Mark, Brian L

发表日期：2019

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Conformational flexibility of the glycosidase NagZ allows it to bind structurally diverse inhibitors to suppress β-lactam antibiotic resistance

糖苷酶NagZ的构象灵活性使其能够结合结构多样的抑制剂，从而抑制β-内酰胺类抗生素耐药性。

期刊:Protein Science

影响因子:5.2

doi:10.1002/pro.3166

Vadlamani, Grishma; Stubbs, Keith A; Désiré, Jérôme; Blériot, Yves; Vocadlo, David J; Mark, Brian L

发表日期：2017

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Structure and Function of Viral Deubiquitinating Enzymes

病毒去泛素化酶的结构和功能

期刊:Journal of Molecular Biology

影响因子:4.5

doi:10.1016/j.jmb.2017.06.010

Bailey-Elkin, Ben A; Knaap, Robert C M; Kikkert, Marjolein; Mark, Brian L

The β-lactamase gene regulator AmpR is a tetramer that recognizes and binds the D-Ala-D-Ala motif of its repressor UDP-N-acetylmuramic acid (MurNAc)-pentapeptide

β-内酰胺酶基因调节因子AmpR是一种四聚体，它能识别并结合其阻遏物UDP-N-乙酰胞壁酸（MurNAc）五肽的D-Ala-D-Ala基序。

期刊:Journal of Biological Chemistry

影响因子:3.9

doi:10.1074/jbc.M114.618199

Vadlamani, Grishma; Thomas, Misty D; Patel, Trushar R; Donald, Lynda J; Reeve, Thomas M; Stetefeld, Jörg; Standing, Kenneth G; Vocadlo, David J; Mark, Brian L

发表日期：2015

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Transactivation of programmed ribosomal frameshifting by a viral protein

病毒蛋白对程序性核糖体移码的转录激活

期刊:Proceedings of the National Academy of Sciences of the United States of America

影响因子:9.1

doi:10.1073/pnas.1321930111

Li, Yanhua; Treffers, Emmely E; Napthine, Sawsan; Tas, Ali; Zhu, Longchao; Sun, Zhi; Bell, Susanne; Mark, Brian L; van Veelen, Peter A; van Hemert, Martijn J; Firth, Andrew E; Brierley, Ian; Snijder, Eric J; Fang, Ying

微生物学

发表日期：2014

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Inhibiting Infectious Bronchitis Virus PLpro Using Ubiquitin Variants.

利用泛素变体抑制传染性支气管炎病毒PLpro

Generation of mice with combined Hexa Gly269Ser KI or KO and Neu3 KO alleles to create new models of GM2 gangliosidoses

构建同时携带 Hexa Gly269Ser KI 或 KO 和 Neu3 KO 等位基因的小鼠模型，以建立新的 GM2 神经节苷脂沉积症模型。

Biochemical Insights into Imipenem Collateral Susceptibility Driven by ampC Mutations Conferring Ceftolozane/Tazobactam Resistance in Pseudomonas aeruginosa

铜绿假单胞菌中由ampC突变驱动的亚胺培南协同敏感性的生化研究揭示了其对头孢洛扎/他唑巴坦的耐药性

Adding Insult to Injury: Mechanistic Basis for How AmpC Mutations Allow Pseudomonas aeruginosa To Accelerate Cephalosporin Hydrolysis and Evade Avibactam

雪上加霜：AmpC 突变如何使铜绿假单胞菌加速头孢菌素水解并逃避阿维巴坦的机制基础

Independent inhibition of the polymerase and deubiquitinase activities of the Crimean-Congo Hemorrhagic Fever Virus full-length L-protein

独立抑制克里米亚-刚果出血热病毒全长L蛋白的聚合酶和去泛素化酶活性

Molecular Basis for the Potent Inhibition of the Emerging Carbapenemase VCC-1 by Avibactam

阿维巴坦强效抑制新兴碳青霉烯酶VCC-1的分子机制

Conformational flexibility of the glycosidase NagZ allows it to bind structurally diverse inhibitors to suppress β-lactam antibiotic resistance

糖苷酶NagZ的构象灵活性使其能够结合结构多样的抑制剂，从而抑制β-内酰胺类抗生素耐药性。

Structure and Function of Viral Deubiquitinating Enzymes

病毒去泛素化酶的结构和功能

The β-lactamase gene regulator AmpR is a tetramer that recognizes and binds the D-Ala-D-Ala motif of its repressor UDP-N-acetylmuramic acid (MurNAc)-pentapeptide

β-内酰胺酶基因调节因子AmpR是一种四聚体，它能识别并结合其阻遏物UDP-N-乙酰胞壁酸（MurNAc）五肽的D-Ala-D-Ala基序。

Transactivation of programmed ribosomal frameshifting by a viral protein

病毒蛋白对程序性核糖体移码的转录激活