日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Poly(ADP-ribose) polymerase 9 mediates early protection against Mycobacterium tuberculosis infection by regulating type I IFN production

聚(ADP-核糖)聚合酶9通过调节I型干扰素的产生来介导对结核分枝杆菌感染的早期保护

Shyamala Thirunavukkarasu, Mushtaq Ahmed, Bruce A Rosa, Mark Boothby, Sung Hoon Cho, Javier Rangel-Moreno, Stanley K Mbandi, Valérie Schreiber, Ananya Gupta, Joaquin Zuniga, Makedonka Mitreva, Deepak Kaushal, Thomas J Scriba, Shabaana A Khader

Selective inhibition of mTORC1 in tumor vessels increases antitumor immunity

选择性抑制肿瘤血管中的 mTORC1 可增强抗肿瘤免疫力

Shan Wang, Ariel Raybuck, Eileen Shiuan, Sung Hoon Cho, Qingfei Wang, Dana M Brantley-Sieders, Deanna Edwards, Margaret M Allaman, James Nathan, Keith T Wilson, David DeNardo, Siyuan Zhang, Rebecca Cook, Mark Boothby, Jin Chen

PARP14 Controls the Nuclear Accumulation of a Subset of Type I IFN-Inducible Proteins

PARP14 控制 I 型 IFN 诱导蛋白子集的核积累

Greta Caprara, Elena Prosperini, Viviana Piccolo, Gianluca Sigismondo, Alessia Melacarne, Alessandro Cuomo, Mark Boothby, Maria Rescigno, Tiziana Bonaldi, Gioacchino Natoli

PARP9 and PARP14 cross-regulate macrophage activation via STAT1 ADP-ribosylation

PARP9 和 PARP14 通过 STAT1 ADP 核糖基化交叉调节巨噬细胞活化

Hiroshi Iwata, Claudia Goettsch, Amitabh Sharma, Piero Ricchiuto, Wilson Wen Bin Goh, Arda Halu, Iwao Yamada, Hideo Yoshida, Takuya Hara, Mei Wei, Noriyuki Inoue, Daiju Fukuda, Alexander Mojcher, Peter C Mattson, Albert-László Barabási, Mark Boothby, Elena Aikawa, Sasha A Singh, Masanori Aikawa

Regulation of endothelial cell proliferation and vascular assembly through distinct mTORC2 signaling pathways

通过不同的 mTORC2 信号通路调节内皮细胞增殖和血管组装

Shan Wang, Katherine R Amato, Wenqiang Song, Victoria Youngblood, Keunwook Lee, Mark Boothby, Dana M Brantley-Sieders, Jin Chen

PARP-14 combines with tristetraprolin in the selective posttranscriptional control of macrophage tissue factor expression

PARP-14 与三四脯氨酸结合选择性转录后控制巨噬细胞组织因子表达

M Bilal Iqbal, Michael Johns, Jun Cao, Yu Liu, Sheng-Chun Yu, Gareth D Hyde, Michael A Laffan, Francesco P Marchese, Sung Hoon Cho, Andrew R Clark, Felicity N Gavins, Kevin J Woollard, Perry J Blackshear, Nigel Mackman, Jonathan L Dean, Mark Boothby, Dorian O Haskard

microRNA-mediated regulation of mTOR complex components facilitates discrimination between activation and anergy in CD4 T cells

microRNA 介导的 mTOR 复合物成分调控有助于区分 CD4 T 细胞中的活化和无能

Antoine Marcais, Rory Blevins, Johannes Graumann, Amelie Feytout, Gopuraja Dharmalingam, Thomas Carroll, Inês F Amado, Ludovica Bruno, Keunwook Lee, Thierry Walzer, Matthias Mann, Antonio A Freitas, Mark Boothby, Amanda G Fisher, Matthias Merkenschlager

Murine dendritic cell rapamycin-resistant and rictor-independent mTOR controls IL-10, B7-H1, and regulatory T-cell induction

小鼠树突状细胞雷帕霉素耐药且不依赖 rictor 的 mTOR 控制 IL-10、B7-H1 和调节性 T 细胞诱导

Brian R Rosborough, Dàlia Raïch-Regué, Benjamin M Matta, Keunwook Lee, Boyi Gan, Ronald A DePinho, Holger Hackstein, Mark Boothby, Hēth R Turnquist, Angus W Thomson

STAT4 and T-bet are required for the plasticity of IFN-γ expression across Th2 ontogeny and influence changes in Ifng promoter DNA methylation

STAT4 和 T-bet 是 Th2 个体发育过程中 IFN-γ 表达可塑性所必需的,并影响 Ifng 启动子 DNA 甲基化的变化

Christopher L Williams, Marcia M Schilling, Sung Hoon Cho, Keunwook Lee, Mei Wei, Aditi, Mark Boothby

B cell-intrinsic and -extrinsic regulation of antibody responses by PARP14, an intracellular (ADP-ribosyl)transferase

细胞内在和外在的抗体反应调节由 PARP14(一种细胞内(ADP-核糖基)转移酶)进行

Sung Hoon Cho, Ariel Raybuck, Mei Wei, John Erickson, Ki Taek Nam, Reagan G Cox, Alyssa Trochtenberg, James W Thomas, John Williams, Mark Boothby