日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Multivalent Fluorinated Nanorings for On-Cell 19F NMR

用于细胞 19F NMR 的多价氟化纳米环

Jiaqian Li, Yiao Wang, Mark D Distefano, Carston R Wagner, William C K Pomerantz

Mononuclear phagocyte morphological response to chemoattractants is dependent on geranylgeranyl pyrophosphate

单核吞噬细胞对趋化因子的形态学反应依赖于香叶基香叶基焦磷酸酯。

Steven A Krauklis ,Jamal Hussain ,Katherine M Murphy ,Evan L Dray ,Carey G Ousley ,Katarzyna Justyna ,Mark D Distefano ,Andrew J Steelman ,Daniel B McKim

Targeted Drug Delivery by MMAE Farnesyl-Bioconjugated Multivalent Chemically Self-Assembled Nanorings Induces Potent Receptor-Dependent Immunogenic Cell Death

通过MMAE法尼基生物偶联多价化学自组装纳米环进行靶向药物递送可诱导强效的受体依赖性免疫原性细胞死亡

Yiao Wang ,Ozgun Kilic ,Lakmal Rozumalski ,Mark D Distefano ,Carston R Wagner

Improved synthesis and application of an alkyne-functionalized isoprenoid analogue to study the prenylomes of motor neurons, astrocytes and their stem cell progenitors

炔烃官能化异戊二烯类似物的改进合成和应用,用于研究运动神经元、星形胶质细胞及其干细胞祖细胞的异戊二烯基体

Kiall F Suazo, Vartika Mishra, Sanjay Maity, Shelby A Auger, Katarzyna Justyna, Alex Petre, Linda Ottoboni, Jessica Ongaro, Stefania P Corti, Francesco Lotti, Serge Przedborski, Mark D Distefano

Prenylcysteine oxidase 1 like protein is required for neutrophil bactericidal activities

异戊二烯半胱氨酸氧化酶1样蛋白是中性粒细胞杀菌活性所必需的

Anastasiia Petenkova ,Shelby A Auger ,Jeffrey Lamb ,Daisy Quellier ,Cody Carter ,On Tak To ,Jelena Milosevic ,Rana Barghout ,Abirami Kugadas ,Xiaoxiao Lu ,Jennifer Geddes-McAlister ,Raina Fichorova ,David B Sykes ,Mark D Distefano ,Mihaela Gadjeva

Thinking outside the CaaX-box: an unusual reversible prenylation on ALDH9A1

跳出 CaaX-box 的思维模式:ALDH9A1 上不寻常的可逆异戊烯化

Kiall F Suazo, Jakub Bělíček, Garrett L Schey, Shelby A Auger, Alexandru M Petre, Ling Li, Katarzyna M Błażewska, David Kopečný, Mark D Distefano

GTPase splice variants RAC1 and RAC1B display isoform-specific differences in localization, prenylation, and interaction with the chaperone protein SmgGDS

GTPase 剪接变体 RAC1 和 RAC1B 在定位、异戊烯化和与伴侣蛋白 SmgGDS 的相互作用方面表现出异构体特异性差异

Olivia J Koehn, Ellen Lorimer, Bethany Unger, Ra'Mal Harris, Akansha S Das, Kiall F Suazo, Shelby A Auger, Mark D Distefano, Jeremy W Prokop, Carol L Williams

Directed cell migration towards softer environments

定向细胞迁移至更柔软的环境

Aleksi Isomursu #, Keun-Young Park #, Jay Hou #, Bo Cheng #, Mathilde Mathieu, Ghaidan A Shamsan, Benjamin Fuller, Jesse Kasim, M Mohsen Mahmoodi, Tian Jian Lu, Guy M Genin, Feng Xu, Min Lin, Mark D Distefano, Johanna Ivaska, David J Odde

Structure-Guided Discovery of Potent Antifungals that Prevent Ras Signaling by Inhibiting Protein Farnesyltransferase

通过结构导向发现强效抗真菌药物,这些药物通过抑制蛋白质法尼基转移酶来阻止Ras信号传导。

You Wang,Feng Xu,Connie B Nichols,Yuqian Shi,Homme W Hellinga,J Andrew Alspaugh,Mark D Distefano,Lorena S Beese

Engineering Biomimetic Trogocytosis with Farnesylated Chemically Self-Assembled Nanorings

利用法尼基化化学自组装纳米环构建仿生吞噬作用

Yiao Wang ,Lakmal Rozumalski ,Ozgun Kilic ,Caitlin Lichtenfels ,Jacob Petersberg ,Mark D Distefano ,Carston R Wagner