Structural studies unravel the active conformation of apo RORγt nuclear receptor and a common inverse agonism of two diverse classes of RORγt inhibitors.
结构研究揭示了 apo RORγt 核受体的活性构象以及两类不同的 RORγt 抑制剂的共同反向激动作用
期刊:Journal of Biological Chemistry
影响因子:3.9
doi:10.1074/jbc.M117.789024
Li Xiang, Anderson Marie, Collin Delphine, Muegge Ingo, Wan John, Brennan Debra, Kugler Stanley, Terenzio Donna, Kennedy Charles, Lin Siqi, Labadia Mark E, Cook Brian, Hughes Robert, Farrow Neil A