日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Microglial Homeostasis Requires Balanced CSF-1/CSF-2 Receptor Signaling

小胶质细胞稳态需要平衡的CSF-1/CSF-2受体信号传导

Violeta Chitu ,Fabrizio Biundo ,Gabriel G L Shlager ,Eun S Park ,Ping Wang ,Maria E Gulinello ,Şölen Gokhan ,Harmony C Ketchum ,Kusumika Saha ,Michael A DeTure ,Dennis W Dickson ,Zbignew K Wszolek ,Deyou Zheng ,Andrew L Croxford ,Burkhard Becher ,Daqian Sun ,Mark F Mehler ,E Richard Stanley

Loss-of-Huntingtin in Medial and Lateral Ganglionic Lineages Differentially Disrupts Regional Interneuron and Projection Neuron Subtypes and Promotes Huntington's Disease-Associated Behavioral, Cellular, and Pathological Hallmarks

内侧和外侧神经节谱系中亨廷顿蛋白的缺失会差异性地破坏区域中间神经元和投射神经元亚型,并促进亨廷顿氏病相关的行为、细胞和病理特征

Mark F Mehler, Jenna R Petronglo, Eduardo E Arteaga-Bracho, Maria E Gulinello, Michael L Winchester, Nandini Pichamoorthy, Stephen K Young, Christopher D DeJesus, Hifza Ishtiaq, Solen Gokhan, Aldrin E Molero

Increased localization of APP-C99 in mitochondria-associated ER membranes causes mitochondrial dysfunction in Alzheimer disease

APP-C99 在线粒体相关内质网膜上的定位增加导致阿尔茨海默病中的线粒体功能障碍

Marta Pera, Delfina Larrea, Cristina Guardia-Laguarta, Jorge Montesinos, Kevin R Velasco, Rishi R Agrawal, Yimeng Xu, Robin B Chan, Gilbert Di Paolo, Mark F Mehler, Geoffrey S Perumal, Frank P Macaluso, Zachary Z Freyberg, Rebeca Acin-Perez, Jose Antonio Enriquez, Eric A Schon, Estela Area-Gomez

Receptor-type protein-tyrosine phosphatase ζ is a functional receptor for interleukin-34

受体型蛋白酪氨酸磷酸酶ζ是白细胞介素-34的功能性受体

Sayan Nandi, Mario Cioce, Yee-Guide Yeung, Edward Nieves, Lydia Tesfa, Haishan Lin, Amy W Hsu, Robert Halenbeck, Hui-Yong Cheng, Solen Gokhan, Mark F Mehler, E Richard Stanley

Selective roles of normal and mutant huntingtin in neural induction and early neurogenesis

正常和突变亨廷顿蛋白在神经诱导和早期神经发生中的选择性作用

Giang D Nguyen, Solen Gokhan, Aldrin E Molero, Mark F Mehler

Obesity-associated improvements in metabolic profile through expansion of adipose tissue

通过脂肪组织扩张实现肥胖相关的代谢状况改善

Ja-Young Kim, Esther van de Wall, Mathieu Laplante, Anthony Azzara, Maria E Trujillo, Susanna M Hofmann, Todd Schraw, Jorge L Durand, Hua Li, Guangyu Li, Linda A Jelicks, Mark F Mehler, David Y Hui, Yves Deshaies, Gerald I Shulman, Gary J Schwartz, Philipp E Scherer