日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

A luminescence-based reporter to study tau secretion reveals overlapping mechanisms for the release of healthy and pathological tau

基于发光的研究 tau 分泌的报告基因揭示了健康和病理 tau 释放的重叠机制

Dianne Marquez Lopez, Connor J Maltby, Hannah Warming, Nullin Divecha, Mariana Vargas-Caballero, Mark J Coldwell, Katrin Deinhardt

A 5' UTR GGN repeat controls localisation and translation of a potassium leak channel mRNA through G-quadruplex formation

5’UTR GGN 重复通过 G-四链体的形成控制钾泄漏通道 mRNA 的定位和翻译

Connor J Maltby, James P R Schofield, Steven D Houghton, Ita O'Kelly, Mariana Vargas-Caballero, Katrin Deinhardt, Mark J Coldwell

Regulation of the Elongation Phase of Protein Synthesis Enhances Translation Accuracy and Modulates Lifespan

调节蛋白质合成的延长阶段可提高翻译准确性并调节寿命

Jianling Xie, Viviane de Souza Alves, Tobias von der Haar, Louise O'Keefe, Roman V Lenchine, Kirk B Jensen, Rui Liu, Mark J Coldwell, Xuemin Wang, Christopher G Proud

Stoichiometry of the eIF2B complex is maintained by mutual stabilization of subunits

eIF2B 复合物的化学计量由亚基之间的相互稳定来维持

Noel C Wortham, Joanna D Stewart, Sean Harris, Mark J Coldwell, Christopher G Proud

PEITC-mediated inhibition of mRNA translation is associated with both inhibition of mTORC1 and increased eIF2α phosphorylation in established cell lines and primary human leukemia cells

PEITC 介导的 mRNA 翻译抑制与已建立的细胞系和原代人类白血病细胞中 mTORC1 的抑制和 eIF2α 磷酸化的增加有关

Alison Yeomans, Elizabeth Lemm, Sarah Wilmore, Breeze E Cavell, Beatriz Valle-Argos, Sergey Krysov, Marina Sanchez Hidalgo, Elodie Leonard, Anne E Willis, Francesco Forconi, Freda K Stevenson, Andrew J Steele, Mark J Coldwell, Graham Packham

Phosphorylation of eIF4GII and 4E-BP1 in response to nocodazole treatment: a reappraisal of translation initiation during mitosis

诺考达唑治疗后 eIF4GII 和 4E-BP1 的磷酸化:有丝分裂过程中翻译起始的重新评估

Mark J Coldwell, Joanne L Cowan, Markete Vlasak, Abbie Mead, Mark Willett, Lisa S Perry, Simon J Morley

Inhibition of mammalian target of rapamycin (mTOR) signalling in C2C12 myoblasts prevents myogenic differentiation without affecting the hyperphosphorylation of 4E-BP1

抑制 C2C12 成肌细胞中的哺乳动物雷帕霉素靶蛋白 (mTOR) 信号传导可防止成肌分化,而不会影响 4E-BP1 的过度磷酸化

Mark Willett, Joanne L Cowan, Markete Vlasak, Mark J Coldwell, Simon J Morley

Canonical initiation factor requirements of the Myc family of internal ribosome entry segments

Myc 家族内部核糖体进入片段的典型起始因子要求

Keith A Spriggs, Laura C Cobbold, Catherine L Jopling, Rebecca E Cooper, Lindsay A Wilson, Mark Stoneley, Mark J Coldwell, Didier Poncet, Ya-Ching Shen, Simon J Morley, Martin Bushell, Anne E Willis