日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Concurrent Targeting of HDAC and PI3K to Overcome Phenotypic Heterogeneity of Castration-resistant and Neuroendocrine Prostate Cancers

同时靶向 HDAC 和 PI3K 以克服去势抵抗性和神经内分泌前列腺癌的表型异质性

Ailin Zhang #, Nathan A Lau #, Alicia Wong, Lisha G Brown, Ilsa M Coleman, Navonil De Sarkar, Dapei Li, Diana C DeLucia, Mark P Labrecque, Holly M Nguyen, Jennifer L Conner, Ruth F Dumpit, Lawrence D True, Daniel W Lin, Eva Corey, Joshi J Alumkal, Peter S Nelson, Colm Morrissey, John K Lee

Regulation of CEACAM5 and Therapeutic Efficacy of an Anti-CEACAM5-SN38 Antibody-drug Conjugate in Neuroendocrine Prostate Cancer

CEACAM5 的调节和抗 CEACAM5-SN38 抗体-药物偶联物在神经内分泌前列腺癌中的治疗效果

Diana C DeLucia, Thomas M Cardillo, Lisa Ang, Mark P Labrecque, Ailin Zhang, James E Hopkins, Navonil De Sarkar, Ilsa Coleman, Rui M Gil da Costa, Eva Corey, Lawrence D True, Michael C Haffner, Michael T Schweizer, Colm Morrissey, Peter S Nelson, John K Lee

Cabozantinib can block growth of neuroendocrine prostate cancer patient-derived xenografts by disrupting tumor vasculature

卡博替尼可通过破坏肿瘤血管来阻止神经内分泌前列腺癌患者来源的异种移植瘤的生长

Mark P Labrecque, Lisha G Brown, Ilsa M Coleman, Holly M Nguyen, Daniel W Lin, Eva Corey, Peter S Nelson, Colm Morrissey

The retinoblastoma protein regulates hypoxia-inducible genetic programs, tumor cell invasiveness and neuroendocrine differentiation in prostate cancer cells

视网膜母细胞瘤蛋白调节前列腺癌细胞的缺氧诱导遗传程序、肿瘤细胞侵袭性和神经内分泌分化

Mark P Labrecque, Mandeep K Takhar, Rebecca Nason, Stephanie Santacruz, Kevin J Tam, Shabnam Massah, Anne Haegert, Robert H Bell, Manuel Altamirano-Dimas, Colin C Collins, Frank J S Lee, Gratien G Prefontaine, Michael E Cox, Timothy V Beischlag

A TRIP230-retinoblastoma protein complex regulates hypoxia-inducible factor-1α-mediated transcription and cancer cell invasion

TRIP230-视网膜母细胞瘤蛋白复合物调节缺氧诱导因子-1α介导的转录和癌细胞侵袭

Mark P Labrecque, Mandeep K Takhar, Julienne M Jagdeo, Kevin J Tam, Christina Chiu, Te-Yu Wang, Gratien G Prefontaine, Michael E Cox, Timothy V Beischlag

Epigenetic characterization of the growth hormone gene identifies SmcHD1 as a regulator of autosomal gene clusters

生长激素基因的表观遗传表征表明 SmcHD1 是常染色体基因簇的调节剂

Shabnam Massah, Robert Hollebakken, Mark P Labrecque, Addie M Kolybaba, Timothy V Beischlag, Gratien G Prefontaine