日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

CMS subtypes correlate with complete response in trial of neoadjuvant Galunisertib plus chemoradiation in rectal cancer

CMS亚型与新辅助Galunisertib联合放化疗治疗直肠癌的试验中完全缓解相关

期刊:Translational Oncology
影响因子:4.1
doi:10.1016/j.tranon.2026.102690
Rajamanickam, Venkatesh; Simons, Noah D; Rosales, Wesley; Kravchenko, Anton; Yamazaki, Tomoko; Bernard, Brady; Piening, Brian; Domingo, Enric; Maughan, Timothy; Alvarez-Jimenez, Charlems; Desilvio, Thomas; Viswanath, Satish; Whiteford, Mark; Hayman, Amanda; O'Brien, David; Kiely, Maria X; Ahmad, Rehan; Gough, Michael J; Crittenden, Marka R; Young, Kristina H
肿瘤
肠癌
肿瘤免疫
多发性硬化症
发表日期：2026
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Fluorescence tracking Treg movement identifies anti-CCR8 and radiation as a therapeutic combination.

荧光追踪 Treg 的运动表明抗 CCR8 和放射疗法是一种有效的联合治疗方案。

期刊:iScience
影响因子:4.1
doi:10.1016/j.isci.2025.114572
Friedman David J, Ramin Sina, Blair Tiffany, Kramer Gwen, Bambina Shelly, Alice Alejandro F, Baird Jason, Medler Terry, Young Kristina H, Crittenden Marka R, Gough Michael J
IF
CCR8
T细胞
Treg
发表日期：2026
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TGFβ limits proximal CD8+ TCR signaling via PTPN22 following strong and moderate agonism

TGFβ 在强激动剂和中等激动剂作用后通过 PTPN22 限制近端 CD8+ TCR 信号传导

期刊:Journal of Immunology
影响因子:3.4
doi:10.1093/jimmun/vkaf216
Gunderson, Andrew J; Jordan, Kelley; Yamazaki, Tomoko; Raué, Hans-Peter; Kramer, Gwen; Fox, Nathaniel; Slifka, Mark K; Gough, Michael J; Crittenden, Marka R; Young, Kristina H
信号转导
T细胞
CD8
TGFβ
发表日期：2025
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Intratumoral radiation dose heterogeneity augments antitumor immunity in mice and primes responses to checkpoint blockade

肿瘤内放射剂量异质性增强小鼠的抗肿瘤免疫力并启动对检查点阻断的反应

期刊:Science Translational Medicine
影响因子:15.8
doi:10.1126/scitranslmed.adk0642
Justin C Jagodinsky,Jessica M Vera,Won Jong Jin,Amanda G Shea,Paul A Clark,Raghava N Sriramaneni,Thomas C Havighurst,Ishan Chakravarthy,Raad H Allawi,KyungMann Kim,Paul M Harari,Paul M Sondel,Michael A Newton,Marka R Crittenden,Michael J Gough,Jessica R Miller,Irene M Ong,Zachary S Morris
肿瘤
免疫/内分泌
Checkpoint
肿瘤免疫
发表日期：2024
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A novel small molecule Enpp1 inhibitor improves tumor control following radiation therapy by targeting stromal Enpp1 expression

一种新型小分子 Enpp1 抑制剂通过靶向基质 Enpp1 表达来改善放射治疗后的肿瘤控制

期刊:Scientific Reports
影响因子:3.8
doi:10.1038/s41598-024-80677-8
Jason R Baird, Alejandro F Alice, Roland Saito, Qingqing Chai, Minhua Han, Cindy Ng, Stephanie Han, Beth Fernandez, Sarah Ledoux, Johannes Grosse, Alan J Korman, Megan Potuznik, Venkatesh Rajamanickam, Brady Bernard, Marka R Crittenden, Michael J Gough
肿瘤
FlowCytometry
发表日期：2024
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Fluorescence tracking demonstrates T cell recirculation is transiently impaired by radiation therapy to the tumor

荧光追踪表明，肿瘤的放射治疗会暂时损害 T 细胞再循环

期刊:Scientific Reports
影响因子:3.8
doi:10.1038/s41598-024-62871-w
Gwen Kramer, Tiffany Blair, Shelly Bambina, Aanchal Preet Kaur, Alejandro Alice, Jason Baird, David Friedman, Alexa K Dowdell, Michio Tomura, Clemens Grassberger, Brian D Piening, Marka R Crittenden, Michael J Gough
肿瘤
T细胞
发表日期：2024
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Myeloid MyD88 restricts CD8(+) T cell response to radiation therapy in pancreatic cancer

髓系MyD88限制胰腺癌中CD8(+) T细胞对放射治疗的反应

期刊:Scientific Reports
影响因子:3.9
doi:10.1038/s41598-023-35834-w
Medler, Terry R; Blair, Tiffany C; Alice, Alejandro F; Dowdell, Alexa K; Piening, Brian D; Crittenden, Marka R; Gough, Michael J
胰腺癌
T细胞
T细胞
CD8
免疫/内分泌
肿瘤
细胞生物学
肿瘤免疫
发表日期：2023
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Tumor resident memory CD8 T cells and concomitant tumor immunity develop independently of CD4 help

肿瘤驻留记忆 CD8 T 细胞和伴随的肿瘤免疫独立于 CD4 帮助而发展

期刊:Scientific Reports
影响因子:3.8
doi:10.1038/s41598-023-33508-1
Terry R Medler, Gwen Kramer, Shelly Bambina, Andrew J Gunderson, Alejandro Alice, Tiffany Blair, Lauren Zebertavage, Thomas Duhen, Rebekka Duhen, Kristina Young, Marka R Crittenden, Michael J Gough
肿瘤
T细胞
发表日期：2023
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ICOS is upregulated on T cells following radiation and agonism combined with radiation results in enhanced tumor control.

放射治疗后，T细胞上的ICOS表达上调，激动剂与放射治疗相结合可增强肿瘤控制

期刊:Scientific Reports
影响因子:3.9
doi:10.1038/s41598-022-19256-8
Blair Tiffany, Baird Jason, Bambina Shelly, Kramer Gwen, Gostissa Monica, Harvey Christopher J, Gough Michael J, Crittenden Marka R
细胞生物学
肿瘤
T细胞
发表日期：2022
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Fluorescent tracking identifies key migratory dendritic cells in the lymph node after radiotherapy

荧光追踪识别放射治疗后淋巴结中的关键迁移树突状细胞

期刊:Life Science Alliance
影响因子:3.3
doi:10.26508/lsa.202101337
Tiffany C Blair, Shelly Bambina, Gwen F Kramer, Alexa K Dowdell, Alejandro F Alice, Jason R Baird, Amanda W Lund, Brian D Piening, Marka R Crittenden, Michael J Gough
细胞生物学
树突状细胞
发表日期：2022
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