日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Human CD4 cytotoxic T lymphocytes mediate potent tumor control in humanized immune system mice

人源CD4细胞毒性T淋巴细胞在人源化免疫系统小鼠中介导有效的肿瘤控制

Wen Lin ,Varan Singh ,Raynel Springer ,Gabrielle Choonoo ,Namita Gupta ,Aditi Patel ,Davor Frleta ,Jun Zhong ,Tomasz Owczarek ,Corinne Decker ,Lynn Macdonald ,Andrew Murphy ,Gavin Thurston ,Markus Mohrs ,Ella Ioffe ,Yi-Fen Lu

Heterogeneity and chimerism of endothelial cells revealed by single-cell transcriptome in orthotopic liver tumors

单细胞转录组学揭示原位肝肿瘤内皮细胞的异质性和嵌合现象

Qi Zhao,Maria Del Pilar Molina-Portela,Asma Parveen,Alexander Adler,Christina Adler,Hock E,Wei Wang,Min Ni,Yi Wei,Gurinder Atwal,Markus Mohrs,Gavin Thurston,Alexandra Eichten

Characterization of the Anti-PD-1 Antibody REGN2810 and Its Antitumor Activity in Human PD-1 Knock-In Mice

抗 PD-1 抗体 REGN2810 的表征及其在人类 PD-1 基因敲入小鼠中的抗肿瘤活性

Elena Burova, Aynur Hermann, Janelle Waite, Terra Potocky, Venus Lai, Seongwon Hong, Matt Liu, Omaira Allbritton, Amy Woodruff, Qi Wu, Amanda D'Orvilliers, Elena Garnova, Ashique Rafique, William Poueymirou, Joel Martin, Tammy Huang, Dimitris Skokos, Joel Kantrowitz, Jon Popke, Markus Mohrs, Douglas

The mechanism of splenic invariant NKT cell activation dictates localization in vivo

脾脏不变 NKT 细胞激活的机制决定了体内定位

Irah L King, Eyal Amiel, Mike Tighe, Katja Mohrs, Natacha Veerapen, Gurdyal Besra, Markus Mohrs, Elizabeth A Leadbetter

Schistosome-derived omega-1 drives Th2 polarization by suppressing protein synthesis following internalization by the mannose receptor

血吸虫衍生的 omega-1 通过抑制甘露糖受体内化后的蛋白质合成来驱动 Th2 极化

Bart Everts, Leonie Hussaarts, Nicole N Driessen, Moniek H J Meevissen, Gabriele Schramm, Alwin J van der Ham, Barbara van der Hoeven, Thomas Scholzen, Sven Burgdorf, Markus Mohrs, Edward J Pearce, Cornelis H Hokke, Helmut Haas, Hermelijn H Smits, Maria Yazdanbakhsh

IL-10R blockade during chronic schistosomiasis mansoni results in the loss of B cells from the liver and the development of severe pulmonary disease

慢性曼氏血吸虫病期间 IL-10R 阻断导致肝脏 B 细胞丢失并引发严重肺部疾病

Keke C Fairfax, Eyal Amiel, Irah L King, Tori C Freitas, Markus Mohrs, Edward J Pearce

Persistent loss of IL-27 responsiveness in CD8+ memory T cells abrogates IL-10 expression in a recall response

CD8+ 记忆 T 细胞中 IL-27 反应性的持续丧失会消除回忆反应中的 IL-10 表达

Georgia Perona-Wright, Jacob E Kohlmeier, Elizabeth Bassity, Tori C Freitas, Katja Mohrs, Tres Cookenham, Haozhong Situ, Edward J Pearce, David L Woodland, Markus Mohrs

Sustained signaling by canonical helper T cell cytokines throughout the reactive lymph node

典型辅助 T 细胞因子在整个反应性淋巴结中持续发出信号

Georgia Perona-Wright, Katja Mohrs, Markus Mohrs

A nonredundant role for IL-21 receptor signaling in plasma cell differentiation and protective type 2 immunity against gastrointestinal helminth infection

IL-21 受体信号在浆细胞分化和针对胃肠道蠕虫感染的保护性 2 型免疫中起非冗余作用

Irah L King, Katja Mohrs, Markus Mohrs

IL-4-producing CD4+ T cells in reactive lymph nodes during helminth infection are T follicular helper cells

蠕虫感染期间反应性淋巴结中产生 IL-4 的 CD4+ T 细胞是 T 滤泡辅助细胞

Irah L King, Markus Mohrs