Markus Rehm相关文献与解析，生知库 | 链接生命科学的每一步

Tobias B Beigl, Alexander Paul, Thomas P Fellmeth, Dang Nguyen, Lynn Barber, Sandra Weller, Benjamin Schäfer, Bernhard F Gillissen, Walter E Aulitzky, Hans-Georg Kopp, Markus Rehm, David W Andrews, Kristyna Pluhackova, Frank Essmann

信号转导

细胞生物学

其它细胞

Proteasome inhibition triggers the formation of TRAIL receptor 2 platforms for caspase-8 activation that accumulate in the cytosol

蛋白酶体抑制会触发 TRAIL 受体 2 平台的形成，从而激活 caspase-8，并在细胞溶胶中积累

期刊:Cell Death and Differentiation

影响因子:13.7

doi:10.1038/s41418-021-00843-7

Christian T Hellwig, M Eugenia Delgado, Josip Skoko #, Lydia Dyck #, Carol Hanna, Alexa Wentges, Claudia Langlais, Cathrin Hagenlocher, Alexandra Mack, David Dinsdale, Kelvin Cain, Marion MacFarlane, Markus Rehm

cFLIP downregulation is an early event required for endoplasmic reticulum stress-induced apoptosis in tumor cells

cFLIP 下调是内质网应激诱导肿瘤细胞凋亡所需的早期事件

期刊:Cell Death & Disease

影响因子:8.1

doi:10.1038/s41419-022-04574-6

Rocío Mora-Molina, Daniela Stöhr, Markus Rehm, Abelardo López-Rivas

ER stress-induced cell death proceeds independently of the TRAIL-R2 signaling axis in pancreatic β cells

内质网应激诱导的胰腺 β 细胞细胞死亡独立于 TRAIL-R2 信号轴进行

期刊:Cell Death Discovery

影响因子:6.1

doi:10.1038/s41420-022-00830-y

Cathrin Hagenlocher, Robin Siebert, Bruno Taschke, Senait Wieske, Angelika Hausser, Markus Rehm

Marizomib sensitizes primary glioma cells to apoptosis induced by a latest-generation TRAIL receptor agonist

Marizomib 使原发性胶质瘤细胞对最新一代 TRAIL 受体激动剂诱导的细胞凋亡敏感

期刊:Cell Death & Disease

影响因子:8.1

doi:10.1038/s41419-021-03927-x

Chiara Boccellato, Emily Kolbe, Nathalie Peters, Viktorija Juric, Gavin Fullstone, Maïté Verreault, Ahmed Idbaih, Martine L M Lamfers, Brona M Murphy, Markus Rehm

Transcriptional CDK inhibitors, CYC065 and THZ1 promote Bim-dependent apoptosis in primary and recurrent GBM through cell cycle arrest and Mcl-1 downregulation

转录 CDK 抑制剂 CYC065 和 THZ1 通过细胞周期停滞和 Mcl-1 下调促进原发性和复发性 GBM 中的 Bim 依赖性细胞凋亡

期刊:Cell Death & Disease

影响因子:8.1

doi:10.1038/s41419-021-04050-7

Viktorija Juric, Lance Hudson, Joanna Fay, Cathy E Richards, Hanne Jahns, Maïté Verreault, Franck Bielle, Ahmed Idbaih, Martine L M Lamfers, Ann M Hopkins, Markus Rehm, Brona M Murphy

Transcriptional CDK Inhibitors CYC065 and THZ1 Induce Apoptosis in Glioma Stem Cells Derived from Recurrent GBM

转录 CDK 抑制剂 CYC065 和 THZ1 诱导复发性胶质母细胞瘤衍生的胶质瘤干细胞凋亡

期刊:Cells

影响因子:5.1

doi:10.3390/cells10051182

Viktorija Juric, Heiko Düssmann, Martine L M Lamfers, Jochen H M Prehn, Markus Rehm, Brona M Murphy

Low-Level Endothelial TRAIL-Receptor Expression Obstructs the CNS-Delivery of Angiopep-2 Functionalised TRAIL-Receptor Agonists for the Treatment of Glioblastoma

低水平内皮 TRAIL 受体表达阻碍血管肽素-2 功能化 TRAIL 受体激动剂向中枢神经系统输送，从而治疗胶质母细胞瘤

期刊:Molecules

影响因子:4.2

doi:10.3390/molecules26247582

Nivetha Krishna Moorthy, Oliver Seifert, Stephan Eisler, Sara Weirich, Roland E Kontermann, Markus Rehm, Gavin Fullstone

Stress-induced TRAILR2 expression overcomes TRAIL resistance in cancer cell spheroids

应激诱导的 TRAILR2 表达可克服癌细胞球体中的 TRAIL 抗性

期刊:Cell Death and Differentiation

影响因子:13.7

doi:10.1038/s41418-020-0559-3

Daniela Stöhr, Jens O Schmid, Tobias B Beigl, Alexandra Mack, Daniela S Maichl, Kai Cao, Beate Budai, Gavin Fullstone, Roland E Kontermann, Thomas E Mürdter, Stephen W G Tait, Cathrin Hagenlocher, Nadine Pollak, Peter Scheurich, Markus Rehm

Why Bax detection in >1400 publications might be flawed

为什么 1400 多篇出版物中的 Bax 检测可能存在缺陷

BCL-2 and BOK regulate apoptosis by interaction of their C-terminal transmembrane domains

BCL-2 和 BOK 通过其 C 端跨膜结构域相互作用调节细胞凋亡

Proteasome inhibition triggers the formation of TRAIL receptor 2 platforms for caspase-8 activation that accumulate in the cytosol

蛋白酶体抑制会触发 TRAIL 受体 2 平台的形成，从而激活 caspase-8，并在细胞溶胶中积累

cFLIP downregulation is an early event required for endoplasmic reticulum stress-induced apoptosis in tumor cells

cFLIP 下调是内质网应激诱导肿瘤细胞凋亡所需的早期事件

ER stress-induced cell death proceeds independently of the TRAIL-R2 signaling axis in pancreatic β cells

内质网应激诱导的胰腺 β 细胞细胞死亡独立于 TRAIL-R2 信号轴进行

Marizomib sensitizes primary glioma cells to apoptosis induced by a latest-generation TRAIL receptor agonist

Marizomib 使原发性胶质瘤细胞对最新一代 TRAIL 受体激动剂诱导的细胞凋亡敏感

Transcriptional CDK inhibitors, CYC065 and THZ1 promote Bim-dependent apoptosis in primary and recurrent GBM through cell cycle arrest and Mcl-1 downregulation

转录 CDK 抑制剂 CYC065 和 THZ1 通过细胞周期停滞和 Mcl-1 下调促进原发性和复发性 GBM 中的 Bim 依赖性细胞凋亡

Transcriptional CDK Inhibitors CYC065 and THZ1 Induce Apoptosis in Glioma Stem Cells Derived from Recurrent GBM

转录 CDK 抑制剂 CYC065 和 THZ1 诱导复发性胶质母细胞瘤衍生的胶质瘤干细胞凋亡

Low-Level Endothelial TRAIL-Receptor Expression Obstructs the CNS-Delivery of Angiopep-2 Functionalised TRAIL-Receptor Agonists for the Treatment of Glioblastoma

低水平内皮 TRAIL 受体表达阻碍血管肽素-2 功能化 TRAIL 受体激动剂向中枢神经系统输送，从而治疗胶质母细胞瘤

Stress-induced TRAILR2 expression overcomes TRAIL resistance in cancer cell spheroids

应激诱导的 TRAILR2 表达可克服癌细胞球体中的 TRAIL 抗性