日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

High-content screening identifies a small molecule that restores AP-4-dependent protein trafficking in neuronal models of AP-4-associated hereditary spastic paraplegia

高内涵筛选鉴定出一种小分子,该小分子可恢复AP-4相关遗传性痉挛性截瘫神经元模型中AP-4依赖性蛋白质运输。

Afshin Saffari ,Barbara Brechmann ,Cedric Böger ,Wardiya Afshar Saber ,Hellen Jumo ,Dosh Whye ,Delaney Wood ,Lara Wahlster ,Julian E Alecu ,Marvin Ziegler ,Marlene Scheffold ,Kellen Winden ,Jed Hubbs ,Elizabeth D Buttermore ,Lee Barrett ,Georg H H Borner ,Alexandra K Davies ,Darius Ebrahimi-Fakhari ,Mustafa Sahin

High-Content Small Molecule Screen Identifies a Novel Compound That Restores AP-4-Dependent Protein Trafficking in Neuronal Models of AP-4-Associated Hereditary Spastic Paraplegia

高内涵小分子筛选鉴定出一种新型化合物,可在 AP-4 相关遗传性痉挛性截瘫的神经元模型中恢复 AP-4 依赖性蛋白质运输

Afshin Saffari, Barbara Brechmann, Cedric Boeger, Wardiya Afshar Saber, Hellen Jumo, Dosh Whye, Delaney Wood, Lara Wahlster, Julian Alecu, Marvin Ziegler, Marlene Scheffold, Kellen Winden, Jed Hubbs, Elizabeth Buttermore, Lee Barrett, Georg Borner, Alexandra Davies, Mustafa Sahin, Darius Ebrahimi-Fa