Calreticulin mutant myeloproliferative neoplasms induce MHC-I skewing, which can be overcome by an optimized peptide cancer vaccine
钙网蛋白突变的骨髓增生性肿瘤会诱发 MHC-I 偏移,可通过优化的肽癌症疫苗来克服
期刊:Science Translational Medicine
影响因子:15.8
doi:10.1126/scitranslmed.aba4380
Mathieu Gigoux, Morten O Holmström, Roberta Zappasodi, Joseph J Park, Stephane Pourpe, Cansu Cimen Bozkus, Levi M B Mangarin, David Redmond, Svena Verma, Sara Schad, Mariam M George, Divya Venkatesh, Arnab Ghosh, David Hoyos, Zaki Molvi, Baransel Kamaz, Anna E Marneth, William Duke, Matthew J Levent