日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Advancing rare disease therapeutics through digital twins: Opportunities in drug development and precision dosing

利用数字孪生技术推进罕见病治疗：药物研发和精准给药的机遇

期刊:Computational and Structural Biotechnology Journal
影响因子:4.1
doi:10.1016/j.csbj.2025.11.047
Dette, Charlotte Maria Ursula; Alberg, Veronika; Rüdesheim, Simeon; Selzer, Dominik; Marok, Fatima Zahra; Bragazzi, Nicola Luigi; Fuhr, Laura Maria; Brunak, Søren; Pearson, Ewan R; Zahn, Tobias; Kiritsi, Dimitra; Schwab, Matthias; Lehr, Thorsten
发表日期：2025
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Physiologically based pharmacokinetic modeling of imatinib and N-desmethyl imatinib for drug-drug interaction predictions

基于生理的伊马替尼和N-去甲基伊马替尼药代动力学模型用于药物相互作用预测

期刊:Cpt-Pharmacometrics & Systems Pharmacology
影响因子:3
doi:10.1002/psp4.13127
Loer, Helena Leonie Hanae; Kovar, Christina; Rüdesheim, Simeon; Marok, Fatima Zahra; Fuhr, Laura Maria; Selzer, Dominik; Schwab, Matthias; Lehr, Thorsten
发表日期：2024
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A physiologically-based pharmacokinetic precision dosing approach to manage dasatinib drug-drug interactions

基于生理药代动力学的精准给药方法用于管理达沙替尼药物相互作用

期刊:Cpt-Pharmacometrics & Systems Pharmacology
影响因子:3
doi:10.1002/psp4.13146
Kovar, Christina; Loer, Helena Leonie Hanae; Rüdesheim, Simeon; Fuhr, Laura Maria; Marok, Fatima Zahra; Selzer, Dominik; Schwab, Matthias; Lehr, Thorsten
发表日期：2024
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A Physiologically Based Pharmacokinetic Model of Ketoconazole and Its Metabolites as Drug-Drug Interaction Perpetrators

基于生理的酮康唑及其代谢物作为药物相互作用因素的药代动力学模型

期刊:Pharmaceutics
影响因子:5.5
doi:10.3390/pharmaceutics15020679
Marok, Fatima Zahra; Wojtyniak, Jan-Georg; Fuhr, Laura Maria; Selzer, Dominik; Schwab, Matthias; Weiss, Johanna; Haefeli, Walter Emil; Lehr, Thorsten
代谢
发表日期：2023
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Physiologically-based pharmacokinetic modeling of quinidine to establish a CYP3A4, P-gp, and CYP2D6 drug-drug-gene interaction network

基于生理的奎尼丁药代动力学模型，构建CYP3A4、P-gp和CYP2D6药物-药物-基因相互作用网络

期刊:Cpt-Pharmacometrics & Systems Pharmacology
影响因子:3
doi:10.1002/psp4.12981
Feick, Denise; Rüdesheim, Simeon; Marok, Fatima Zahra; Selzer, Dominik; Loer, Helena Leonie Hanae; Teutonico, Donato; Frechen, Sebastian; van der Lee, Maaike; Moes, Dirk Jan A R; Swen, Jesse J; Schwab, Matthias; Lehr, Thorsten
CYP3A4
发表日期：2023
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A Physiologically Based Pharmacokinetic and Pharmacodynamic Model of the CYP3A4 Substrate Felodipine for Drug-Drug Interaction Modeling

基于生理的CYP3A4底物非洛地平的药代动力学和药效学模型及其在药物相互作用建模中的应用

期刊:Pharmaceutics
影响因子:5.5
doi:10.3390/pharmaceutics14071474
Fuhr, Laura Maria; Marok, Fatima Zahra; Mees, Maximilian; Mahfoud, Felix; Selzer, Dominik; Lehr, Thorsten
CYP3A4
发表日期：2022
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AIE+ESIPT Active Hydroxybenzothiazole for Intracellular Detection of Cu(2+): Anticancer and Anticounterfeiting Applications

用于细胞内检测 Cu(2+) 的 AIE+ESIPT 活性羟基苯并噻唑：抗癌和防伪应用

期刊:Molecules
影响因子:4.6
doi:10.3390/molecules27227678
Kaur, Rajdeep; Kour, Rasdeep; Marok, Satwinder Singh; Kaur, Satwinderjeet; Singh, Prabhpreet
细胞生物学
肿瘤
肿瘤免疫
发表日期：2022
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Physiologically Based Pharmacokinetic Modeling of Bupropion and Its Metabolites in a CYP2B6 Drug-Drug-Gene Interaction Network

基于生理的安非他酮及其代谢物在CYP2B6药物-药物-基因相互作用网络中的药代动力学模型

期刊:Pharmaceutics
影响因子:5.5
doi:10.3390/pharmaceutics13030331
Marok, Fatima Zahra; Fuhr, Laura Maria; Hanke, Nina; Selzer, Dominik; Lehr, Thorsten
代谢
发表日期：2021
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