日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Asymmetric recognition of the HIV-1 trimer by broadly neutralizing antibody PG9

广谱中和抗体PG9对HIV-1三聚体的不对称识别

Julien, Jean-Philippe; Lee, Jeong Hyun; Cupo, Albert; Murin, Charles D; Derking, Ronald; Hoffenberg, Simon; Caulfield, Michael J; King, C Richter; Marozsan, Andre J; Klasse, Per Johan; Sanders, Rogier W; Moore, John P; Wilson, Ian A; Ward, Andrew B

Broadly neutralizing antibody PGT121 allosterically modulates CD4 binding via recognition of the HIV-1 gp120 V3 base and multiple surrounding glycans

广谱中和抗体 PGT121 通过识别 HIV-1 gp120 V3 碱基及其周围多个聚糖,变构调节 CD4 结合。

Julien, Jean-Philippe; Sok, Devin; Khayat, Reza; Lee, Jeong Hyun; Doores, Katie J; Walker, Laura M; Ramos, Alejandra; Diwanji, Devan C; Pejchal, Robert; Cupo, Albert; Katpally, Umesh; Depetris, Rafael S; Stanfield, Robyn L; McBride, Ryan; Marozsan, Andre J; Paulson, James C; Sanders, Rogier W; Moore, John P; Burton, Dennis R; Poignard, Pascal; Ward, Andrew B; Wilson, Ian A

Partial enzymatic deglycosylation preserves the structure of cleaved recombinant HIV-1 envelope glycoprotein trimers.

部分酶促去糖基化作用保留了裂解的重组 HIV-1 包膜糖蛋白三聚体的结构

Depetris Rafael S, Julien Jean-Philippe, Khayat Reza, Lee Jeong Hyun, Pejchal Robert, Katpally Umesh, Cocco Nicolette, Kachare Milind, Massi Evan, David Kathryn B, Cupo Albert, Marozsan Andre J, Olson William C, Ward Andrew B, Wilson Ian A, Sanders Rogier W, Moore John P

Trimeric HIV-1 glycoprotein gp140 immunogens and native HIV-1 envelope glycoproteins display the same closed and open quaternary molecular architectures

三聚体 HIV-1 糖蛋白 gp140 免疫原和天然 HIV-1 包膜糖蛋白具有相同的封闭和开放的四级分子结构。

Harris, Audray; Borgnia, Mario J; Shi, Dan; Bartesaghi, Alberto; He, Haifeng; Pejchal, Robert; Kang, Yun Kenneth; Depetris, Rafael; Marozsan, Andre J; Sanders, Rogier W; Klasse, Per Johan; Milne, Jacqueline L S; Wilson, Ian A; Olson, William C; Moore, John P; Subramaniam, Sriram

Differences in the fitness of two diverse wild-type human immunodeficiency virus type 1 isolates are related to the efficiency of cell binding and entry

两种不同的野生型人类免疫缺陷病毒1型分离株的适应性差异与细胞结合和入侵效率有关。

Marozsan, Andre J; Moore, Dawn M; Lobritz, Michael A; Fraundorf, Erika; Abraha, Awet; Reeves, Jacqueline D; Arts, Eric J

Monitoring processed, mature Human Immunodeficiency Virus type 1 particles immediately following treatment with a protease inhibitor-containing treatment regimen

在接受含蛋白酶抑制剂的治疗方案后,立即监测已处理的成熟 1 型人类免疫缺陷病毒颗粒。

Baird, Heather A; Marozsan, Andre J; Lederman, Michael M; Landay, Alan; Mildvan, Donna; Kuritzkes, Daniel R; Kessler, Harold A; Arts, Eric J