日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Conformational dynamics of SARS-CoV-2 spike on a membrane reveals the allosteric effects of furin cleavage and the D614G mutation

SARS-CoV-2刺突蛋白在膜上的构象动力学揭示了弗林蛋白酶切割和D614G突变的变构效应。

Shoemaker, Sophie R; Luo, Megan; Dam, Kim-Marie A; Pak, John E; Hoffmann, Magnus A G; Marqusee, Susan

NUB1 traps unfolded FAT10 for ubiquitin-independent degradation by the 26S proteasome.

NUB1 捕获未折叠的 FAT10,使其通过 26S 蛋白酶体进行不依赖泛素的降解

Arkinson Connor, Dong Ken C, Gee Christine L, Costello Shawn M, Soe Aimee Chi, Hura Greg L, Marqusee Susan, Martin Andreas

Cataract-prone variants of γD-crystallin populate a conformation with a partially unfolded N-terminal domain under native conditions.

易患白内障的 γD-晶状体蛋白变体在天然条件下呈现 N 端结构域部分展开的构象

Volz Sara, Malone Jadyn R, Guseman Alex J, Gronenborn Angela M, Marqusee Susan

Exploring the sequence and structural determinants of the energy landscape from thermodynamically stable and kinetically trapped subtilisins: ISP1 and SbtE.

探索热力学稳定和动力学受限的枯草杆菌蛋白酶 ISP1 和 SbtE 的能量景观的序列和结构决定因素

Hood Miriam R, Marqusee Susan

Enabling simultaneous photoluminescence spectroscopy and X-ray footprinting mass spectrometry to study protein conformation and interactions

利用同步光致发光光谱和X射线足迹质谱技术研究蛋白质构象和相互作用

Gupta, Sayan; Russell, Brandon; Kristensen, Line G; Tyler, James; Costello, Shawn M; Marqusee, Susan; Rad, Behzad; Ralston, Corie Y

The Interplay of Furin Cleavage and D614G in Modulating SARS-CoV-2 Spike Protein Dynamics

Furin 切割和 D614G 在调节 SARS-CoV-2 刺突蛋白动力学中的相互作用

Shoemaker, Sophie R; Luo, Megan; Dam, Kim-Marie A; Pak, John E; Hoffmann, Magnus A G; Marqusee, Susan

"Design principles of a membrane-spanning ubiquitin ligase"

“跨膜泛素连接酶的设计原则”

Williams, Carys; Nocka, Laura M; Hedger, George; Parashara, Pragya; Pardon, Els; Latorraca, Naomi R; Pusapati, Ganesh V; Lartey, Dorothy; Gao, Lei; Milenkovic, Ljiljana; Chalk, Rod; Steyaert, Jan; Marqusee, Susan; Carrique, Loïc; Bazan, J Fernando; Rouse, Sarah L; Kong, Jennifer H; Siebold, Christian; Rohatgi, Rajat

Stepwise activation of a metabotropic glutamate receptor.

代谢型谷氨酸受体的逐步激活

Krishna Kumar Kaavya, Wang Haoqing, Habrian Chris, Latorraca Naomi R, Xu Jun, O'Brien Evan S, Zhang Chensong, Montabana Elizabeth, Koehl Antoine, Marqusee Susan, Isacoff Ehud Y, Kobilka Brian K

Selection pressures on evolution of ribonuclease H explored with rigorous free-energy-based design

利用严格的基于自由能的设计方法探索核糖核酸酶H进化过程中的选择压力

Hayes, Ryan L; Nixon, Charlotte F; Marqusee, Susan; Brooks, Charles L 3rd

The importance of input sequence set to consensus-derived proteins and their relationship to reconstructed ancestral proteins

输入序列集对共识衍生蛋白的重要性及其与重建祖先蛋白的关系

Nixon, Charlotte; Lim, Shion A; Sternke, Matt; Barrick, Doug; Harms, Michael J; Marqusee, Susan