Transient inhibition of ROR-γt therapeutically limits intestinal inflammation by reducing TH17 cells and preserving group 3 innate lymphoid cells
短暂抑制ROR-γt可通过减少TH17细胞和保护3型固有淋巴细胞,在治疗上限制肠道炎症。
期刊:Nature Medicine
影响因子:50
doi:10.1038/nm.4046
Withers, David R; Hepworth, Matthew R; Wang, Xinxin; Mackley, Emma C; Halford, Emily E; Dutton, Emma E; Marriott, Clare L; Brucklacher-Waldert, Verena; Veldhoen, Marc; Kelsen, Judith; Baldassano, Robert N; Sonnenberg, Gregory F