日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Epstein-Barr virus reprograms autoreactive B cells as antigen-presenting cells in systemic lupus erythematosus.

在系统性红斑狼疮中,Epstein-Barr 病毒将自身反应性 B 细胞重编程为抗原呈递细胞。

Younis Shady, Moutusy Salvinaz I, Rasouli Sajede, Jahanbani Shaghayegh, Pandit Mahesh, Wu Xiaohao, Acharya Suman, Sharpe Orr, Wijeratne Tilini U, Harris Marlayna L, Yang Emily Y, Chaichian Yashaar, Parsafar Shima, Baker Matthew C, Harley John B, Meffre Eric, Steinman Lawrence, Marshak-Rothstein Ann, James Judith A, Martinez Olivia M, Utz Paul J, Orange Dana E, Lanz Tobias V, Robinson William H

Two distinct durable human class-switched memory B cell populations are induced by vaccination and infection.

疫苗接种和感染可诱导产生两种不同的、持久的人类类别转换记忆B细胞群。

Perugino Cory A, Liu Hang, Feldman Jared, Marbourg Jess, Guy Thomas V, Hui Anson, Ingram Nicole, Liebaert Julian, Chaudhary Neha, Tao Weiyang, Jacob-Dolan Catherine, Hauser Blake M, Mian Zayd, Nathan Anusha, Zhao Zezhou, Kaseke Clarety, Tano-Menka Rhoda, Getz Matthew A, Senjobe Fernando, Berrios Cristhian, Ofoman Onosereme, Manickas-Hill Zachary, Wesemann Duane R, Lemieux Jacob E, Goldberg Marcia B, Nündel Kerstin, Moormann Ann, Marshak-Rothstein Ann, Larocque Regina C, Ryan Edward T, Iafrate John A, Lingwood Daniel, Gaiha Gaurav, Charles Richelle, Balazs Alejandro B, Pandit Aridaman, Naranbhai Vivek, Schmidt Aaaron G, Pillai Shiv

Endothelial Cell Expression of STING (V154M) Gain-of-Function Mutation Delays the Resolution of UVB-induced Skin Injury

内皮细胞中STING(V154M)功能获得性突变的表达会延缓UVB诱导的皮肤损伤的消退

Chuprin, Jane; Lopes, Carolina Salomāo; Gao, Kevin MingJie; Chiang, Kristy; Afshari, Khashayar; Haddadi, Nazgol; Garber, Manuel; Koupenova, Milka; Fitzgerald, Katherine A; Marshak-Rothstein, Ann; Rashighi, Mehdi

IFNγ initiates TLR9-dependent autoimmune hepatitis in DNase II deficient mice

IFNγ在DNase II缺陷小鼠中启动TLR9依赖性自身免疫性肝炎

Hao, Kaiyuan; Gao, Kevin MingJie; Strauss, Melissa; Subramanian, Sharon; Marshak-Rothstein, Ann

Activation of Autoreactive Lymphocytes in the Lung by STING Gain-of-function Mutation Radioresistant Cells

STING功能获得性突变激活肺部自身反应性淋巴细胞 放射抗性细胞

Gao, Kevin MingJie; Nündel, Kerstin; Chiang, Kristy; Yin, Xihui; Utz, Paul J; Fitzgerald, Kate; Marshak-Rothstein, Ann

Disease in the Pld4thss/thss Model of Murine Lupus Requires TLR9

Pld4thss/thss小鼠狼疮模型中的疾病需要TLR9

Gavin, Amanda L; Blane, Tanya R; Thinnes, Therese C; Gerlt, Emma; Marshak-Rothstein, Ann; Huang, Deli; Nemazee, David

IgD(+) age-associated B cells are the progenitors of the main T-independent B cell response to infection that generates protective Ab and can be induced by an inactivated vaccine in the aged

IgD(+) 年龄相关 B 细胞是主要的 T 细胞非依赖性 B 细胞应答的祖细胞,该应答可产生保护性抗体,并且可通过灭活疫苗在老年人群中诱导产生。

Kugler-Umana, Olivia; Zhang, Wenliang; Kuang, Yi; Liang, Jialing; Castonguay, Catherine H; Tonkonogy, Susan L; Marshak-Rothstein, Ann; Devarajan, Priyadharshini; Swain, Susan L

Human nasal wash RNA-Seq reveals distinct cell-specific innate immune responses in influenza versus SARS-CoV-2

人类鼻腔冲洗液RNA测序揭示了流感病毒和SARS-CoV-2病毒中不同的细胞特异性先天免疫反应

Gao, Kevin M; Derr, Alan G; Guo, Zhiru; Nündel, Kerstin; Marshak-Rothstein, Ann; Finberg, Robert W; Wang, Jennifer P

Interplay of Cyclic GMP-AMP Synthase/Stimulator of IFN Genes and Toll-Like Receptor Nucleic Acid Sensing Pathways in Autoinflammation and Abnormal Bone Formation due to DNaseII-Deficiency

环磷酸鸟苷-AMP合成酶/干扰素基因刺激因子与Toll样受体核酸感应通路在DNaseII缺乏引起的自身炎症和异常骨形成中的相互作用

Marshak-Rothstein, Ann; Manning, Catherine A; Baum, Rebecca; Pawaria, Sudesh; Gravallese, Ellen M

The role of nucleic acid sensors and type I IFNs in patient populations and animal models of autoinflammation

核酸传感器和I型干扰素在自身炎症患者群体和动物模型中的作用

Nündel, Kerstin; Marshak-Rothstein, Ann