日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Large-scale Pan-cancer Cell Line Screening Identifies Actionable and Effective Drug Combinations

大规模泛癌细胞系筛选可确定可行且有效的药物组合

Azadeh C Bashi #, Elizabeth A Coker #, Krishna C Bulusu #, Patricia Jaaks #, Claire Crafter #, Howard Lightfoot, Marta Milo, Katrina McCarten, David F Jenkins, Dieudonne van der Meer, James T Lynch, Syd Barthorpe, Courtney L Andersen, Simon T Barry, Alexandra Beck, Justin Cidado, Jacob A Gordon, Cai

The ATR inhibitor ceralasertib potentiates cancer checkpoint immunotherapy by regulating the tumor microenvironment

ATR抑制剂ceralasertib通过调节肿瘤微环境增强癌症检查点免疫疗法的疗效。

Elizabeth L Hardaker # ,Emilio Sanseviero # ,Ankur Karmokar # ,Devon Taylor # ,Marta Milo ,Chrysis Michaloglou ,Adina Hughes ,Mimi Mai ,Matthew King ,Anisha Solanki ,Lukasz Magiera ,Ricardo Miragaia ,Gozde Kar ,Nathan Standifer ,Michael Surace ,Shaan Gill ,Alison Peter ,Sara Talbot ,Sehmus Tohumeken ,Henderson Fryer ,Ali Mostafa ,Kathy Mulgrew ,Carolyn Lam ,Scott Hoffmann ,Daniel Sutton ,Larissa Carnevalli ,Fernando J Calero-Nieto ,Gemma N Jones ,Andrew J Pierce ,Zena Wilson ,David Campbell ,Lynet Nyoni ,Carla P Martins ,Tamara Baker ,Gilberto Serrano de Almeida ,Zainab Ramlaoui ,Abdel Bidar ,Benjamin Phillips ,Joseph Boland ,Sonia Iyer ,J Carl Barrett ,Arsene-Bienvenu Loembé ,Serge Y Fuchs ,Umamaheswar Duvvuri ,Pei-Jen Lou ,Melonie A Nance ,Carlos Alberto Gomez Roca ,Elaine Cadogan ,Susan E Critichlow ,Steven Fawell ,Mark Cobbold ,Emma Dean ,Viia Valge-Archer ,Alan Lau ,Dmitry I Gabrilovich ,Simon T Barry

SRSF1-dependent inhibition of C9ORF72-repeat RNA nuclear export: genome-wide mechanisms for neuroprotection in amyotrophic lateral sclerosis

SRSF1依赖性抑制C9ORF72重复RNA核输出:肌萎缩侧索硬化症神经保护的全基因组机制

Lydia M Castelli # ,Luisa Cutillo # ,Cleide Dos Santos Souza ,Alvaro Sanchez-Martinez ,Ilaria Granata ,Ya-Hui Lin ,Monika A Myszczynska ,Paul R Heath ,Matthew R Livesey ,Ke Ning ,Mimoun Azzouz ,Pamela J Shaw ,Mario R Guarracino ,Alexander J Whitworth ,Laura Ferraiuolo ,Marta Milo ,Guillaume M Hautbergue

Translating SOD1 Gene Silencing toward the Clinic: A Highly Efficacious, Off-Target-free, and Biomarker-Supported Strategy for fALS

将 SOD1 基因沉默转化为临床治疗:一种高效、无脱靶、生物标志物支持的 fALS 策略

Tommaso Iannitti, Joseph M Scarrott, Shibi Likhite, Ian R P Coldicott, Katherine E Lewis, Paul R Heath, Adrian Higginbottom, Monika A Myszczynska, Marta Milo, Guillaume M Hautbergue, Kathrin Meyer, Brian K Kaspar, Laura Ferraiuolo, Pamela J Shaw, Mimoun Azzouz

Production of recombinant 503 antigen of Leishmania infantum chagasi using cultivation in batch and fed-batch

利用分批培养和补料分批培养生产婴儿利什曼原虫重组503抗原

Magariños, Marta; Milo, Marta; Varela-Nieto, Isabel; Ferreira Vaz, Michelle Rossana; Sousa Junior, Francisco Canindé de; Araújo Padilha, Carlos Eduardo de; Arantes Martins, Daniella Regina; Santos, Everaldo Silvino; Macedo, Gorete Ribeiro

Prolyl hydroxylase 3 (PHD3) is essential for hypoxic regulation of neutrophilic inflammation in humans and mice

脯氨酰羟化酶 3 (PHD3) 对人类和小鼠中性粒细胞炎症的缺氧调节至关重要

Sarah R Walmsley, Edwin R Chilvers, Alfred A Thompson, Kathryn Vaughan, Helen M Marriott, Lisa C Parker, Gary Shaw, Selina Parmar, Martin Schneider, Ian Sabroe, David H Dockrell, Marta Milo, Cormac T Taylor, Randall S Johnson, Christopher W Pugh, Peter J Ratcliffe, Patrick H Maxwell, Peter Carmeliet

Regulation of neutrophil senescence by microRNAs

microRNA 对中性粒细胞衰老的调控

Jon R Ward, Paul R Heath, James W Catto, Moira K B Whyte, Marta Milo, Stephen A Renshaw

Genomic analysis of the function of the transcription factor gata3 during development of the mammalian inner ear

转录因子 gata3 在哺乳动物内耳发育过程中的功能基因组分析

Marta Milo, Daniela Cacciabue-Rivolta, Adam Kneebone, Hikke Van Doorninck, Claire Johnson, Grace Lawoko-Kerali, Mahesan Niranjan, Marcelo Rivolta, Matthew Holley