Direct pharmacological AMPK activation inhibits mucosal SARS-CoV-2 infection by reducing lipid metabolism, restoring autophagy flux and the type I IFN response.
直接药理学激活 AMPK 可抑制粘膜 SARS-CoV-2 感染，其机制是通过降低脂质代谢、恢复自噬通量和 I 型 IFN 反应
期刊:Journal of Virology
影响因子:3.8
doi:10.1128/jvi.00394-25
Cottignies-Calamarte Andrea, Marteau Flora, He Feifan, Belouzard Sandrine, Dubuisson Jean, Tudor Daniela, Viollet Benoit, Bomsel Morgane
